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Literature summary for 1.3.8.1 extracted from

  • Kragh, P.M.; Pedersen, C.B.; Schmidt, S.P.; Winter, V.S.; Vajta, G.; Gregersen, N.; Bolund, L.; Corydon, T.J.
    Handling of human short-chain acyl-CoA dehydrogenase (SCAD) variant proteins in transgenic mice (2007), Mol. Genet. Metab., 91, 128-137.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Mus musculus Homo sapiens

Protein Variants

Protein Variants Comment Organism
G185S the mutant is not detected at protein level but shows high mRNA levels Homo sapiens
R83C unable to form tetramers, soluble mutant enzyme is not detected at steady-state Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
Homo sapiens 5739
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain wild type enzyme expression at protein level is only detected in brain Homo sapiens
-
liver
-
Homo sapiens
-
muscle
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
butyryl-CoA + electron acceptor
-
Homo sapiens 2-butenoyl-CoA + reduced acceptor
-
?

Synonyms

Synonyms Comment Organism
SCAD
-
Homo sapiens
short-chain acyl-CoA dehydrogenase
-
Homo sapiens