Literature summary for 1.3.3.3 extracted from

Maytin, E.V.; Anand, S.; Riha, M.; Lohser, S.; Tellez, A.; Ishak, R.; Karpinski, L.; Sot, J.; Hu, B.; Denisyuk, A.; Davis, S.C.; Kyei, A.; Vidimos, A.
5-Fluorouracil enhances protoporphyrin IX accumulation and lesion clearance during photodynamic therapy of actinic keratoses A mechanism-based clinical trial (2018), Clin. Cancer Res., 24, 3026-3035 .

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Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
mitochondrion	-	Homo sapiens	5739	-

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
coproporphyrinogen III + O2 + 2 H+	Homo sapiens	-	protoporphyrinogen-IX + 2 CO2 + 2 H2O	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
coproporphyrinogen III + O2 + 2 H+	-	Homo sapiens	protoporphyrinogen-IX + 2 CO2 + 2 H2O	-	?

Synonyms

Synonyms	Comment	Organism
CPO	-	Homo sapiens

Expression

Organism	Comment	Expression
Homo sapiens	enzyme expression is induced by 5-fluorouracil	up

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Release 2023.1 (January 2023)