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Literature summary for 1.3.99.5 extracted from
- An overview on 5alpha-reductase inhibitors (2010), Steroids, 75, 109-153.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| (10bR)-8-chloro-4,10b-dimethyl-1,4,6,10b-tetrahydrobenzo[f]quinoline-3(2H)-thione | 13.2% inhibition at 0.04 mM | Homo sapiens |  |
| (10bR)-8-chloro-4,10b-dimethyl-1,5,6,10b-tetrahydrophenanthridin-3(2H)-one | - |
Homo sapiens | |
| (10bR)-8-chloro-4,5,10b-trimethyl-1,5,6,10b-tetrahydrophenanthridin-3(2H)-one | - |
Homo sapiens | |
| (10bR)-8-chloro-5,10b-dimethyl-1,5,6,10b-tetrahydrophenanthridin-3(2H)-one | - |
Homo sapiens | |
| (11aR)-7-(1-hydroxypropan-2-yl)-1,4a,6a-trimethylhexadecahydro-2H-indeno[5,4-f]quinolin-2-one | weak inhibition; weak inhibition | Homo sapiens | |
| (11aR)-7-(1-hydroxypropan-2-yl)-1,4a,6a-trimethyltetradecahydrocyclopenta[5,6]naphtho[2,1-d][1,3]oxazin-2(1H)-one | weak inhibition; weak inhibition | Homo sapiens | |
| (11aR)-7-(1-hydroxypropan-2-yl)-1,4a,6a-trimethyltetradecahydrocyclopenta[5,6]naphtho[2,1-d][1,3]oxazine-2(1H)-thione | weak inhibition; weak inhibition | Homo sapiens | |
| (11aR)-N,N-diethyl-1,4a,6a-trimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | weak inhibition; weak inhibition | Homo sapiens | |
| (16alpha,17beta)-17-hydroxy-16-methylandrost-4-en-3-one | - |
Homo sapiens | |
| (16alpha,17beta)-17-hydroxy-16-methylandrost-4-en-3-one | - |
Rattus norvegicus | |
| (16beta)-16-bromo-3,20-dioxopregna-1,4,6-trien-17-yl cyclopentylacetate | - |
Homo sapiens | |
| (16beta)-16-methyl-3,20-dioxopregna-1,4,6-trien-17-yl acetate | - |
Homo sapiens | |
| (16beta)-16-methyl-3,20-dioxopregna-1,4,6-trien-17-yl cyclopentylacetate | - |
Homo sapiens | |
| (16beta)-16-methyl-3,20-dioxopregna-1,4,6-trien-17-yl pentanoate | - |
Homo sapiens | |
| (16beta)-16-methyl-3,20-dioxopregna-4,6-dien-17-yl cyclopentylacetate | - |
Homo sapiens | |
| (16beta)-16-methyl-3,20-dioxopregna-4,6-dien-17-yl cyclopropanecarboxylate | - |
Homo sapiens | |
| (16beta)-16-methylandrost-4-ene-3,17-dione | - |
Homo sapiens | |
| (16beta)-16-methylandrost-4-ene-3,17-dione | - |
Rattus norvegicus | |
| (16beta)-17-hydroxy-16-methylpregna-1,4,6-triene-3,20-dione | - |
Homo sapiens | |
| (16beta)-6-bromo-16-methyl-3,20-dioxopregna-4,6-dien-17-yl acetate | - |
Homo sapiens | |
| (16beta)-6-bromo-17-(hex-1-en-2-yloxy)-16-methylpregna-4,6-diene-3,20-dione | - |
Homo sapiens | |
| (16beta)-6-chloro-16-methyl-17-[(1-phenylethenyl)oxy]pregna-4,6-diene-3,20-dione | - |
Homo sapiens | |
| (16beta)-6-chloro-16-methyl-3,20-dioxopregna-4,6-dien-17-yl acetate | - |
Homo sapiens | |
| (17beta)-16-ethyl-17-hydroxyandrost-4-en-3-one | - |
Homo sapiens | |
| (17beta)-16-ethyl-17-hydroxyandrost-4-en-3-one | - |
Rattus norvegicus | |
| (17beta)-17-(2-oxo-3-phenyl-1,3-oxazinan-6-yl)androst-4-en-3-one - 3-phenyl-1,3-oxazinan-2-one (1:1) | - |
Homo sapiens | |
| (17beta)-17-(propan-2-ylcarbamoyl)estra-1(10),2,4,6,8-pentaene-3-carboxylic acid | - |
Homo sapiens | |
| (17beta)-17-(propan-2-ylcarbamoyl)estra-1(10),2,4,6-tetraene-3-carboxylic acid | - |
Homo sapiens | |
| (17beta)-17-(propan-2-ylcarbamoyl)estra-1(10),2,4-triene-3-carboxylic acid | - |
Homo sapiens | |
| (17beta)-17-(propan-2-ylcarbamoyl)estra-1,3,5(10)-triene-3-sulfonic acid | - |
Homo sapiens | |
| (17beta)-17-[3-(4-bromophenyl)-2-oxo-1,3-oxazinan-6-yl]androst-4-en-3-one | - |
Homo sapiens | |
| (17beta)-17-[3-(4-chlorophenyl)-2-oxo-1,3-oxazinan-6-yl]androst-4-en-3-one | - |
Homo sapiens | |
| (17beta)-17-[3-(4-ethoxyphenyl)-2-oxo-1,3-oxazinan-6-yl]androst-4-en-3-one | - |
Homo sapiens | |
| (17beta)-17-[3-(4-ethylphenyl)-2-oxo-1,3-oxazinan-6-yl]androst-4-en-3-one | - |
Homo sapiens | |
| (17beta)-17-[3-(4-methoxyphenyl)-2-oxo-1,3-oxazinan-6-yl]androst-4-en-3-one | - |
Homo sapiens | |
| (17beta)-17-[di(propan-2-yl)carbamoyl]-4-fluoroandrost-3-ene-3-carboxylic acid | - |
Homo sapiens | |
| (17beta)-17-[di(propan-2-yl)carbamoyl]-4-methylandrosta-3,5-diene-3-carboxylic acid | - |
Homo sapiens | |
| (17beta)-17-[di(propan-2-yl)carbamoyl]-6-fluoroandrosta-3,5-diene-3-carboxylic acid | - |
Homo sapiens | |
| (17beta)-17-[di(propan-2-yl)carbamoyl]androst-3-ene-3-carboxylic acid | - |
Homo sapiens | |
| (17beta)-17-[di(propan-2-yl)carbamoyl]androsta-2,4,6-triene-3-carboxylic acid | - |
Homo sapiens | |
| (17beta)-17-[di(propan-2-yl)carbamoyl]androsta-3,5,11-triene-3-carboxylic acid | - |
Homo sapiens | |
| (17beta)-17-[di(propan-2-yl)carbamoyl]androsta-3,5-diene-3-carboxylic acid | - |
Homo sapiens | |
| (17beta)-17-[di(propan-2-yl)carbamoyl]estra-3,5-diene-3-carboxylic acid | - |
Homo sapiens | |
| (17beta)-2-chloro-17-(propan-2-ylcarbamoyl)estra-1(10),2,4-triene-3-carboxylic acid | - |
Homo sapiens | |
| (17beta)-3-(hydroxymethyl)-N-(propan-2-yl)androsta-3,5-diene-17-carboxamide | weak inhibitor; weak inhibitor | Homo sapiens | |
| (17beta)-3-(hydroxymethyl)-N-(propan-2-yl)androsta-3,5-diene-17-carboxamide | weak inhibitor | Rattus norvegicus | |
| (17beta)-3-nitro-N-(propan-2-yl)androst-3-ene-17-carboxamide | - |
Homo sapiens | |
| (17beta)-4-bromo-N-tert-butyl-3-oxoandrost-4-ene-17-carboxamide | - |
Homo sapiens | |
| (17beta)-4-fluoro-17-(propan-2-ylcarbamoyl)estra-1(10),2,4-triene-3-carboxylic acid | - |
Homo sapiens | |
| (17beta)-N-tert-butyl-3-oxo-4-sulfanylandrost-4-ene-17-carboxamide | - |
Homo sapiens | |
| (17beta)-N-tert-butyl-4-chloro-3-oxoandrost-4-ene-17-carboxamide | - |
Homo sapiens | |
| (17beta)-N-tert-butyl-4-cyano-3-oxoandrost-4-ene-17-carboxamide | - |
Homo sapiens | |
| (1R,4R,9aR,11aR)-4,9a,11a-trimethyl-1-((R)-6-methylheptan-2-yl)-3,3a,3b,4,5,8,9,9a,9b,10,11,11a-dodecahydro-1H-cyclopenta[i]phenanthridin-7(2H)-one | - |
Homo sapiens | |
| (1R,4S,9aR,11aR)-4,9a,11a-trimethyl-1-((R)-6-methylheptan-2-yl)-3,3a,3b,4,5,8,9,9a,9b,10,11,11a-dodecahydro-1H-cyclopenta[i]phenanthridin-7(2H)-one | - |
Homo sapiens | |
| (1R,9aR,11aR)-9a,11a-dimethyl-1-((R)-6-methylheptan-2-yl)-3,3a,3b,4,5,8,9,9a,9b,10,11,11a-dodecahydro-1H-cyclopenta[i]phenanthridin-7(2H)-one | - |
Homo sapiens | |
| (1S,8bS,10aS)-N,N-diethyl-8b,10a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,7,7a,8,8a,8b,8c,9,10,10a-hexadecahydrocyclopenta[i]cyclopropa[a]phenanthridine-1-carboxamide | - |
Homo sapiens | |
| (1S,9aR,11aR)-1-butyl-9a,11a-dimethyl-1,2,3,3a,3b,4,5,8,9,9a,9b,10,11,11a-tetradecahydro-7H-cyclopenta[i]phenanthridin-7-one | - |
Homo sapiens | |
| (1S,9aR,11aS)-1-(cyclohexylacetyl)-9a,11a-dimethyl-1,2,3,3a,3b,4,5,8,9,9a,9b,10,11,11a-tetradecahydro-7H-cyclopenta[i]phenanthridin-7-one | - |
Homo sapiens | |
| (1S,9aR,11aS)-6-bromo-9a,11a-dimethyl-7-oxo-N-(tricyclo[3.3.1.13,7]dec-1-yl)-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | - |
Homo sapiens | |
| (1S,9aR,11aS)-6-bromo-N,N-diethyl-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | - |
Homo sapiens | |
| (1S,9aR,11aS)-6-chloro-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | - |
Homo sapiens | |
| (1S,9aR,11aS)-6-chloro-N,N-diethyl-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | - |
Homo sapiens | |
| (1S,9aR,11aS)-9a,11a-dimethyl-1-nonanoyl-1,2,3,3a,3b,4,5,8,9,9a,9b,10,11,11a-tetradecahydro-7H-cyclopenta[i]phenanthridin-7-one | - |
Homo sapiens | |
| (1S,9aR,11aS)-9a,11a-dimethyl-N-(2-methylpropyl)-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | - |
Homo sapiens | |
| (1S,9aR,11aS)-N,N-diethyl-5,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | - |
Homo sapiens | |
| (1S,9aR,11aS)-N,N-diethyl-5,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,7,9a,9b,10,11,11a-dodecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | - |
Homo sapiens | |
| (1S,9aR,11aS)-N,N-diethyl-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | - |
Homo sapiens | |
| (1S,9aR,11aS)-N,N-diethyl-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | - |
Homo sapiens | |
| (1S,9aR,11aS)-N-(4,4'-di-tert-butylbiphenyl-3-yl)-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | - |
Homo sapiens | |
| (1S,9aR,11aS)-N-(4-tert-butylbiphenyl-3-yl)-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | - |
Homo sapiens | |
| (1S,9aR,11aS)-N-(5-bromo-2-tert-butylphenyl)-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | - |
Homo sapiens | |
| (1S,9aR,11aS)-N-(dicyclohexylmethyl)-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | - |
Homo sapiens | |
| (1S,9aR,11aS)-N-(diphenylmethyl)-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | - |
Homo sapiens | |
| (1S,9aR,11aS)-N-(diphenylmethyl)-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | - |
Homo sapiens | |
| (1S,9aR,11aS)-N-tert-butyl-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | - |
Homo sapiens | |
| (1S,9aR,11aS)-N-[1-(4-chlorophenyl)cyclobutyl]-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | - |
Homo sapiens | |
| (1S,9aR,11aS)-N-[2,5-bis(trifluoromethyl)phenyl]-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | - |
Homo sapiens | |
| (1S,9aR,11aS)-N-[2-tert-butyl-5-(trifluoromethyl)phenyl]-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | - |
Homo sapiens | |
| (1S,9aR,11aS)-N-[bis(4-chlorophenyl)methyl]-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | - |
Homo sapiens | |
| (1S,9aS,11aS)-N,N-diethyl-8,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,7,9a,9b,10,11,11a-dodecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | - |
Homo sapiens | |
| (20E)-20-(hydroxyimino)pregn-4-en-3-one | - |
Homo sapiens | |
| (20E)-20-(hydroxyimino)pregn-4-ene-3,6-dione | - |
Homo sapiens | |
| (20E)-20-(hydroxyimino)pregna-4,14,16-trien-3-one | - |
Homo sapiens | |
| (20E)-20-(hydroxyimino)pregna-4,16-dien-3-one | - |
Homo sapiens | |
| (21E)-21-(hydroxyimino)pregn-4-en-3-one | - |
Homo sapiens | |
