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Literature summary for 1.3.5.1 extracted from

  • Huang, K.T.; Dobrovic, A.; Fox, S.B.
    No evidence for promoter region methylation of the succinate dehydrogenase and fumarate hydratase tumour suppressor genes in breast cancer (2009), BMC Res. Notes, 2, 194.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
medicine no DNA methylation is identified in the promoter regions of the succinate dehydrogenase A, B, C, D and fumarate hydratase genes in 72 breast carcinomas and 10 breast cancer cell lines using methylation sensitive high resolution melting which detects both homogeneous and heterogeneous methylation, implying that that inactivation via DNA methylation of the promoter CpG islands of SDH and fumarate hydratase is unlikely to play a major role in sporadic breast carcinomas Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Synonyms

Synonyms Comment Organism
SDH
-
Homo sapiens
succinate dehydrogenase
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Homo sapiens