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Literature summary for 1.3.1.81 extracted from

  • Ringer, K.L.; Davis, E.M.; Croteau, R.
    Monoterpene metabolism. Cloning, expression, and characterization of (-)-isopiperitenol/(-)-carveol dehydrogenase of peppermint and spearmint (2005), Plant Physiol., 137, 863-872.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2 (+)-pulegone + 2 NADPH + 2 H+ Mentha x piperita pathways of monoterpene biosynthesis, overview (-)-menthone + (+)-isomenthone + 2 NADP+
-
?
2 (+)-pulegone + 2 NADPH + 2 H+ Mentha spicata pathways of monoterpene biosynthesis, overview (-)-menthone + (+)-isomenthone + 2 NADP+
-
?

Organism

Organism UniProt Comment Textmining
Mentha spicata
-
-
-
Mentha x piperita
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2 (+)-pulegone + 2 NADPH + 2 H+
-
Mentha spicata (-)-menthone + (+)-isomenthone + 2 NADP+
-
?
2 (+)-pulegone + 2 NADPH + 2 H+ pathways of monoterpene biosynthesis, overview Mentha x piperita (-)-menthone + (+)-isomenthone + 2 NADP+
-
?
2 (+)-pulegone + 2 NADPH + 2 H+ pathways of monoterpene biosynthesis, overview Mentha spicata (-)-menthone + (+)-isomenthone + 2 NADP+
-
?
2 (+)-pulegone + 2 NADPH + 2 H+ the NADPH-dependent reductase reduces the conjugated double bond to yield both (-)-menthone and (+)-isomenthone Mentha x piperita (-)-menthone + (+)-isomenthone + 2 NADP+
-
?

Synonyms

Synonyms Comment Organism
More the enzyme belongs to the distinct medium chain dehydrogenase/reductase superfamily Mentha x piperita
More the enzyme belongs to the distinct medium chain dehydrogenase/reductase superfamily Mentha spicata

Cofactor

Cofactor Comment Organism Structure
NADPH
-
Mentha x piperita
NADPH
-
Mentha spicata