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Literature summary for 1.3.3.6 extracted from

  • Kim, S.; Kim, K.J.
    Structural insight into the substrate specificity of acyl-CoA oxidase1 from Yarrowia lipolytica for short-chain dicarboxylyl-CoAs (2018), Biochem. Biophys. Res. Commun., 495, 1628-1634 .
    View publication on PubMed
Search for more literature for 1.3.3.6

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21(DE3) cells Yarrowia lipolytica

Crystallization (Commentary)

Crystallization (Comment) Organism
hanging drop vapor diffusion method, using 12% (w/v) PEG3350, 0.2 M sodium citrate pH 5.0, and 2% (v/v) tacsimate pH 5.0 Yarrowia lipolytica

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
acyl-CoA + O2 Yarrowia lipolytica
-
 trans-2,3-dehydroacyl-CoA + H2O2
-
 ?
acyl-CoA + O2 Yarrowia lipolytica CLIB 122
-
 trans-2,3-dehydroacyl-CoA + H2O2
-
 ?

Organism

Organism UniProt Comment Textmining
Yarrowia lipolytica O74934
-
-
Yarrowia lipolytica CLIB 122 O74934
-
-

Purification (Commentary)

Purification (Comment) Organism
Ni-NTA agarose column chromatography and Superdex 200 gel filtration Yarrowia lipolytica

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acyl-CoA + O2
-
 Yarrowia lipolytica trans-2,3-dehydroacyl-CoA + H2O2
-
 ?
acyl-CoA + O2
-
 Yarrowia lipolytica CLIB 122 trans-2,3-dehydroacyl-CoA + H2O2
-
 ?
additional information the enzyme prefers short-chain dicarboxylyl-CoAs as a substrate Yarrowia lipolytica ?
-
-
additional information the enzyme prefers short-chain dicarboxylyl-CoAs as a substrate Yarrowia lipolytica CLIB 122 ?
-
-

Subunits

Subunits Comment Organism
homodimer x-ray crystallography Yarrowia lipolytica

Synonyms

Synonyms Comment Organism
ACOX1
-
 Yarrowia lipolytica

Cofactor

Cofactor Comment Organism Structure
FAD
-
 Yarrowia lipolytica