Literature summary for 1.3.1.9 extracted from

Lee, J.; Park, A.; Chi, Y.; Jeong, A.
Crystal structures of Pseudomonas aeruginosa enoyl-ACP reductase (FabI) in the presence and absence of NAD+ and triclosan (2015), Bull. Korean Chem. Soc., 36, 322-326.

No PubMed abstract available

Search for more literature for 1.3.1.9

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli BL21(DE3) cells	Pseudomonas aeruginosa

Crystallization (Commentary)

Crystallization (Comment)	Organism
apoenzyme and in complex with NAD+ and triclosan, hanging drop vapor diffusion method, using 0.1 M sodium malonate pH 5.0, 10% (w/v) polyethylene glycol 3350	Pseudomonas aeruginosa

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
an acyl-[acyl-carrier protein] + NAD+	Pseudomonas aeruginosa	-	a trans-2,3-dehydroacyl-[acyl-carrier protein] + NADH + H+	-	?

Organism

Organism	UniProt	Comment	Textmining
Pseudomonas aeruginosa	Q9ZFE4	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Pseudomonas aeruginosa

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
an acyl-[acyl-carrier protein] + NAD+	-	Pseudomonas aeruginosa	a trans-2,3-dehydroacyl-[acyl-carrier protein] + NADH + H+	-	?
crotonyl-CoA + NADH + H+	-	Pseudomonas aeruginosa	butyryl-CoA + NAD+	-	?

Subunits

Subunits	Comment	Organism
homotetramer	x-ray crystallography	Pseudomonas aeruginosa

Synonyms

Synonyms	Comment	Organism
enoyl-ACP reductase	-	Pseudomonas aeruginosa
enoyl-acyl carrier protein reductase	-	Pseudomonas aeruginosa
ENR	-	Pseudomonas aeruginosa
FabI	-	Pseudomonas aeruginosa

Cofactor

Cofactor	Comment	Organism	Structure
NAD+	-	Pseudomonas aeruginosa
NADH	-	Pseudomonas aeruginosa

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Release 2023.1 (January 2023)