| (22R,S)-N-(1,1,1-trifluoro-2-phenylprop-2-yl)-3-oxo-4-aza-5-androst-1-ene-17-carboxamide | i.e. FCE 28260; i.e. FCE 28260 | Homo sapiens | |
| (2R,3R,10aR,12aS)-2,10a,12a-trimethyl-1,8-dioxo-3-phenyl-1,2,3,4,4a,4b,8,10a,10b,11,12,12a-dodecahydrochrysen-2-yl acetate | - |
Homo sapiens | |
| (2R,3R,10aR,12aS)-2,10a,12a-trimethyl-1,8-dioxo-3-phenyl-1,2,3,4,4a,4b,8,9,10,10a,10b,11,12,12a-tetradecahydrochrysen-2-yl (2-fluorophenyl)acetate | - |
Homo sapiens | |
| (2R,3R,10aR,12aS)-2,10a,12a-trimethyl-1,8-dioxo-3-phenyl-1,2,3,4,4a,4b,8,9,10,10a,10b,11,12,12a-tetradecahydrochrysen-2-yl acetate | - |
Homo sapiens | |
| (2R,3R,10aR,12aS)-2-hydroxy-2,10a,12a-trimethyl-3-phenyl-3,4,4a,10a,10b,11,12,12a-octahydrochrysene-1,8(2H,4bH)-dione | - |
Homo sapiens | |
| (2R,3R,10aR,12aS)-2-hydroxy-2,10a,12a-trimethyl-3-phenyl-3,4,4a,9,10,10a,10b,11,12,12a-decahydrochrysene-1,8(2H,4bH)-dione | - |
Homo sapiens | |
| (2S,9aR,11aR)-2-(4-chlorophenoxy)-5,9a,11a-trimethyl-1,2,3,3a,3b,4,5,8,9,9a,9b,10,11,11a-tetradecahydro-7H-cyclopenta[i]phenanthridin-7-one | - |
Homo sapiens | |
| (3beta)-6,20-dioxopregna-4,16-dien-3-yl 3-bromopropanoate | - |
Homo sapiens | |
| (3beta)-6,20-dioxopregna-4,16-dien-3-yl 3-chloropropanoate | - |
Homo sapiens | |
| (3beta)-6,20-dioxopregna-4,16-dien-3-yl 3-iodopropanoate | - |
Homo sapiens | |
| (3beta)-6,20-dioxopregna-4,16-dien-3-yl propanoate | - |
Homo sapiens | |
| (3E,4aR,6aS,7S,11aR)-N,N-diethyl-3-(hydroxymethylidene)-1,4a,6a-trimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | - |
Homo sapiens | |
| (4-[[1-(dicyclohexylacetyl)piperidin-4-ylidene]methyl]-3-fluorophenyl)acetic acid | - |
Homo sapiens | |
| (4-[[1-(dicyclohexylacetyl)piperidin-4-ylidene]methyl]phenyl)acetic acid | - |
Homo sapiens | |
| (4aR,10bR)-4,10b-dimethyl-8-[(E)-2-phenylethenyl]-1,4,4a,5,6,10b-hexahydrobenzo[f]quinolin-3(2H)-one | - |
Homo sapiens | |
| (4aR,10bR)-4,8-dimethyl-1,4,4a,5,6,10b-hexahydrobenzo[f]quinolin-3(2H)-one | - |
Homo sapiens | |
| (4aR,10bR)-8-(furan-2-yl)-4,10b-dimethyl-1,4,4a,5,6,10b-hexahydrobenzo[f]quinolin-3(2H)-one | - |
Homo sapiens | |
| (4aR,10bR)-8-bromo-4-methyl-1,4,4a,5,6,10b-hexahydrobenzo[f]quinolin-3(2H)-one | - |
Homo sapiens | |
| (4aR,10bR)-8-chloro-1,4,4a,5,6,10b-hexahydrobenzo[f]quinolin-3(2H)-one | - |
Homo sapiens | |
| (4aR,10bR)-8-chloro-4,10b-dimethyl-1,4,4a,5,6,10b-hexahydrobenzo[f]quinolin-3(2H)-one | - |
Homo sapiens | |
| (4aR,10bR)-8-chloro-4,10b-dimethyl-1,4,4a,5,6,10b-hexahydrobenzo[f]quinoline-3(2H)-thione | 21.6% inhibition at 0.04 mM | Homo sapiens | |
| (4aR,10bR)-8-chloro-4-methyl-1,4,4a,5,6,10b-hexahydrobenzo[f]quinolin-3(2H)-one | i.e. LY191704; i.e. LY191704 | Homo sapiens | |
| (4aR,10bR)-8-fluoro-4-methyl-1,4,4a,5,6,10b-hexahydrobenzo[f]quinolin-3(2H)-one | - |
Homo sapiens | |
| (4aR,10bR)-8-[(E)-2-(isoquinolin-4-yl)ethenyl]-4,10b-dimethyl-1,4,4a,5,6,10b-hexahydrobenzo[f]quinolin-3(2H)-one | - |
Homo sapiens | |
| (4aR,5S,6aS,11aR)-N-(diphenylmethyl)-5-hydroxy-1,4a,6a,10-tetramethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | - |
Homo sapiens | |
| (4aR,5S,6aS,11aR)-N-(diphenylmethyl)-5-hydroxy-1,4a,6a,10-tetramethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | - |
Rattus norvegicus | |
| (4aR,5S,6aS,11aR)-N-(diphenylmethyl)-5-hydroxy-4a,6a,10-trimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | - |
Homo sapiens | |
| (4aR,5S,6aS,11aR)-N-(diphenylmethyl)-5-hydroxy-4a,6a,10-trimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | - |
Rattus norvegicus | |
| (4aR,6aR)-1,4a,6a,10-tetramethyl-7-(6-methylheptan-2-yl)-1,3,4,4a,4b,5,6,6a,7,8,9,9a,9b,10-tetradecahydro-2H-indeno[5,4-f]quinolin-2-one | - |
Homo sapiens | |
| (4aR,6aR)-1,4a,6a,10-tetramethyl-7-(6-methylheptan-2-yl)-1,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-2H-indeno[5,4-f]quinolin-2-one | - |
Homo sapiens | |
| (4aR,6aR)-1,4a,6a-trimethyl-7-(6-methylheptan-2-yl)-10-propyl-1,3,4,4a,4b,5,6,6a,7,8,9,9a,9b,11a-tetradecahydro-2H-indeno[5,4-f]quinolin-2-one | - |
Homo sapiens | |
| (4aR,6aR)-1,4a,6a-trimethyl-7-(6-methylheptan-2-yl)hexadecahydro-2H-indeno[5,4-f]quinolin-2-one | - |
Homo sapiens | |
| (4aR,6aR)-10-ethyl-1,4a,6a-trimethyl-7-(6-methylheptan-2-yl)hexadecahydro-2H-indeno[5,4-f]quinolin-2-one | - |
Homo sapiens | |
| (4aR,6aR)-4a,6a,10-trimethyl-7-(6-methylheptan-2-yl)-1,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-2H-indeno[5,4-f]quinolin-2-one | - |
Homo sapiens | |
| (4aR,6aS,11aR)-1,4a,6a,10-tetramethyl-2-oxo-N-(4,4,4-trifluoro-2-methyl-3-oxobutan-2-yl)-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | - |
Homo sapiens | |
| (4aR,6aS,11aR)-1,4a,6a,10-tetramethyl-2-oxo-N-(4,4,4-trifluoro-3-oxobutan-2-yl)-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | - |
Homo sapiens | |
| (4aR,6aS,11aR)-1,4a,6a,10-tetramethyl-N-(2-methyl-4-oxopentan-3-yl)-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | - |
Homo sapiens | |
| (4aR,6aS,11aR)-N-(2-cyanopropan-2-yl)-1,4a,6a,10-tetramethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | - |
Homo sapiens | |
| (4aR,6aS,11aR)-N-(2-cyanopropan-2-yl)-1,4a,6a,10-tetramethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | - |
Rattus norvegicus | |
| (4aR,6aS,7E,11aR)-7-(chloromethylidene)-1,6a-dimethylhexadecahydro-2H-indeno[5,4-f]quinolin-2-one | i.e. azaestranone II; i.e. azaestranone II | Homo sapiens | |
| (4aR,6aS,7S)-1,4a,6a-trimethyl-2,5-dioxo-N-phenyl-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | - |
Homo sapiens | |
| (4aR,6aS,7S)-1,4a,6a-trimethyl-2,5-dioxo-N-phenylhexadecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | - |
Homo sapiens | |
| (4aR,6aS,7S)-1,4a,6a-trimethyl-2,5-dioxo-N-[2-(trifluoromethyl)phenyl]-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | - |
Homo sapiens | |
| (4aR,6aS,7S)-4a,6a-dimethyl-2,5-dioxo-N-phenyl-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | - |
Homo sapiens | |
| (4aR,6aS,7S)-4a,6a-dimethyl-2,5-dioxo-N-phenylhexadecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | - |
Homo sapiens | |
| (4aR,6aS,7S)-N,1,4a,6a-tetramethyl-2,5-dioxo-N-phenyl-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | - |
Homo sapiens | |
| (4aR,6aS,7S)-N,4a,6a-trimethyl-2,5-dioxo-N-phenyl-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | - |
Homo sapiens | |
| (4aR,6aS,7S)-N-(2-chlorophenyl)-1,4a,6a-trimethyl-2,5-dioxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | - |
Homo sapiens | |
| (4aR,6aS,7S)-N-[2,5-bis(trifluoromethyl)phenyl]-1,4a,6a-trimethyl-2,5-dioxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | - |
Homo sapiens | |
| (4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-N-(3-methylbutanoyl)-2-oxo-N-(propan-2-yl)-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | - |
Homo sapiens | |
| (4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-N-(3-methylbutanoyl)-2-oxo-N-(propan-2-yl)-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | - |
Rattus norvegicus | |
| (4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-N-(3-methylbutanoyl)-2-oxo-N-(propan-2-yl)hexadecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | - |
Homo sapiens | |
| (4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-N-(3-methylbutanoyl)-2-oxo-N-(propan-2-yl)hexadecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | - |
Rattus norvegicus | |
| (4aR,6aS,7S,11aR)-4a,6a-dimethyl-2-oxo-N-(4,4,4-trifluoro-3-oxobutan-2-yl)-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | - |
Homo sapiens | |
| (4aR,6aS,7S,11aR)-4a,6a-dimethyl-4,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]isoquinolin-7-ol 2-oxide | - |
Homo sapiens | |
| (4aR,6aS,7S,11aR)-4a,6a-dimethyl-N-(3-methylbutanoyl)-2-oxo-N-(propan-2-yl)-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | - |
Homo sapiens | |
| (4aR,6aS,7S,11aR)-4a,6a-dimethyl-N-(3-methylbutanoyl)-2-oxo-N-(propan-2-yl)-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | - |
Rattus norvegicus | |
| (4aR,6aS,7S,11aR)-4a,6a-dimethyl-N-(3-methylbutanoyl)-2-oxo-N-(propan-2-yl)hexadecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | - |
Homo sapiens | |
| (4aR,6aS,7S,11aR)-4a,6a-dimethyl-N-(3-methylbutanoyl)-2-oxo-N-(propan-2-yl)hexadecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | - |
Rattus norvegicus | |
| (4aR,6aS,7S,11aR)-7-hydroxy-1,4a,6a-trimethylhexadecahydro-2H-indeno[5,4-f]quinolin-2-one | - |
Homo sapiens | |
| (4aR,6aS,7S,11aR)-N-(3,3-dimethylpentanoyl)-1,4a,6a-trimethyl-N-(2-methylbutan-2-yl)-2-oxohexadecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | - |
Homo sapiens | |
| (4aR,6aS,7S,11aR)-N-(3,3-dimethylpentanoyl)-1,4a,6a-trimethyl-N-(2-methylbutan-2-yl)-2-oxohexadecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | - |
Rattus norvegicus | |
| (4aR,6aS,7S,11aR)-N-(diphenylmethyl)-1,4a,6a-trimethyl-2,5-dioxohexadecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | - |
Homo sapiens | |
| (4aR,6aS,7S,11aR)-N-(diphenylmethyl)-1,4a,6a-trimethyl-2,5-dioxohexadecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | - |
Rattus norvegicus | |
| (4aR,6aS,7S,11aR)-N-(diphenylmethyl)-4a,6a-dimethyl-2,5-dioxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | - |
Homo sapiens | |
| (4aR,6aS,7S,11aR)-N-(diphenylmethyl)-4a,6a-dimethyl-2,5-dioxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | - |
Rattus norvegicus | |
| (4aR,6aS,7S,11aR)-N-(diphenylmethyl)-4a,6a-dimethyl-2,5-dioxohexadecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | - |
Homo sapiens | |
| (4aR,6aS,7S,11aR)-N-(diphenylmethyl)-4a,6a-dimethyl-2,5-dioxohexadecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | - |
Rattus norvegicus | |
| (4aR,6aS,7S,11aR)-N-cyclohexyl-N-(cyclohexylacetyl)-1,4a,6a-trimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | - |
Homo sapiens | |
| (4aR,6aS,7S,11aR)-N-cyclohexyl-N-(cyclohexylacetyl)-1,4a,6a-trimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | - |
Rattus norvegicus | |
