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Literature summary for 1.3.5.1 extracted from

  • Paranagama, M.P.; Sakamoto, K.; Amino, H.; Awano, M.; Miyoshi, H.; Kita, K.
    Contribution of the FAD and quinone binding sites to the production of reactive oxygen species from Ascaris suum mitochondrial complex II (2010), Mitochondrion, 10, 158-165.
    View publication on PubMed

Application

Application Comment Organism
molecular biology considering the conservation of amino acids crucial for the SQR activity and the high levels of ROS production from the mitochondrial complex II of the Ascaris suum adult worm together with the absence of complexes III and IV activities in its respiratory chain, it is a good model to examine the reactive oxygen species production from the mitochondrial complex II Ascaris suum

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion submitochondrial particles are prepared from frozen muscles of Ascaris suum adult female worms Ascaris suum 5739
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Organism

Organism UniProt Comment Textmining
Ascaris suum
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-
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Source Tissue

Source Tissue Comment Organism Textmining
muscle submitochondrial particles are prepared from frozen muscles of Ascaris suum adult female worms Ascaris suum
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Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
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the succinate-dependent reactive oxygen species production from the complex II of the Ascaris suum adult worm is significantly higher than that from the complex II of the L3 larvae Ascaris suum

Synonyms

Synonyms Comment Organism
SQR
-
Ascaris suum
succinate:quinone reductase
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Ascaris suum

Cofactor

Cofactor Comment Organism Structure
flavin adenine dinucleotide
-
Ascaris suum

General Information

General Information Comment Organism
physiological function using the submitochondrial particles from the adult worms and L3 larvae of the parasitic nematode Ascaris suum, it is shown that reactive oxygen species are produced from the flavin adenine dinucleotide-binding site as well as the quinone binding site in the mitochondrial complex II Ascaris suum