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Literature summary for 1.3.8.7 extracted from

  • Froemming, M.K.; Sames, D.
    Fluoromorphic Substrates for fatty acid metabolism: Highly sensitive probes for mammalian medium-chain acyl-CoA dehydrogenase (2006), Angew. Chem., 45, 637-642.
    View publication on PubMed

Application

Application Comment Organism
additional information development of fluorogenic and fluoromorphic probes for the enzyme as indicators for selective and sensetive detection of MCAD activity in tissue homogenates Rattus norvegicus
additional information development of fluorogenic and fluoromorphic probes for the enzyme as indicators for selective and sensetive detection of MCAD activity in tissue homogenates Sus scrofa

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0023
-
octanoyl-CoA
-
Sus scrofa
0.004
-
octanoyl-CoA
-
Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-
Sus scrofa
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information acts on a wide range of chain lengths (C16-C4) Rattus norvegicus ?
-
?
additional information acts on a wide range of chain lengths (C16-C4) Sus scrofa ?
-
?
octanoyl-CoA + acceptor
-
Rattus norvegicus 2-octenoyl-CoA + reduced acceptor
-
?
octanoyl-CoA + acceptor
-
Sus scrofa 2-octenoyl-CoA + reduced acceptor
-
?

Synonyms

Synonyms Comment Organism
general ACAD
-
Rattus norvegicus
general ACAD
-
Sus scrofa
MCAD
-
Rattus norvegicus
MCAD
-
Sus scrofa
medium-chain acyl-CoA dehydrogenase
-
Rattus norvegicus
medium-chain acyl-CoA dehydrogenase
-
Sus scrofa

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
19.6
-
octanoyl-CoA
-
Sus scrofa
35.7
-
octanoyl-CoA
-
Rattus norvegicus