| (4aR,6aS,7S,11aR)-N-[2,5-bis(trifluoromethyl)phenyl]-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | - |
Homo sapiens | |
| (4aR,7S)-8-ethyl-4a,7-dimethyl-10-methylidene-7-[(2S)-3-oxobutan-2-yl]-4,4a,4b,5,6,7,8,8a,9,10-decahydrophenanthren-2(3H)-one | - |
Homo sapiens | |
| (4aS,6aS,7S,11aR)-4a,6a-dimethyl-2,3,4,4a,5,6,6a,7,8,9,9a,10,11,11a-tetradecahydro-1H-indeno[5,4-f]isoquinolin-7-ol | - |
Homo sapiens | |
| (4aS,6aS,7S,11aS)-4a,6a-dimethyl-2-oxo-N,N-diphenyl-2,3,4,4a,5,6,6a,7,8,9,9a,10,11,11a-tetradecahydro-1H-indeno[4,5-h]isoquinoline-7-carboxamide | - |
Homo sapiens | |
| (4aS,6aS,7S,11aS)-4a,6a-dimethyl-2-oxo-N-phenyl-2,3,4,4a,5,6,6a,7,8,9,9a,10,11,11a-tetradecahydro-1H-indeno[4,5-h]isoquinoline-7-carboxamide | - |
Homo sapiens | |
| (4aS,6aS,7S,11aS)-4a,6a-dimethyl-2-oxo-N-[2-(trifluoromethyl)phenyl]-2,3,4,4a,5,6,6a,7,8,9,9a,10,11,11a-tetradecahydro-1H-indeno[4,5-h]isoquinoline-7-carboxamide | - |
Homo sapiens | |
| (4aS,6aS,7S,11aS)-4a,6a-dimethyl-4,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[4,5-h]isoquinolin-7-ol 3-oxide | - |
Homo sapiens | |
| (4aS,6aS,7S,11aS)-4a,6a-dimethyl-7-[methyl(phenyl)carbamoyl]-2-oxo-2,3,4,4a,5,6,6a,7,8,9,9a,10,11,11a-tetradecahydro-1H-indeno[4,5-h]isoquinolinium | - |
Homo sapiens | |
| (4aS,6aS,7S,11aS)-N,N-di(1H-indol-1-yl)-4a,6a-dimethyl-2-oxo-2,3,4,4a,5,6,6a,7,8,9,9a,10,11,11a-tetradecahydro-1H-indeno[4,5-h]isoquinoline-7-carboxamide | - |
Homo sapiens | |
| (4aS,6aS,7S,11aS)-N-(biphenyl-3-yl)-4a,6a-dimethyl-2-oxo-2,3,4,4a,5,6,6a,7,8,9,9a,10,11,11a-tetradecahydro-1H-indeno[4,5-h]isoquinoline-7-carboxamide | - |
Homo sapiens | |
| (4R)-5,10-seco-19-nor-pregna-4,5-diene-3,10,20-trione | a non-competitive and possibly irreversible inhibitor; a non-competitive and possibly irreversible inhibitor | Homo sapiens | |
| (4R)-5,10-seco-estra-4,5-diene-3,10,17-trione | a non-competitive and possibly irreversible inhibitor; a non-competitive and possibly irreversible inhibitor | Homo sapiens | |
| (5,20R)-4-diazo-21-hydroxy-20-methyl-pregn-6-en-3-one | i.e. RMI-18,341; i.e. RMI-18,341 | Homo sapiens | |
| (5alpha,6alpha)-20-oxo-5,6-epoxypregn-16-en-3-yl acetate | - |
Homo sapiens | |
| (5alpha17beta)-17-N,N-diethylcarbamoyl-4-methyl-4-aza-5-androstan-3-one | - |
Homo sapiens | |
| (5aR,7aS,8S,12aR)-5a,7a-dimethyl-2-oxooctadecahydrocyclopenta[5,6]naphtho[2,1-b]azepin-8-yl acetate | - |
Homo sapiens | |
| (5aR,9aR,11aS)-1-(3,3-dimethylbutanoyl)-6,9a,11a-trimethyl-1,2,3,3a,3b,4,5,5a,6,9a,9b,10,11,11a-tetradecahydro-7H-indolo[5,4-f]quinolin-7-one | - |
Homo sapiens | |
| (5aR,9aR,11aS)-1-(3,3-dimethylbutanoyl)-6,9a,11a-trimethylhexadecahydro-7H-indolo[5,4-f]quinolin-7-one | - |
Homo sapiens | |
| (5aR,9aR,11aS)-1-(3,3-dimethylbutanoyl)-9a,11a-dimethyl-1,2,3,3a,3b,4,5,5a,6,9a,9b,10,11,11a-tetradecahydro-7H-indolo[5,4-f]quinolin-7-one | - |
Homo sapiens | |
| (5aR,9aR,11aS)-1-(3,3-dimethylbutanoyl)-9a,11a-dimethylhexadecahydro-7H-indolo[5,4-f]quinolin-7-one | - |
Homo sapiens | |
| (6aR,7S,9aR,11aS)-7-hydroxy-1,9a,11a-trimethylhexadecahydro-2H-indeno[5,4-f]quinolin-2-one | - |
Homo sapiens | |
| (6aS,10aS,12aS)-1,10a,12a-trimethylhexadecahydronaphtho[2,1-f]quinoline-2,8-dione | - |
Homo sapiens | |
| (6aS,7S)-6a-methyl-N-(propan-2-yl)-5,6,6a,7,8,9,9a,9b-octahydro-4bH-indeno[5,4-f]isoquinoline-7-carboxamide 2-oxide | - |
Homo sapiens | |
| (6aS,7S)-N,N-diethyl-6a-methyl-5,6,6a,7,8,9,9a,9b-octahydro-4bH-indeno[5,4-f]isoquinoline-7-carboxamide 2-oxide | - |
Homo sapiens | |
| (6aS,8S,10aS,12aS)-8-hydroxy-1,10a,12a-trimethylhexadecahydronaphtho[2,1-f]quinolin-2(1H)-one | - |
Homo sapiens | |
| (6beta)-6-bromo-16-methyl-17-[(1-phenylethenyl)oxy]pregna-4,6-diene-3,20-dione | - |
Homo sapiens | |
| (7-chloro-3,4,4a,9-tetrahydrophenanthren-2-yl)phosphinic acid | - |
Homo sapiens | |
| (7aR,9aS,10S)-N,N-diethyl-7a,9a-dimethyl-5-oxo-1,2,3,5,6,7,7a,7b,8,9,9a,10,11,12,12a,12b-hexadecahydrobenzo[b]indeno[5,4-d]azepine-10-carboxamide | - |
Homo sapiens | |
| (7aS,8S,10aS,10bS)-N-tert-butyl-7a-methyl-2-oxo-2,3,4,5a,6,7,7a,8,9,10,10a,10b,11,12-tetradecahydrocyclopenta[f]pyrido[1,2-a]quinoline-8-carboxamide | - |
Homo sapiens | |
| (7aS,8S,12aR)-7a-methyl-8-(phenylamino)-5a,6,7,7a,8,9,10,10a,10b,11,12,12a-dodecahydrocyclopenta[f]pyrido[1,2-a]quinolin-2(1H)-one | - |
Homo sapiens | |
| (7aS,8S,12aR)-8-[benzyl(phenyl)amino]-7a-methyl-5a,6,7,7a,8,9,10,10a,10b,11,12,12a-dodecahydrocyclopenta[f]pyrido[1,2-a]quinolin-2(1H)-one | - |
Homo sapiens | |
| (8a,9b,10x,14x)-N-tert-butyl-3-oxoestr-4-ene-17-carboxamide | - |
Homo sapiens | |
| (8R,9aS,11aS)-1,9a,11a-trimethyl-2-oxo-N,N-di(propan-2-yl)hexadecahydro-1H-indeno[5,4-f]quinoline-8-carboxamide | - |
Homo sapiens | |
| (9aR,11aS)-1-(3,3-dimethylbutanoyl)-6,9a,11a-trimethyl-1,2,3,3a,3b,4,6,8,9,9a,9b,10,11,11a-tetradecahydro-7H-indolo[5,4-f]quinolin-7-one | - |
Homo sapiens | |
| (S)-4-[1-[4-[[1-(4-isobutylphenyl)butyl]oxy]benzoyl]indolizin-3-yl]-butyric acid | - |
Homo sapiens | |
| (S)-4-[1-[4-[[1-(4-isobutylphenyl)butyl]oxy]benzoyl]indolizin-3-yl]-butyric acid | - |
Rattus norvegicus | |
| (S)-4-[1-[4-[[1-(4-isobutylphenyl)butyl]oxy]benzoyl]indolizin-3-yl]butyric acid | - |
Homo sapiens | |
| (S)-4-[1-[4-[[1-(4-isobutylphenyl)butyl]oxy]benzoyl]indolizin-3-yl]butyric acid | - |
Rattus norvegicus | |
| 1,4,5,6-tetrahydrobenzo[f]quinolin-3(2H)-one | - |
Homo sapiens | |
| 1-(3-carboxypropyl)-4-[4-([[3-(2-methylpropyl)phenyl][4-(2-methylpropyl)phenyl]methyl]amino)benzoyl]-1H-pyrrole-3-carboxylic acid | - |
Homo sapiens | |
| 1-(3-carboxypropyl)-4-[4-([[3-(2-methylpropyl)phenyl][4-(2-methylpropyl)phenyl]methyl]amino)benzoyl]-1H-pyrrole-3-carboxylic acid | - |
Rattus norvegicus | |
| 1-cyclopropyl-3-ethyl-1-[(4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]urea | 20% inhibition at 100 nM in transfected SW-13 cells | Homo sapiens | |
| 1-cyclopropyl-3-methyl-1-[(4aR,6aS,7S,11aR)-1,4a,6a,10-tetramethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]urea | - |
Homo sapiens | |
| 1-cyclopropyl-3-phenyl-1-[(4aR,6aS,7S,11aR)-1,4a,6a,10-tetramethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]urea | - |
Homo sapiens | |
| 1-cyclopropyl-3-phenyl-1-[(4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]urea | 39.7% inhibition at 100 nM in transfected SW-13 cells; 56.3% inhibition at 100 nM in transfected SW-13 cells | Homo sapiens | |
| 1-methyl-5-phenylpiperidin-2-one | 13.5% inhibition at 0.04 mM | Homo sapiens | |
| 1-methyl-5-[4-(phenylacetyl)phenyl]pyridin-2(1H)-one | 61% inhibition at 0.010 mM | Homo sapiens | |
| 1-methyl-5-[4-[(E)-2-phenylethenyl]phenyl]piperidin-2-one | - |
Homo sapiens | |
| 1-methyl-5-[4-[(E)-phenyldiazenyl]phenyl]piperidin-2-one | - |
Homo sapiens | |
| 16,16-dimethylandrost-4-ene-3,17-dione | - |
Homo sapiens | |
| 16,16-dimethylandrost-4-ene-3,17-dione | - |
Rattus norvegicus | |
| 16-ethyl-17beta-hydroxy-4-estren-3-one | i.e. TSAA-291; i.e. TSAA-291 | Homo sapiens | |
| 16-ethyl-17beta-hydroxy-4-estren-3-one | i.e. TSAA-291, with purified nuclei from rat prostatic tissues | Rattus norvegicus | |
| 17-(2-cyclopentylethoxy)-6-methylidenepregn-4-ene-3,20-dione | - |
Homo sapiens | |
| 17-(3-cyclopentylpropoxy)-6-methylidenepregn-4-ene-3,20-dione | - |
Homo sapiens | |
| 17-hydroxy-6-methylidenepregn-4-ene-3,20-dione | - |
Homo sapiens | |
| 17-hydroxyestra-4,8-dien-3-one | - |
Homo sapiens | |
| 17-hydroxyestra-4,9(11)-dien-3-one | - |
Homo sapiens | |
| 17beta-(N-tert-butyl carbamoyl)-19-nor-10-aza-4-androsten-3-one | - |
Homo sapiens | |
| 17beta-(N-tert-butylcarbamoyl)-4-aza-5alpha-androst-1-en-3-one | - |
Homo sapiens | |
| 17beta-N,N-diethylcarbamoyl-4-methyl-4-aza-5alpha-androstan-3-one | - |
Homo sapiens | |
| 17beta-N,N-diethylcarbamoyl-4-methyl-4-aza-5alpha-androstan-3-one | - |
Rattus norvegicus | |
| 17beta-N-(2,5-bis(trifluoromethyl)-phenyl)-3-oxo-4-aza-5alpha-androst-1-ene-17-carboxamide | - |
Homo sapiens | |
| 2',3'-tetrahydrofuran-2'-spiro-17-(6-methylene-4-androsten-3-one) | i.e. L612,710; i.e. L612,710 | Homo sapiens | |
| 2',3'-tetrahydrofuran-2'-spiro-17-(6-methylene-4-androsten-3-one) | i.e. L612,710 | Rattus norvegicus | |
| 2-(trifluoromethyl)phenyl 4-methyl-3-oxo-2,3,5,6-tetrahydro-1H-pyrido[1,2-a]quinoline-8-carboxylate | 368% inhibition at 0.01 mM; 42% inhibition at 0.010 mM | Homo sapiens | |
| 2-fluorophenyl 4-methyl-3-oxo-2,3,5,6-tetrahydro-1H-pyrido[1,2-a]quinoline-8-carboxylate | 138% inhibition at 0.010 mM; 166% inhibition at 0.01 mM | Homo sapiens | |
| 2-methyl-N-phenyl-N-[(4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]propanamide | - |
Homo sapiens | |
| 2-oxo-8-(prop-2-en-1-yl)-2H-chromen-7-yl benzoate | - |
Homo sapiens | |
| 2-[4-(1,2-dimethyl-6-oxo-1,2,3,6-tetrahydropyridin-3-yl)phenoxy]-N-(propan-2-yl)acetamide | 3% inhibition at 0.010 mM | Homo sapiens | |
| 2-[4-(1-methyl-6-oxo-1,6-dihydropyridin-3-yl)phenoxy]-N-(prop-2-en-1-yl)acetamide | 6% inhibition at 0.010 mM | Homo sapiens | |
| 2-[4-(1-methyl-6-oxo-1,6-dihydropyridin-3-yl)phenoxy]-N-(propan-2-yl)acetamide | 8% inhibition at 0.010 mM | Homo sapiens | |
| 2-[4-(1-methyl-6-oxopiperidin-3-yl)phenoxy]-N-(propan-2-yl)acetamide | 6% inhibition at 0.010 mM | Homo sapiens | |
| 2-[[16-(acetylsulfanyl)hexadecanoyl]amino]ethyl (4Z)-6-([[4-(1-methyl-6-oxo-1,6-dihydropyridin-3-yl)phenoxy]acetyl]amino)hex-4-enoate | 43% inhibition at 0.010 mM | Homo sapiens | |
| 20-oxo-16,17-epoxypregn-5-en-3-yl acetate | - |
Homo sapiens | |
| 3,20-dioxopregn-4-en-17-yl (4-bromophenyl)carbamate | - |
Homo sapiens | |
| 3,20-dioxopregn-4-en-17-yl phenylcarbamate | - |
Homo sapiens | |
| 3,20-dioxopregna-4,6-dien-17-yl 4-bromobenzoate | - |
Homo sapiens | |
| 3,20-dioxopregna-4,6-dien-17-yl 4-fluorobenzoate | - |
Homo sapiens | |
| 3,20-dioxopregna-4,6-dien-17-yl benzoate | - |
Homo sapiens | |
