Application | Comment | Organism |
---|---|---|
medicine | development of a durable gene therapy for VLCAD deficiency | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
into plasmid pCMV, expression in immune competent mice | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
additional information | VLCAD deficient fibroblasts and pCMV-hVLCAD transiently transfected VLCAD deficient fibroblasts, show antibody specificity, transfected fibroblasts show correction of the metabolic block as demonstrated by normalization of C14- and C16-acylcarnitine species in cell culture media and restoration of VLCAD activity in cells | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
70000 | - |
Western blot analysis | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
fibroblast | - |
Homo sapiens | - |
liver | - |
Homo sapiens | - |
muscle | - |
Homo sapiens | - |
Storage Stability | Organism |
---|---|
-20°C | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
palmitoyl-CoA + electron-transfer flavoprotein | - |
Homo sapiens | 2-hexadecenoyl-CoA + reduced electron-transfer flavoprotein | - |
? |
Synonyms | Comment | Organism |
---|---|---|
VLCAD | - |
Homo sapiens |