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Literature summary for 1.3.1.85 extracted from
- CcrR, a TetR family transcriptional regulator, activates the transcription of a gene of the Ethylmalonyl coenzyme A pathway in Methylobacterium extorquens AM1 (2012), J. Bacteriol., 194, 2802-2808.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Methylorubrum extorquens | - |
- |
- |
| Methylorubrum extorquens ATCC 14718 / DSM 1338 / JCM 2805 / NCIMB 9133 / AM1 | - |
- |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| CCR | - |
Methylorubrum extorquens |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Methylorubrum extorquens | TetR-type activator CcrR regulates the expression of crotonyl-CoA reductase/carboxylase. A ccrR null mutant strain ismpaired in its ability to grow on C1 and C2 compounds, correlating with the reduced activity of crotonyl-CoA reductase/carboxylase. The activity of the promoter required for ccr expression decreases as much as 50% in the absence of ccrR compared to wild-type. CcrR directly binds to the region upstream of the katA-ccr promoter | additional information |
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