| 3-(2,4-dimethoxyphenyl)-5-methoxy-8,8-dimethyl-4H,8H-pyrano[2,3-f]chromen-4-one | - |
Homo sapiens | |
| 3-(2,4-dimethoxyphenyl)-5-methoxy-8,8-dimethyl-4H,8H-pyrano[2,3-f]chromen-4-one | - |
Rattus norvegicus | |
| 3-(2-[[16-(acetylsulfanyl)hexadecanoyl]amino]ethoxy)propyl (4Z)-6-([[4-(1-methyl-6-oxo-1,6-dihydropyridin-3-yl)phenoxy]acetyl]amino)hex-4-enoate | 33% inhibition at 0.010 mM | Homo sapiens | |
| 3-butyl-1-cyclopropyl-1-[(4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinolin-7-yl]urea | 4.9% inhibition at 100 nM in transfected SW-13 cells | Homo sapiens | |
| 3-butyl-1-cyclopropyl-1-[(4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]urea | 46.3% inhibition at 100 nM in transfected SW-13 cells | Homo sapiens | |
| 3-chloro-4-(4-[N-(4-phenoxybenzyl)amino] phenoxy)benzoic acid | - |
Rattus norvegicus | |
| 3-chloro-4-(4-[N-(4-phenoxybenzyl)amino]phenoxy)benzoic acid | - |
Homo sapiens | |
| 3-chloro-4-([1-(4-methoxybenzyl)-2,3-dihydro-1H-indol-5-yl]oxy)benzoic acid | - |
Homo sapiens | |
| 3-chloro-4-([1-(4-phenoxybenzoyl)-1H-indol-5-yl]oxy)benzoic acid | - |
Homo sapiens | |
| 3-chloro-4-([1-(4-phenoxybenzyl)indolin-5-yl]oxy)benzoic acid | i.e. YM-36117; i.e. YM-36117 | Homo sapiens | |
| 3-chloro-4-([1-(4-phenoxybenzyl)indolin-5-yl]oxy)benzoic acid | i.e. YM-36117 | Rattus norvegicus | |
| 3-chloro-4-([1-(furan-2-ylmethyl)-2,3-dihydro-1H-indol-5-yl]oxy)benzoic acid | - |
Homo sapiens | |
| 3-chloro-4-[(1-(4-phenoxybenzoyl)-1H-indol-5-yl]oxy)benzoic acid | - |
Rattus norvegicus | |
| 3-chloro-4-[[1-(4-methoxybenzyl)-2,3-dihydro-1H-indol-5-yl]oxy]benzoic acid | - |
Homo sapiens | |
| 3-cyclohexyl-1-cyclopropyl-1-[(4aR,6aS,7S,11aR)-1,4a,6a,10-tetramethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]urea | - |
Homo sapiens | |
| 3-cyclohexyl-1-cyclopropyl-1-[(4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]urea | 48.7% inhibition at 100 nM in transfected SW-13 cells | Homo sapiens | |
| 3-fluorophenyl 4-methyl-3-oxo-2,3,5,6-tetrahydro-1H-pyrido[1,2-a]quinoline-8-carboxylate | 134% inhibition at 0.01 mM; 160% inhibition at 0.010 mM | Homo sapiens | |
| 3-hydroxy-16,17-epoxypregn-5-en-20-one | - |
Homo sapiens | |
| 3-[2,4-bis(benzyloxy)phenyl]-5-methoxy-8,8-dimethyl-4H,8H-pyrano[2,3-f]chromen-4-one | - |
Homo sapiens | |
| 3-[2,4-bis(benzyloxy)phenyl]-5-methoxy-8,8-dimethyl-4H,8H-pyrano[2,3-f]chromen-4-one | - |
Rattus norvegicus | |
| 3-[2,4-bis(benzyloxy)phenyl]-5-methoxy-8,8-dimethyl-8,9-dihydro-4H,10H-pyrano[2,3-f]chromene-4,10-dione | - |
Homo sapiens | |
| 3-[2,4-bis(benzyloxy)phenyl]-5-methoxy-8,8-dimethyl-8,9-dihydro-4H,10H-pyrano[2,3-f]chromene-4,10-dione | - |
Rattus norvegicus | |
| 4'-(tricyclo[3.3.1.13,7]dec-2-ylcarbamoyl)biphenyl-4-carboxylic acid | - |
Homo sapiens | |
| 4'-(tricyclo[3.3.1.13,7]dec-2-ylcarbamoyl)biphenyl-4-carboxylic acid | - |
Rattus norvegicus | |
| 4'-[2-[di(propan-2-yl)amino]-2-oxoethoxy]-3',5'-di(propan-2-yl)biphenyl-4-carboxylic acid | - |
Homo sapiens | |
| 4'-[2-[di(propan-2-yl)amino]-2-oxoethoxy]-3'-fluoro-5'-nitrobiphenyl-4-carboxylic acid | - |
Homo sapiens | |
| 4,4a,5,6,7,8,9,10-octahydro-3H-pyrido[1,2-a]quinolin-3-one | - |
Homo sapiens | |
| 4,8-dimethyl-1,2,5,6-tetrahydro-3H-pyrido[1,2-a]quinolin-3-one | - |
Homo sapiens | |
| 4-(1-benzyl-1H-indol-5-yl)benzoic acid | - |
Homo sapiens | |
| 4-(2-[1-(4,4'-dipropylbenzhydryl)indole-5-carboxamido]phenoxy)butyric acid | - |
Homo sapiens | |
| 4-(2-[1-(4,4'-dipropylbenzhydryl)indole-5-carboxamido]phenoxy)butyric acid | - |
Rattus norvegicus | |
| 4-(2-[[(2E)-3-[1-[bis(4-fluorophenyl)methyl]-1H-indol-5-yl]pent-2-enoyl]amino]phenoxy)butanoic acid | i.e. KF20405; i.e. KF20405 | Homo sapiens | |
| 4-(3-(4-(N-methylacetamido)phenyl) pentan-3-yl) phenyldibenzylcarbamate | - |
Homo sapiens | |
| 4-(3-[[2,2-bis(4-chlorophenyl)-1,3-benzodioxol-5-yl]carbonyl]-2-methyl-1H-indol-1-yl)butanoic acid | - |
Homo sapiens | |
| 4-(4-benzoylphenoxy)benzoic acid | - |
Homo sapiens | |
| 4-(biphenyl-4-yloxy)-2-chlorobenzoic acid | - |
Homo sapiens | |
| 4-(biphenyl-4-yloxy)-2-fluorobenzoic acid | - |
Homo sapiens | |
| 4-(biphenyl-4-yloxy)-3-methoxybenzoic acid | - |
Homo sapiens | |
| 4-(methoxycarbonyl)phenyl 4-methyl-3-oxo-2,3,5,6-tetrahydro-1H-pyrido[1,2-a]quinoline-8-carboxylate | 129% inhibition at 0.010 mM; 584% inhibition at 0.01 mM | Homo sapiens | |
| 4-androsten-3-one-17-carboxylic acid | competitive | Homo sapiens | |
| 4-bromo-3,20-dioxopregn-4-en-17-yl 4-chlorobenzoate | - |
Homo sapiens | |
| 4-bromo-3,20-dioxopregn-4-en-17-yl 4-fluorobenzoate | - |
Homo sapiens | |
| 4-bromo-3,20-dioxopregna-1,4-dien-17-yl acetate | - |
Homo sapiens | |
| 4-cyanoprogesterone | - |
Homo sapiens | |
| 4-cyanoprogesterone | - |
Rattus norvegicus | |
| 4-fluorophenyl 4-methyl-3-oxo-2,3,5,6-tetrahydro-1H-pyrido[1,2-a]quinoline-8-carboxylate | 119% inhibition at 0.01 mM; 93% inhibition at 0.010 mM | Homo sapiens | |
| 4-methylphenyl 4-methyl-3-oxo-2,3,5,6-tetrahydro-1H-pyrido[1,2-a]quinoline-8-carboxylate | 102% inhibition at 0.010 mM; 553% inhibition at 0.01 mM | Homo sapiens | |
| 4-trifluoromethyl-N-(tert-butyl)-4-androsten-17beta-carboxamide | - |
Homo sapiens | |
| 4-[(1-benzyl-1H-indol-5-yl)oxy]-3-chlorobenzoic acid | - |
Homo sapiens | |
| 4-[(1-benzyl-1H-indol-5-yl)oxy]-3-chlorobenzoic acid | - |
Rattus norvegicus | |
| 4-[1-(6,6-dimethyl-6H-dibenzo[b,d]pyran-3-yl)methylindol-3-yl]-butyric acid | i.e. FR119680; i.e. FR119680 | Homo sapiens | |
| 4-[1-(6,6-dimethyl-6H-dibenzo[b,d]pyran-3-yl)methylindol-3-yl]-butyric acid | i.e. FR119680 | Rattus norvegicus | |
| 4-[2-(1-methyl-6-oxopiperidin-3-yl)ethyl]-N,N-di(propan-2-yl)benzamide | - |
Homo sapiens | |
| 4-[2-(1-methyl-6-oxopiperidin-3-yl)ethyl]-N,N-di(propan-2-yl)benzamide | - |
Rattus norvegicus | |
| 4-[2-(5-[[bis(4-fluorophenyl)methyl]carbamoyl]-1-benzofuran-2-yl)phenoxy]butanoic acid | - |
Homo sapiens | |
| 4-[2-(6-[[bis(4-fluorophenyl)methyl]carbamoyl]-1-benzofuran-2-yl)phenoxy]butanoic acid | - |
Homo sapiens | |
| 4-[2-(6-[[bis(4-fluorophenyl)methyl]carbamoyl]-1-benzofuran-2-yl)phenoxy]butanoic acid | - |
Rattus norvegicus | |
| 4-[3-(1-methyl-6-oxopiperidin-3-yl)butan-2-yl]-N,N-di(propan-2-yl)benzamide | - |
Homo sapiens | |
| 4-[3-(1-methyl-6-oxopiperidin-3-yl)butan-2-yl]-N,N-di(propan-2-yl)benzamide | - |
Rattus norvegicus | |
| 4-[3-(4-[(1R)-1-[4-(2-methylpropyl)phenyl]ethoxy]benzoyl)-1H-indol-1-yl]butanoic acid | - |
Homo sapiens | |
| 4-[3-([(2R)-2-methyl-2-[4-(2-methylpropyl)phenyl]-1,3-benzodioxol-5-yl]carbonyl)-1H-indol-1-yl]butanoic acid | - |
Homo sapiens | |
| 4-[3-ethyl-4-[4-([[3-(2-methylpropyl)phenyl][4-(2-methylpropyl)phenyl]methyl]amino)benzoyl]-1H-pyrrol-1-yl]butanoic acid | - |
Homo sapiens | |
| 4-[3-ethyl-4-[4-([[3-(2-methylpropyl)phenyl][4-(2-methylpropyl)phenyl]methyl]amino)benzoyl]-1H-pyrrol-1-yl]butanoic acid | - |
Rattus norvegicus | |
| 4-[3-[3-([[3-(2-methylpropyl)phenyl][4-(2-methylpropyl)phenyl]methyl]amino)benzoyl]-4-(propan-2-yl)-1H-pyrrol-1-yl]butanoic acid | - |
Homo sapiens | |
| 4-[3-[3-([[3-(2-methylpropyl)phenyl][4-(2-methylpropyl)phenyl]methyl]amino)benzoyl]-4-(propan-2-yl)-1H-pyrrol-1-yl]butanoic acid | - |
Rattus norvegicus | |
| 4-[3-[3-[bis (4-isobutylphenyl)methyl amino] benzoyl]-lH-indol-l-yl] butyric acid | i.e. FK-143 | Homo sapiens | |
| 4-[3-[3-[bis (4-isobutylphenyl)methylamino]benzoyl]-lH-indol-l-yl] butyric acid | i.e. FK-143 | Homo sapiens | |
| 4-[3-[3-[bis (4-isobutylphenyl)methylamino]benzoyl]-lH-indol-l-yl] butyric acid | i.e. FK-143 | Rattus norvegicus | |
| 4-[3-[3-[bis(4-isobutylphenyl)methylamino]benzoyl]-lH-indol-l-yl]butyric acid | - |
Homo sapiens | |
| 4-[3-[3-[bis(4-isobutylphenyl)methylamino]benzoyl]-lH-indol-l-yl]butyric acid | - |
Rattus norvegicus | |
| 4-[3-[4-([[3-(2-methylpropyl)phenyl][4-(2-methylpropyl)phenyl]methyl]amino)benzoyl]-1H-pyrrol-1-yl]butanoic acid | - |
Homo sapiens | |
| 4-[3-[4-([[3-(2-methylpropyl)phenyl][4-(2-methylpropyl)phenyl]methyl]amino)benzoyl]-1H-pyrrol-1-yl]butanoic acid | - |
Rattus norvegicus | |
| 4-[3-[4-([[3-(2-methylpropyl)phenyl][4-(2-methylpropyl)phenyl]methyl]amino)benzoyl]-4-(propan-2-yl)-1H-pyrrol-1-yl]butanoic acid | - |
Homo sapiens | |
| 4-[3-[4-([[3-(2-methylpropyl)phenyl][4-(2-methylpropyl)phenyl]methyl]amino)benzoyl]-4-(propan-2-yl)-1H-pyrrol-1-yl]butanoic acid | - |
Rattus norvegicus | |
| 4-[4-(4-methylbenzoyl)phenoxy]benzoic acid | - |
Homo sapiens | |
| 4-[4-(tricyclo[3.3.1.13,7]dec-2-ylcarbamoyl)phenoxy]benzoic acid | - |
Homo sapiens | |
| 4-[4-(tricyclo[3.3.1.13,7]dec-2-ylcarbamoyl)phenoxy]benzoic acid | - |
Rattus norvegicus | |
| 4-[4-[di(propan-2-yl)carbamoyl]-2-ethylphenyl]cyclohex-1-ene-1-carboxylic acid | - |
Homo sapiens | |
| 4-[[1-(2-propylpentanoyl)piperidin-4-ylidene]methyl]benzoic acid | - |
Homo sapiens | |
| 4-[[1-(2-propylpentanoyl)piperidin-4-ylidene]methyl]benzoic acid | type II isozyme | Rattus norvegicus | |
| 4-[[1-(biphenyl-4-ylcarbamoyl)piperidin-4-ylidene]methyl]benzoic acid | - |
Homo sapiens | |
| 4-[[1-(biphenyl-4-ylcarbamoyl)piperidin-4-ylidene]methyl]benzoic acid | type II isozyme; type I isozyme | Rattus norvegicus | |
| 4-[[1-(dicyclohexylacetyl)piperidin-4-ylidene]methyl]-3-fluorobenzoic acid | - |
Homo sapiens | |
| 4-[[1-(dicyclohexylacetyl)piperidin-4-ylidene]methyl]benzoic acid | - |
Homo sapiens | |
| 4-[[1-(dicyclohexylacetyl)piperidin-4-ylidene]methyl]benzoic acid | type II isozyme; type I isozyme | Rattus norvegicus | |
| 4-[[1-(diphenylacetyl)piperidin-4-ylidene]methyl]benzoic acid | - |
Homo sapiens | |
| 4-[[1-(diphenylacetyl)piperidin-4-ylidene]methyl]benzoic acid | type II isozyme; type I isozyme | Rattus norvegicus | |
| 5-(2-ethyl-3-[3-[(4-hexylundecyl)amino]benzoyl]-1H-pyrrol-1-yl)pentanoate | - |
Homo sapiens | |
| 5-(2-ethyl-3-[3-[(4-hexylundecyl)amino]benzoyl]-1H-pyrrol-1-yl)pentanoate | - |
