Literature summary for 1.3.1.9 extracted from

Liu, J.; Wu, J.; Li, Z.
Enoyl acyl carrier protein reductase (FabI) catalyzed asymmetric reduction of the C=C double bond of alpha,beta-unsaturated ketones: preparation of (R)-2-alkyl-cyclopentanones (2014), Chem. Commun. (Camb.), 50, 9729-9732.

Search for more literature for 1.3.1.9

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli BL21(DE3) cells	Acinetobacter sp. RS1

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
28500	-	-	Acinetobacter sp. RS1

Organism

Organism	UniProt	Comment	Textmining
Acinetobacter sp. RS1	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
HisPrep column chromatography	Acinetobacter sp. RS1

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2-butylidene-cyclopentanone + NADH + H+	81% conversion	Acinetobacter sp. RS1	2-butyl-cyclopentanone + NAD+	-	?
2-butylidene-cyclopentanone + NADPH + H+	-	Acinetobacter sp. RS1	2-butyl-cyclopentanone + NADP+	-	?
2-hetpylidene-cyclopentanone + NADH + H+	63% conversion	Acinetobacter sp. RS1	2-heptylcyclopentanone + NAD+	-	?
2-hetpylidene-cyclopentanone + NADPH + H+	82% conversion	Acinetobacter sp. RS1	2-heptylcyclopentanone + NADP+	-	?
2-hexylidene-cyclopentanone + NADH + H+	61% conversion	Acinetobacter sp. RS1	2-hexylcyclopentanone + NAD+	-	?
2-hexylidene-cyclopentanone + NADPH + H+	67% conversion	Acinetobacter sp. RS1	2-hexylcyclopentanone + NADP+	-	?
2-pentylidene-cyclopentanone + NADH + H+	100% conversion	Acinetobacter sp. RS1	2-pentyl-cyclopentanone + NAD+	-	?
2-pentylidene-cyclopentanone + NADPH + H+	-	Acinetobacter sp. RS1	2-pentyl-cyclopentanone + NADP+	-	?

Subunits

Subunits	Comment	Organism
?	x * 28500, SDS-PAGE	Acinetobacter sp. RS1

Synonyms

Synonyms	Comment	Organism
enoyl acyl carrier protein reductase	-	Acinetobacter sp. RS1
enoyl-ACP reductase	-	Acinetobacter sp. RS1
FabI	-	Acinetobacter sp. RS1

Cofactor

Cofactor	Comment	Organism	Structure
NADH	-	Acinetobacter sp. RS1
NADPH	-	Acinetobacter sp. RS1

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Release 2023.1 (January 2023)