Activating Compound | Comment | Organism | Structure |
---|---|---|---|
adenosine 5'-[beta,gamma-imido]triphosphate | potent inhibitor | Thauera aromatica | |
adenosine 5'-[beta,gamma-methylene]triphosphate | inhibition only at high concentration, above 10 mM, in presence of 5 mM MgATP2- | Thauera aromatica |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
ADP | competitive with respect to ATP | Thauera aromatica |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.015 | - |
benzoyl-CoA | - |
Thauera aromatica | |
0.15 | - |
NH2OH | - |
Thauera aromatica |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Iron | contains two separate [2Fe-2S]clusters and two interacting [4Fe-4S]clusters | Thauera aromatica | |
Mg2+ | MgATP2- is required for activity | Thauera aromatica |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
Benzoyl-CoA + reduced acceptor + ATP | Thauera aromatica | key enzyme of anaerobic aromatic metabolism | ? | - |
? | |
Benzoyl-CoA + reduced acceptor + ATP | Thauera aromatica K172 | key enzyme of anaerobic aromatic metabolism | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Thauera aromatica | - |
- |
- |
Thauera aromatica K172 | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Thauera aromatica |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
benzoyl-CoA + reduced acceptor + ATP | - |
Thauera aromatica | cyclohexa-1,5-diene-1-carbonyl-CoA + acceptor + ADP + phosphate | - |
ir | |
benzoyl-CoA + reduced acceptor + ATP | - |
Thauera aromatica K172 | cyclohexa-1,5-diene-1-carbonyl-CoA + acceptor + ADP + phosphate | - |
ir | |
Benzoyl-CoA + reduced acceptor + ATP | key enzyme of anaerobic aromatic metabolism | Thauera aromatica | ? | - |
? | |
Benzoyl-CoA + reduced acceptor + ATP | key enzyme of anaerobic aromatic metabolism | Thauera aromatica K172 | ? | - |
? | |
NH2OH + ATP + H2O | - |
Thauera aromatica | ? | - |
? | |
NH2OH + ATP + H2O | - |
Thauera aromatica K172 | ? | - |
? |