Rattus norvegicus | |
| 5-(4-chlorophenyl)-1-methylpiperidin-2-one | - |
Homo sapiens | |
| 5-(4-chlorophenyl)-1-methylpiperidine-2-thione | 14% inhibition at 0.04 mM | Homo sapiens | |
| 5-(benzyloxy)-1H-indole-2-carboxylic acid | - |
Homo sapiens | |
| 5-bromo-N-pentyl-N-[(4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]pentanamide | - |
Homo sapiens | |
| 6,20-dioxopregn-4-en-3-yl 4-bromobenzoate | - |
Homo sapiens | |
| 6,20-dioxopregn-4-en-3-yl 4-fluorobenzoate | - |
Homo sapiens | |
| 6,20-dioxopregn-4-en-3-yl 5-chloropentanoate | - |
Homo sapiens | |
| 6,20-dioxopregna-4,16-dien-3-yl 4-bromobenzoate | - |
Homo sapiens | |
| 6,20-dioxopregna-4,16-dien-3-yl 4-fluorobenzoate | - |
Homo sapiens | |
| 6,20-dioxopregna-4,16-dien-3-yl 4-methylbenzoate | - |
Homo sapiens | |
| 6,20-dioxopregna-4,16-dien-3-yl acetate | - |
Homo sapiens | |
| 6,20-dioxopregna-4,16-dien-3-yl benzoate | - |
Homo sapiens | |
| 6,8-dimethyl-1,2,5,6-tetrahydro-3H-pyrido[1,2-a]quinolin-3-one | - |
Homo sapiens | |
| 6-(benzyloxy)-5-methoxy-1-methyl-1H-indole-2-carboxylic acid | - |
Homo sapiens | |
| 6-([5-[(1R,4aR,6aR,7R,11aR)-1,4a,6a-trimethyl-1-oxidohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]hexanoyl]amino)hexanoic acid | - |
Homo sapiens | |
| 6-([5-[(1S,4aR,6aR,7R,11aR)-1,4a,6a-trimethyl-1-oxidohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]hexanoyl]amino)hexanoic acid | - |
Homo sapiens | |
| 6-bromo-3,20-dioxopregna-4,6-dien-17-yl acetate | i.e. ONO-3806; i.e. ONO-3806 | Homo sapiens | |
| 6-chloro-3,20-dioxopregna-4,6-dien-17-yl 4-bromobenzoate | - |
Homo sapiens | |
| 6-chloro-3,20-dioxopregna-4,6-dien-17-yl 4-fluorobenzoate | - |
Homo sapiens | |
| 6-chloro-3,20-dioxopregna-4,6-dien-17-yl benzoate | - |
Homo sapiens | |
| 6-hydroxy-9,10-dimethoxy-3,3-dimethyl-3H-chromeno[3,4-b]pyrano[2,3-h]chromen-7(13H)-one | - |
Homo sapiens | |
| 6-hydroxy-9,10-dimethoxy-3,3-dimethyl-3H-chromeno[3,4-b]pyrano[2,3-h]chromen-7(13H)-one | - |
Rattus norvegicus | |
| 6-methylidene-3,20-dioxopregn-4-en-17-yl 4-bromobenzoate | - |
Homo sapiens | |
| 6-[(1R,4aR,6aR,7R,11aR)-7-[6-[(4-cyanobenzyl)oxy]hexan-2-yl]-4a,6a-dimethyl-1-oxidohexadecahydro-1H-indeno[5,4-f]quinolin-1-yl]hexanoic acid | - |
Homo sapiens | |
| 6-[(1S,4aR,6aR,7R,11aR)-7-[6-[(4-cyanobenzyl)oxy]hexan-2-yl]-4a,6a-dimethyl-1-oxidohexadecahydro-1H-indeno[5,4-f]quinolin-1-yl]hexanoic acid | - |
Homo sapiens | |
| 6-[3-(N,N-dicyclohexylaminocarbonyl) phenyl]-3,4-dihydro-naphthalene-2-carboxylate | - |
Homo sapiens | |
| 6-[3-(N,N-dicyclohexylaminocarbonyl)phenyl]-3,4-dihydro-naphthalene-2-carboxylic acid | - |
Homo sapiens | |
| 6-[4-(N,N-diisopropylamino-carbonyl) phenyl]naphthalene-2-carboxylic acid | - |
Homo sapiens | |
| 6-[4-(N,N-diisopropylamino-carbonyl)phenyl]naphthalene-2-carboxylic acid | uncompetitive | Homo sapiens | |
| 6-[4-(N,N-diisopropylcarbamoyl) phenyl]-1H-quinolin-2-one | competitive inhibitor | Homo sapiens | |
| 6-[4-(N,N-diisopropylcarbamoyl) phenyl]-N-methyl-quinolin-2-one | - |
Homo sapiens | |
| 6-[4-[di(propan-2-yl)carbamoyl]phenyl]-3,4-dihydronaphthalene-2-carboxylic acid | - |
Homo sapiens | |
| 7-bromo-9,10-dihydrophenanthrene-2-carboxylic acid | - |
Homo sapiens | |
| 7-chloro-3,4,4a,9-tetrahydrophenanthrene-2-carboxylic acid | - |
Homo sapiens | |
| 7-chloro-9,10-dihydrophenanthrene-2-carboxylic acid | - |
Homo sapiens | |
| 7-[(3-methylbut-2-en-1-yl)oxy]-2H-chromen-2-one | - |
Homo sapiens | |
| 7-[(E)-2-phenylethenyl]-9,10-dihydrophenanthrene-2-carboxylic acid | - |
Homo sapiens | |
| 8-allyl-7-hydroxycoumarin | - |
Homo sapiens | |
| 8-bromo-4-methyl-1,4,5,6-tetrahydrobenzo[f]quinolin-3(2H)-one | - |
Homo sapiens | |
| 8-chloro-1,2,5,6,6a,7,8,9,10,10a-decahydro-3H-pyrido[1,2-a]quinolin-3-one | - |
Homo sapiens | |
| 8-chloro-1,2,5,6,7,8,9,10-octahydro-3H-pyrido[1,2-a]quinolin-3-one | - |
Homo sapiens | |
| 8-chloro-1,2,5,6-tetrahydro-3H-pyrido[1,2-a]quinolin-3-one | - |
Homo sapiens | |
| 8-chloro-1,4,5,6-tetrahydrobenzo[f]quinolin-3(2H)-one | - |
Homo sapiens | |
| 8-chloro-1-methyl-1,2,5,6-tetrahydro-3H-pyrido[1,2-a]quinolin-3-one | - |
Homo sapiens | |
| 8-chloro-4,4a,5,6-tetrahydro-3H-pyrido[1,2-a]quinolin-3-one | - |
Homo sapiens | |
| 8-chloro-4,6-dimethyl-4,4a,5,6-tetrahydro-3H-pyrido[1,2-a]quinolin-3-one | - |
Homo sapiens | |
| 8-chloro-4-methyl-1,4,5,6-tetrahydrobenzo[f]quinolin-3(2H)-one | - |
Homo sapiens | |
| 8-chloro-4-methyl-4,4a,5,6-tetrahydro-3H-pyrido[1,2-a]quinolin-3-one | - |
Homo sapiens | |
| 8-methyl-1,2,5,6-tetrahydro-3H-pyrido[1,2-a]quinolin-3-one | - |
Homo sapiens | |
| 9,10-dihydrophenanthrene-2-carboxylic acid | - |
Homo sapiens | |
| androst-4-ene-3,17-dione | - |
Homo sapiens | |
| androst-4-ene-3,17-dione | - |
Rattus norvegicus | |
| dutasteride | i.e. 17beta-N-(2,5-bis(trifluoromethyl)-phenyl)-3-oxo-4-aza-5alpha-androst-1-ene-17-carboxamide, a competitive inhibitor of both 5alpha-reductase type I and type II isozymes, reduces DHT levels over 90% following 1 year of oral administration; i.e. 17beta-N-(2,5-bis(trifluoromethyl)-phenyl)-3-oxo-4-aza-5alpha-androst-1-ene-17-carboxamide, a competitive inhibitor of both 5alpha-reductase type I and type II isozymes, reduces DHT levels over 90% following 1 year of oral administration | Homo sapiens | |
| epristeride | - |
Homo sapiens | |
| estra-4,8-diene-3,17-dione | - |
Homo sapiens | |
| estra-4,9(11)-diene-3,17-dione | - |
Homo sapiens | |
| ethyl 4-[2-[([1-[bis(4-propylphenyl)methyl]-1H-benzimidazol-5-yl]carbonyl)amino]phenoxy]butanoate | - |
Homo sapiens | |
| ethyl 4-[2-[([1-[bis(4-propylphenyl)methyl]-1H-benzimidazol-5-yl]carbonyl)amino]phenoxy]butanoate | - |
Rattus norvegicus | |
| finasteride | i.e. 17beta-(N-tert-butylcarbamoyl)-4-aza-5alpha-androst-1-en-3-one, decreases the prostatic DHT level by 70-90% and reduces the prostatic size, inhibition mechanism, detailed overview; i.e. 17beta-(N-tert-butylcarbamoyl)-4-aza-5alpha-androst-1-en-3-one, decreases the prostatic dihydrotestosterone level by 70-90% and reduces the prostatic size, inhibition mechanism, detailed overview | Homo sapiens | |
| methyl (1S,9aR,11aS)-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxylate | - |
Homo sapiens | |
| methyl(1S,9aR,11aS)-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxylate | - |
Homo sapiens | |
| additional information | steroidal and non-steroidal 5alpha-reductase inhibitors as they inhibit the conversion of testosterone to 5alpha-dihydrotestosterone, detailed overview. 4-Aza, 6-aza and charged 3-substituents derivatives are highly selective for type II enzyme. Potent inhibitors of steroid 5alpha-reductase are found among the transition state analogues as molecules mimicking the transition state of the enzymatic processes exhibit a greater binding to the enzyme and hence produce greater inhibition. The enzyme 5alpha-reductase binds the 3-keto-DELTA4 steroids in such a way that the carbonyl group is brought into vicinity of a positively charged centre on the enzyme whereby the conjugated ketone becomes activated. Poor inhibition by (4aS,6aS,7S,11aS)-7-hydroxy-4a,6a-dimethylhexadecahydro-2H-indeno[4,5-h]isoquinolin-2-one, (4aS,6aS,7S,11aS)-4a,6a-dimethylhexadecahydro-1H-indeno[4,5-h]isoquinolin-7-ol, and (4aS,6aS,7S,11aR)-7-hydroxy-4a,6a-dimethyl-1,2,4,4a,5,6,6a,7,8,9,9a,10,11,11a-tetradecahydro-3H-indeno[5,4-f]isoquinolin-3-one. No inhibition (17E)-17-(hydroxyimino)androst-5-en-3-ol, (20Z)-20-(hydroxyimino)pregn-5-en-3-ol, (20Z)-20-(hydroxyimino)pregna-5,16-dien-3-ol, 20-(hydroxyimino)pregna-5,14-dien-3-ol, and 20-(hydroxyimino)pregna-5,14,16-trien-3-ol, and by 2-[4-(1-methyl-6-oxo-1,6-dihydropyridin-3-yl)phenoxy]-N-(propan-2-yl)acetamide, 2-[4-(1-methyl-6-oxo-1,6-dihydropyridin-3-yl)phenoxy]-N-(prop-2-en-1-yl)acetamide, 2-[4-(1-methyl-6-oxopiperidin-3-yl)phenoxy]-N-(propan-2-yl)acetamide, 2-[4-(1,2-dimethyl-6-oxo-1,2,3,6-tetrahydropyridin-3-yl)phenoxy]-N-(propan-2-yl)acetamide, 1-methyl-5-[4-(phenylacetyl)phenyl]pyridin-2(1H)-one, 2-[[16-(acetylsulfanyl)hexadecanoyl]amino]ethyl (4Z)-6-([[4-(1-methyl-6-oxo-1,6-dihydropyridin-3-yl)phenoxy]acetyl]amino)hex-4-enoate, and 3-(2-[[16-(acetylsulfanyl)hexadecanoyl]amino]ethoxy)propyl (4Z)-6-([[4-(1-methyl-6-oxo-1,6-dihydropyridin-3-yl)phenoxy]acetyl]amino)hex-4-enoate, as well as 8-chloro-1,2,5,6,7,8,9,10-octahydro-3H-pyrido[1,2-a]quinolin-3-one and 8-chloro-1,2,5,6,6a,7,8,9,10,10a-decahydro-3H-pyrido[1,2-a]quinolin-3-one; steroidal and non-steroidal 5alpha-reductase inhibitors as they inhibit the conversion of testosterone to 5alpha-dihydrotestosterone, detailed overview. Inhibitors with 4-methyl-4-aza functionality are very potent for type I enzyme. Potent inhibitors of steroid 5alpha-reductase are found among the transition state analogues as molecules mimicking the transition state of the enzymatic processes exhibit a greater binding to the enzyme and hence produce greater inhibition. The enzyme 5alpha-reductase binds the 3-keto-DELTA4 steroids in such a way that the carbonyl group is brought into vicinity of a positively charged centre on the enzyme whereby the conjugated ketone becomes activated. Poor inhibition by (4aS,6aS,7S,11aS)-7-hydroxy-4a,6a-dimethylhexadecahydro-2H-indeno[4,5-h]isoquinolin-2-one, (4aS,6aS,7S,11aS)-4a,6a-dimethylhexadecahydro-1H-indeno[4,5-h]isoquinolin-7-ol, (4aS,6aS,7S,11aR)-7-hydroxy-4a,6a-dimethyl-1,2,4,4a,5,6,6a,7,8,9,9a,10,11,11a-tetradecahydro-3H-indeno[5,4-f]isoquinolin-3-one, and (4aS,6aS,7S,11aR)-4a,6a-dimethyl-2,3,4,4a,5,6,6a,7,8,9,9a,10,11,11a-tetradecahydro-1H-indeno[5,4-f]isoquinolin-7-ol. No inhibition by (17E)-17-(hydroxyimino)androst-5-en-3-ol, (20Z)-20-(hydroxyimino)pregn-5-en-3-ol, (20Z)-20-(hydroxyimino)pregna-5,16-dien-3-ol, 20-(hydroxyimino)pregna-5,14-dien-3-ol, and 20-(hydroxyimino)pregna-5,14,16-trien-3-ol | Homo sapiens | |
