Literature summary for 1.3.99.5 extracted from

Li, Y.H.; Yang, Y.F.; Li, K.; Jin, L.L.; Yang, N.Y.; Kong, D.Y.
5 alpha-reductase and aromatase inhibitory constituents from Brassica rapa L. pollen (2009), Chem. Pharm. Bull., 57, 401-404.

Search for more literature for 1.3.99.5

Inhibitors

Inhibitors	Comment	Organism	Structure
linolenic acid	strong inhibition	Rattus norvegicus
Monolinolein	strong inhibition	Rattus norvegicus
additional information	screening of biologically active constituents from Brassica rapa pollen in supercritical CO2 fluid extract, overview. No inhibition by 24-methylenecholesterol linolenate, cycloeucalenol linolenate, 24-methylenecholesterol palmitate, cycloeucalenol, pollinastanol, 24-methylenecholesterol, palmitic acid, and monopalmitin	Rattus norvegicus

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
microsome	-	Rattus norvegicus	-	-

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
dihydrotestosterone + NADP+	Rattus norvegicus	the enzyme performs conversion of testosterone to dihydrotestosterone	testosterone + NADPH + H+	-	r

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
liver	-	Rattus norvegicus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
dihydrotestosterone + NADP+	-	Rattus norvegicus	testosterone + NADPH + H+	-	r
dihydrotestosterone + NADP+	the enzyme performs conversion of testosterone to dihydrotestosterone	Rattus norvegicus	testosterone + NADPH + H+	-	r

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Release 2023.1 (January 2023)