| N,N-dicyclohexyl-4-(1-methyl-6-oxo-1,6-dihydropyridin-3-yl)benzamide | - |
Homo sapiens | |
| N,N-dicyclohexyl-4-(1-methyl-6-oxo-1,6-dihydropyridin-3-yl)benzamide | - |
Rattus norvegicus | |
| N-(1,1,1,3,3,3-hexafluorophenylpropyl)-3-oxo-4-aza-5-androst-1-ene-17-carboxamide | i.e. PNU 157706; i.e. PNU 157706 | Homo sapiens | |
| N-(3,3-dimethylbutyl)-N-[(4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]formamide | - |
Homo sapiens | |
| N-(3-methylbutan-2-yl)-N-[(4aR,6aS,7S,11aR)-1,4a,6a,10-tetramethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]formamide | - |
Homo sapiens | |
| N-(3-methylbutyl)-N-[(4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]formamide | - |
Homo sapiens | |
| N-(4-methoxycyclohexyl)-2-methyl-N-[(4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]propanamide | - |
Homo sapiens | |
| N-(dicyclohexyl)acetyl-piperidine-4-(benzylidene-4-carboxylic acid) | - |
Homo sapiens | |
| N-butyl-N-[(4aR,6aS,7S,11aR)-1,4a,6a,10-tetramethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]formamide | - |
Homo sapiens | |
| N-cyclohexyl-N-iodo-4-(2-methoxyquinolin-6-yl)benzamide | - |
Homo sapiens | |
| N-heptyl-N-[(4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]formamide | - |
Homo sapiens | |
| N-iodo-4-(2-methoxyquinolin-6-yl)benzamide | - |
Homo sapiens | |
| N-octyl-N-[(4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]formamide | - |
Homo sapiens | |
| N-pentyl-N-[(4aR,6aS,7S,11aR)-1,4a,6a,10-tetramethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]formamide | - |
Homo sapiens | |
| N-pentyl-N-[(4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]butanamide | - |
Homo sapiens | |
| N-pentyl-N-[(4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]formamide | - |
Homo sapiens | |
| N-phenyl-N-[(4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]benzamide | - |
Homo sapiens | |
| N-propyl-N-[(4aR,6aS,7S,11aR)-1,4a,6a,10-tetramethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]formamide | - |
Homo sapiens | |
| N-propyl-N-[(4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]formamide | - |
Homo sapiens | |
| N-tert-butyl-3-oxoestra-4,9(11)-diene-17-carboxamide | - |
Homo sapiens | |
| N-[1,1,1-trifluoro-2-oxobut-3-yl]-3-oxo-4-aza-5-androst-1-ene-17-carboxamide | - |
Homo sapiens | |
| N-[1,1,1-trifluoro-2-oxobut-3-yl]-3-oxo-4-aza-5-androst-1-ene-17-carboxamide | - |
Rattus norvegicus | |
| pregna-4,16-diene-3,6,20-trione | - |
Homo sapiens | |
| tricyclo[3.3.1.13,7]dec-2-yl (1S,9aR,11aS)-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxylate | - |
Homo sapiens | |
| [(17beta)-17-(propan-2-ylcarbamoyl)androsta-3,5-dien-3-yl]phosphinic acid | - |
Homo sapiens | |
| [(17beta)-17-(propan-2-ylcarbamoyl)androsta-3,5-dien-3-yl]phosphonic acid | - |
Homo sapiens | |
| [3-methyl-4-(4-phenoxybenzoyl)phenyl]acetic acid | - |
Homo sapiens | |
| [4-(4-phenoxybenzoyl)phenyl]acetic acid | - |
Homo sapiens | |
| [4-(biphenyl-4-yloxy)phenyl]acetic acid | - |
Homo sapiens | |
| [4-(biphenyl-4-yloxy)phenyl]acetic acid | - |
Rattus norvegicus | |
| [4-[4-(4-bromophenoxy)benzoyl]phenyl]acetic acid | - |
Homo sapiens | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| membrane | - |
Rattus norvegicus | 16020 | - |
| membrane | the enzyme is a system of two membrane bound NADPH-dependent enzymes at the level of prostatic stromal and basal cells | Homo sapiens | 16020 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 5alpha-dihydrotestosterone + NADP+ | Homo sapiens | the enzyme performs conversion of testosterone to 5alpha-dihydrotestosterone | testosterone + NADPH + H+ | - |
r | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | P18405 | gene SRD5A1; gene SRD5A1 | - |
| Homo sapiens | P31213 | gene SRD5A2; gene SRD5A2 | - |
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| dermal papilla cell | - |
Homo sapiens | - |
| epididymis | - |
Homo sapiens | - |
| fibroblast | from all areas | Homo sapiens | - |
| keratinocyte | epidermal and follicular | Homo sapiens | - |
| prostate | - |
Rattus norvegicus | - |
| prostate | the enzyme is a system of two membrane bound NADPH-dependent enzymes at the level of prostatic stromal and basal cells | Homo sapiens | - |
| seminal vesicle | - |
Homo sapiens | - |
| skin | genital | Homo sapiens | - |
| skin | sebaceous glands | Homo sapiens | - |
| sweat gland | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 5alpha-dihydrotestosterone + NADP+ | - |
Homo sapiens | testosterone + NADPH + H+ | - |
r | |
| 5alpha-dihydrotestosterone + NADP+ | the enzyme performs conversion of testosterone to 5alpha-dihydrotestosterone | Homo sapiens | testosterone + NADPH + H+ | - |
r | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| 3-oxo-steroid-4-ene dehydrogenase | - |
Rattus norvegicus |
| 3-oxo-steroid-4-ene dehydrogenase | - |
Homo sapiens |
| 5alpha-reductase | - |
Rattus norvegicus |
| 5alpha-reductase | - |
Homo sapiens |
| type I 5alpha-reductase | - |
Homo sapiens |
| type II 5alpha-reductase | - |
Homo sapiens |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NADP+ | - |
Homo sapiens | |
| NADPH | - |
Homo sapiens | |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.00001 | - |
(17beta)-4-fluoro-17-(propan-2-ylcarbamoyl)estra-1(10),2,4-triene-3-carboxylic acid | pH not specified in the publication, temperature not specified in the publication | Homo sapiens | |
| 0.00002 | - |
(17beta)-17-(propan-2-ylcarbamoyl)estra-1(10),2,4-triene-3-carboxylic acid | pH not specified in the publication, temperature not specified in the publication | Homo sapiens | |
| 0.000026 | - |
7-bromo-9,10-dihydrophenanthrene-2-carboxylic acid | pH not specified in the publication, temperature not specified in the publication | Homo sapiens | |
| 0.00003 | - |
(17beta)-17-(propan-2-ylcarbamoyl)estra-1(10),2,4,6-tetraene-3-carboxylic acid | pH not specified in the publication, temperature not specified in the publication | Homo sapiens | |
| 0.000031 | - |
(6aS,7S)-N,N-diethyl-6a-methyl-5,6,6a,7,8,9,9a,9b-octahydro-4bH-indeno[5,4-f]isoquinoline-7-carboxamide 2-oxide | pH not specified in the publication, temperature not specified in the publication | Homo sapiens | |
| 0.000035 | - |
(17beta)-2-chloro-17-(propan-2-ylcarbamoyl)estra-1(10),2,4-triene-3-carboxylic acid | pH not specified in the publication, temperature not specified in the publication | Homo sapiens | |
| 0.000036 | - |
(17beta)-17-(propan-2-ylcarbamoyl)estra-1(10),2,4,6,8-pentaene-3-carboxylic acid | pH not specified in the publication, temperature not specified in the publication | Homo sapiens | |
| 0.00009 | - |
6-[3-(N,N-dicyclohexylaminocarbonyl)phenyl]-3,4-dihydro-naphthalene-2-carboxylic acid | pH not specified in the publication, temperature not specified in the publication | Homo sapiens | |
| 0.00009 | - |
6-[4-(N,N-diisopropylamino-carbonyl)phenyl]naphthalene-2-carboxylic acid | pH not specified in the publication, temperature not specified in the publication | Homo sapiens | |
| 0.000104 | - |
(6aS,7S)-6a-methyl-N-(propan-2-yl)-5,6,6a,7,8,9,9a,9b-octahydro-4bH-indeno[5,4-f]isoquinoline-7-carboxamide 2-oxide | pH not specified in the publication, temperature not specified in the publication | Homo sapiens | |
| 0.00026 | - |
7-chloro-3,4,4a,9-tetrahydrophenanthrene-2-carboxylic acid | pH not specified in the publication, temperature not specified in the publication | Homo sapiens | |
| 0.000315 | - |
9,10-dihydrophenanthrene-2-carboxylic acid | pH not specified in the publication, temperature not specified in the publication | Homo sapiens | |
| 0.00032 | - |
7-chloro-9,10-dihydrophenanthrene-2-carboxylic acid | pH not specified in the publication, temperature not specified in the publication | Homo sapiens | |
| 0.00051 | - |
6-[4-(N,N-diisopropylcarbamoyl) phenyl]-N-methyl-quinolin-2-one | pH not specified in the publication, temperature not specified in the publication | Homo sapiens | |
| 0.0008 | - |
6-[4-(N,N-diisopropylcarbamoyl) phenyl]-1H-quinolin-2-one | pH not specified in the publication, temperature not specified in the publication | Homo sapiens | |
| 0.00092 | - |
(10bR)-8-chloro-5,10b-dimethyl-1,5,6,10b-tetrahydrophenanthridin-3(2H)-one | pH not specified in the publication, temperature not specified in the publication | Homo sapiens | |
| 0.00098 | - |
(4R)-5,10-seco-19-nor-pregna-4,5-diene-3,10,20-trione | pH not specified in the publication, temperature not specified in the publication | Homo sapiens | |
| 0.0011 | - |
(10bR)-8-chloro-4,5,10b-trimethyl-1,5,6,10b-tetrahydrophenanthridin-3(2H)-one | pH not specified in the publication, temperature not specified in the publication | Homo sapiens | |
| 0.0012 | - |
7-chloro-3,4,4a,9-tetrahydrophenanthrene-2-carboxylic acid | pH not specified in the publication, temperature not specified in the publication | Homo sapiens | |
| 0.0014 | - |
16-ethyl-17beta-hydroxy-4-estren-3-one | pH not specified in the publication, temperature not specified in the publication | Rattus norvegicus | |
| 0.0016 | - |
(7-chloro-3,4,4a,9-tetrahydrophenanthren-2-yl)phosphinic acid | pH not specified in the publication, temperature not specified in the publication | Homo sapiens | |
| 0.0019 | - |
(7-chloro-3,4,4a,9-tetrahydrophenanthren-2-yl)phosphinic acid | pH not specified in the publication, temperature not specified in the publication | Homo sapiens | |
| 0.0025 | - |
7-chloro-9,10-dihydrophenanthrene-2-carboxylic acid | pH not specified in the publication, temperature not specified in the publication | Homo sapiens | |
| 0.00547 | - |
(4R)-5,10-seco-estra-4,5-diene-3,10,17-trione | pH not specified in the publication, temperature not specified in the publication | Homo sapiens | |
| 0.01 | - |
9,10-dihydrophenanthrene-2-carboxylic acid | pH not specified in the publication, temperature not specified in the publication | Homo sapiens | |
| 0.01 | - |
7-bromo-9,10-dihydrophenanthrene-2-carboxylic acid | pH not specified in the publication, temperature not specified in the publication | Homo sapiens | |
| 0.01 | - |
(10bR)-8-chloro-4,10b-dimethyl-1,5,6,10b-tetrahydrophenanthridin-3(2H)-one | pH not specified in the publication, temperature not specified in the publication | Homo sapiens | |
IC50 Value
| IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
|---|---|---|---|---|---|
| 0.0000001 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aS,7S,11aR)-N-(diphenylmethyl)-4a,6a-dimethyl-2,5-dioxohexadecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.0000001 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aS,6aS,7S,11aS)-N,N-di(1H-indol-1-yl)-4a,6a-dimethyl-2-oxo-2,3,4,4a,5,6,6a,7,8,9,9a,10,11,11a-tetradecahydro-1H-indeno[4,5-h]isoquinoline-7-carboxamide | |
| 0.0000001 | - |
below, pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aS,7S,11aR)-N-(diphenylmethyl)-4a,6a-dimethyl-2,5-dioxohexadecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.0000001 | - |
below, pH not specified in the publication, temperature not specified in the publication | Homo sapiens | tricyclo[3.3.1.13,7]dec-2-yl (1S,9aR,11aS)-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxylate | |
| 0.0000001 | - |
below, pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1S,9aR,11aS)-N-[2-tert-butyl-5-(trifluoromethyl)phenyl]-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | |
| 0.0000001 | - |
below, pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aS,6aS,7S,11aS)-4a,6a-dimethyl-2-oxo-N-[2-(trifluoromethyl)phenyl]-2,3,4,4a,5,6,6a,7,8,9,9a,10,11,11a-tetradecahydro-1H-indeno[4,5-h]isoquinoline-7-carboxamide | |
| 0.0000001 | - |
below, pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1S,9aR,11aS)-9a,11a-dimethyl-N-(2-methylpropyl)-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | |
| 0.0000001 | - |
below, pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1S,9aR,11aS)-6-bromo-9a,11a-dimethyl-7-oxo-N-(tricyclo[3.3.1.13,7]dec-1-yl)-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | |
| 0.0000001 | - |
below, pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1S,9aR,11aS)-N-(diphenylmethyl)-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | |
| 0.0000001 | - |
below, pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1S,9aR,11aS)-N-(diphenylmethyl)-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | |
| 0.0000001 | - |
below, pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1S,9aR,11aR)-1-butyl-9a,11a-dimethyl-1,2,3,3a,3b,4,5,8,9,9a,9b,10,11,11a-tetradecahydro-7H-cyclopenta[i]phenanthridin-7-one | |
| 0.0000001 | - |
below, pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1S,9aR,11aS)-9a,11a-dimethyl-1-nonanoyl-1,2,3,3a,3b,4,5,8,9,9a,9b,10,11,11a-tetradecahydro-7H-cyclopenta[i]phenanthridin-7-one | |
| 0.0000001 | - |
below, pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1S,9aR,11aS)-1-(cyclohexylacetyl)-9a,11a-dimethyl-1,2,3,3a,3b,4,5,8,9,9a,9b,10,11,11a-tetradecahydro-7H-cyclopenta[i]phenanthridin-7-one | |
| 0.0000001 | - |
below, pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1S,9aR,11aS)-N-(5-bromo-2-tert-butylphenyl)-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | |
| 0.0000001 | - |
below, pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1S,9aR,11aS)-N-(4-tert-butylbiphenyl-3-yl)-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | |
| 0.0000001 | - |
below, pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1S,9aR,11aS)-N-(4,4'-di-tert-butylbiphenyl-3-yl)-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | |
| 0.0000001 | - |
below, pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1S,9aR,11aS)-N-[2,5-bis(trifluoromethyl)phenyl]-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | |
| 0.0000001 | - |
below, pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1S,9aR,11aS)-N-[1-(4-chlorophenyl)cyclobutyl]-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | |
| 0.0000001 | - |
below, pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1S,9aR,11aS)-6-chloro-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | |
| 0.00000012 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1S,9aR,11aS)-N-[bis(4-chlorophenyl)methyl]-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | |
| 0.00000016 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | tricyclo[3.3.1.13,7]dec-2-yl (1S,9aR,11aS)-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxylate | |
| 0.0000002 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aS,7S)-4a,6a-dimethyl-2,5-dioxo-N-phenyl-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.0000002 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (11aR)-7-(1-hydroxypropan-2-yl)-1,4a,6a-trimethyltetradecahydrocyclopenta[5,6]naphtho[2,1-d][1,3]oxazine-2(1H)-thione | |
| 0.0000002 | - |
below, pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aS,6aS,7S,11aS)-N-(biphenyl-3-yl)-4a,6a-dimethyl-2-oxo-2,3,4,4a,5,6,6a,7,8,9,9a,10,11,11a-tetradecahydro-1H-indeno[4,5-h]isoquinoline-7-carboxamide | |
| 0.0000004 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aS,6aS,7S,11aS)-4a,6a-dimethyl-2-oxo-N,N-diphenyl-2,3,4,4a,5,6,6a,7,8,9,9a,10,11,11a-tetradecahydro-1H-indeno[4,5-h]isoquinoline-7-carboxamide | |
| 0.0000004 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1S,9aR,11aS)-N-(dicyclohexylmethyl)-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | |
| 0.0000005 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aS,7S,11aR)-N-[2,5-bis(trifluoromethyl)phenyl]-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.0000005 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 1-cyclopropyl-3-methyl-1-[(4aR,6aS,7S,11aR)-1,4a,6a,10-tetramethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]urea | |
| 0.00000052 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (17beta)-16-ethyl-17-hydroxyandrost-4-en-3-one | |
| 0.00000055 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,5S,6aS,11aR)-N-(diphenylmethyl)-5-hydroxy-4a,6a,10-trimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.00000056 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 4-(biphenyl-4-yloxy)-3-methoxybenzoic acid | |
| 0.0000006 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 5-(2-ethyl-3-[3-[(4-hexylundecyl)amino]benzoyl]-1H-pyrrol-1-yl)pentanoate | |
| 0.0000006 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aR)-1,4a,6a,10-tetramethyl-7-(6-methylheptan-2-yl)-1,3,4,4a,4b,5,6,6a,7,8,9,9a,9b,10-tetradecahydro-2H-indeno[5,4-f]quinolin-2-one | |
| 0.0000006 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1S,9aR,11aS)-6-chloro-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | |
| 0.00000062 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (16alpha,17beta)-17-hydroxy-16-methylandrost-4-en-3-one | |
| 0.00000067 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 4-(biphenyl-4-yloxy)-2-fluorobenzoic acid | |
| 0.0000007 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1R,4R,9aR,11aR)-4,9a,11a-trimethyl-1-((R)-6-methylheptan-2-yl)-3,3a,3b,4,5,8,9,9a,9b,10,11,11a-dodecahydro-1H-cyclopenta[i]phenanthridin-7(2H)-one | |
| 0.00000087 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 4-(biphenyl-4-yloxy)-2-chlorobenzoic acid | |
| 0.0000009 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aS,7S,11aR)-4a,6a-dimethyl-2-oxo-N-(4,4,4-trifluoro-3-oxobutan-2-yl)-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.00000091 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | N-pentyl-N-[(4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]formamide | |
| 0.000001 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aS,7S,11aR)-N-(diphenylmethyl)-1,4a,6a-trimethyl-2,5-dioxohexadecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.000001 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1R,4S,9aR,11aR)-4,9a,11a-trimethyl-1-((R)-6-methylheptan-2-yl)-3,3a,3b,4,5,8,9,9a,9b,10,11,11a-dodecahydro-1H-cyclopenta[i]phenanthridin-7(2H)-one | |
| 0.000001 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1R,9aR,11aR)-9a,11a-dimethyl-1-((R)-6-methylheptan-2-yl)-3,3a,3b,4,5,8,9,9a,9b,10,11,11a-dodecahydro-1H-cyclopenta[i]phenanthridin-7(2H)-one | |
| 0.000001 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1S,9aR,11aS)-9a,11a-dimethyl-1-nonanoyl-1,2,3,3a,3b,4,5,8,9,9a,9b,10,11,11a-tetradecahydro-7H-cyclopenta[i]phenanthridin-7-one | |
| 0.0000012 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1R,4S,9aR,11aR)-4,9a,11a-trimethyl-1-((R)-6-methylheptan-2-yl)-3,3a,3b,4,5,8,9,9a,9b,10,11,11a-dodecahydro-1H-cyclopenta[i]phenanthridin-7(2H)-one | |
| 0.0000013 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 1-cyclopropyl-3-phenyl-1-[(4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]urea | |
| 0.0000013 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1S,9aR,11aS)-N-(4,4'-di-tert-butylbiphenyl-3-yl)-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | |
| 0.0000014 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1S,9aR,11aS)-N-tert-butyl-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | |
| 0.0000015 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1S,9aR,11aS)-N,N-diethyl-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | |
| 0.0000016 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aS,7S,11aR)-N-(diphenylmethyl)-4a,6a-dimethyl-2,5-dioxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.0000016 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aR)-4a,6a,10-trimethyl-7-(6-methylheptan-2-yl)-1,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-2H-indeno[5,4-f]quinolin-2-one | |
| 0.0000017 | - |
pH not specified in the publication, temperature not specified in the publication | Rattus norvegicus | (S)-4-[1-[4-[[1-(4-isobutylphenyl)butyl]oxy]benzoyl]indolizin-3-yl]butyric acid | |
| 0.0000017 | - |
pH not specified in the publication, temperature not specified in the publication | Rattus norvegicus | (S)-4-[1-[4-[[1-(4-isobutylphenyl)butyl]oxy]benzoyl]indolizin-3-yl]-butyric acid | |
| 0.0000017 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 17beta-N,N-diethylcarbamoyl-4-methyl-4-aza-5alpha-androstan-3-one | |
| 0.0000017 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (5alpha17beta)-17-N,N-diethylcarbamoyl-4-methyl-4-aza-5-androstan-3-one | |
| 0.0000017 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aR)-1,4a,6a-trimethyl-7-(6-methylheptan-2-yl)hexadecahydro-2H-indeno[5,4-f]quinolin-2-one | |
| 0.00000177 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | N-pentyl-N-[(4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]butanamide | |
| 0.0000018 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | N-pentyl-N-[(4aR,6aS,7S,11aR)-1,4a,6a,10-tetramethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]formamide | |
| 0.0000018 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | N-(1,1,1,3,3,3-hexafluorophenylpropyl)-3-oxo-4-aza-5-androst-1-ene-17-carboxamide | |
| 0.0000018 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1S,9aS,11aS)-N,N-diethyl-8,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,7,9a,9b,10,11,11a-dodecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | |
| 0.0000018 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (3beta)-6,20-dioxopregna-4,16-dien-3-yl 3-bromopropanoate | |
| 0.0000019 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 17beta-N,N-diethylcarbamoyl-4-methyl-4-aza-5alpha-androstan-3-one | |
| 0.0000019 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 4-[3-[3-[bis(4-isobutylphenyl)methylamino]benzoyl]-lH-indol-l-yl]butyric acid | |
| 0.0000019 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aS,6aS,7S,11aR)-4a,6a-dimethyl-2,3,4,4a,5,6,6a,7,8,9,9a,10,11,11a-tetradecahydro-1H-indeno[5,4-f]isoquinolin-7-ol | |
| 0.0000019 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 4-[3-[3-[bis (4-isobutylphenyl)methyl amino] benzoyl]-lH-indol-l-yl] butyric acid | |
| 0.000002 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aR)-1,4a,6a,10-tetramethyl-7-(6-methylheptan-2-yl)-1,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-2H-indeno[5,4-f]quinolin-2-one | |
| 0.000002 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aS,7S)-1,4a,6a-trimethyl-2,5-dioxo-N-[2-(trifluoromethyl)phenyl]-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.0000021 | - |
pH not specified in the publication, temperature not specified in the publication | Rattus norvegicus | 4-[(1-benzyl-1H-indol-5-yl)oxy]-3-chlorobenzoic acid | |
| 0.0000021 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 4-[(1-benzyl-1H-indol-5-yl)oxy]-3-chlorobenzoic acid | |
| 0.0000021 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1S,9aR,11aS)-6-bromo-N,N-diethyl-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | |
| 0.00000219 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | N-(3-methylbutyl)-N-[(4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]formamide | |
| 0.0000022 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | N-(3-methylbutan-2-yl)-N-[(4aR,6aS,7S,11aR)-1,4a,6a,10-tetramethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]formamide | |
| 0.0000023 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1R,9aR,11aR)-9a,11a-dimethyl-1-((R)-6-methylheptan-2-yl)-3,3a,3b,4,5,8,9,9a,9b,10,11,11a-dodecahydro-1H-cyclopenta[i]phenanthridin-7(2H)-one | |
| 0.0000023 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 1-cyclopropyl-3-phenyl-1-[(4aR,6aS,7S,11aR)-1,4a,6a,10-tetramethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]urea | |
| 0.0000023 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1S,9aR,11aS)-N,N-diethyl-5,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | |
| 0.00000235 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | N-(3,3-dimethylbutyl)-N-[(4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]formamide | |
| 0.0000024 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 17beta-N-(2,5-bis(trifluoromethyl)-phenyl)-3-oxo-4-aza-5alpha-androst-1-ene-17-carboxamide | |
| 0.00000242 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 5-bromo-N-pentyl-N-[(4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]pentanamide | |
| 0.0000026 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | N-butyl-N-[(4aR,6aS,7S,11aR)-1,4a,6a,10-tetramethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]formamide | |
| 0.0000029 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,5S,6aS,11aR)-N-(diphenylmethyl)-5-hydroxy-1,4a,6a,10-tetramethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.0000029 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (17beta)-N-tert-butyl-4-cyano-3-oxoandrost-4-ene-17-carboxamide | |
| 0.00000293 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | N-phenyl-N-[(4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]benzamide | |
| 0.000003 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (5alpha17beta)-17-N,N-diethylcarbamoyl-4-methyl-4-aza-5-androstan-3-one | |
| 0.000003 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 6,20-dioxopregna-4,16-dien-3-yl 4-fluorobenzoate | |
| 0.000003 | - |
type II 5alpha-reductase, pH not specified in the publication, temperature not specified in the publication | Homo sapiens | finasteride | |
| 0.00000305 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | N-propyl-N-[(4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]formamide | |
| 0.0000032 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 3-cyclohexyl-1-cyclopropyl-1-[(4aR,6aS,7S,11aR)-1,4a,6a,10-tetramethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]urea | |
| 0.0000032 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | methyl (1S,9aR,11aS)-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxylate | |
| 0.0000033 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (22R,S)-N-(1,1,1-trifluoro-2-phenylprop-2-yl)-3-oxo-4-aza-5-androst-1-ene-17-carboxamide | |
| 0.0000034 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1S,8bS,10aS)-N,N-diethyl-8b,10a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,7,7a,8,8a,8b,8c,9,10,10a-hexadecahydrocyclopenta[i]cyclopropa[a]phenanthridine-1-carboxamide | |
| 0.0000035 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1S,8bS,10aS)-N,N-diethyl-8b,10a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,7,7a,8,8a,8b,8c,9,10,10a-hexadecahydrocyclopenta[i]cyclopropa[a]phenanthridine-1-carboxamide | |
| 0.0000036 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1S,9aR,11aS)-N-(diphenylmethyl)-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | |
| 0.0000036 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (5aR,9aR,11aS)-1-(3,3-dimethylbutanoyl)-6,9a,11a-trimethylhexadecahydro-7H-indolo[5,4-f]quinolin-7-one | |
| 0.0000037 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 6,20-dioxopregn-4-en-3-yl 4-fluorobenzoate | |
| 0.0000038 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | N-phenyl-N-[(4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]benzamide | |
| 0.0000039 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | N-(1,1,1,3,3,3-hexafluorophenylpropyl)-3-oxo-4-aza-5-androst-1-ene-17-carboxamide | |
| 0.0000039 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1S,9aR,11aS)-N,N-diethyl-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | |
| 0.000004 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1S,9aR,11aS)-1-(cyclohexylacetyl)-9a,11a-dimethyl-1,2,3,3a,3b,4,5,8,9,9a,9b,10,11,11a-tetradecahydro-7H-cyclopenta[i]phenanthridin-7-one | |
| 0.000004 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1S,9aR,11aS)-N-[2,5-bis(trifluoromethyl)phenyl]-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | |
| 0.000004 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 6,20-dioxopregna-4,16-dien-3-yl 4-methylbenzoate | |
| 0.000004 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 4-[3-(4-[(1R)-1-[4-(2-methylpropyl)phenyl]ethoxy]benzoyl)-1H-indol-1-yl]butanoic acid | |
| 0.0000042 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1S,9aR,11aS)-N-(5-bromo-2-tert-butylphenyl)-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | |
| 0.0000042 | - |
pH not specified in the publication, temperature not specified in the publication | Rattus norvegicus | 4-[3-[3-[bis(4-isobutylphenyl)methylamino]benzoyl]-lH-indol-l-yl]butyric acid | |
| 0.0000045 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1S,9aR,11aS)-6-bromo-9a,11a-dimethyl-7-oxo-N-(tricyclo[3.3.1.13,7]dec-1-yl)-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | |
| 0.0000046 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (S)-4-[1-[4-[[1-(4-isobutylphenyl)butyl]oxy]benzoyl]indolizin-3-yl]butyric acid | |
| 0.0000046 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (S)-4-[1-[4-[[1-(4-isobutylphenyl)butyl]oxy]benzoyl]indolizin-3-yl]-butyric acid | |
| 0.0000046 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1S,9aR,11aS)-N-(4-tert-butylbiphenyl-3-yl)-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | |
| 0.0000048 | - |
pH not specified in the publication, temperature not specified in the publication | Rattus norvegicus | (17beta)-16-ethyl-17-hydroxyandrost-4-en-3-one | |
| 0.000005 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (2R,3R,10aR,12aS)-2,10a,12a-trimethyl-1,8-dioxo-3-phenyl-1,2,3,4,4a,4b,8,9,10,10a,10b,11,12,12a-tetradecahydrochrysen-2-yl (2-fluorophenyl)acetate | |
| 0.000005 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | [3-methyl-4-(4-phenoxybenzoyl)phenyl]acetic acid | |
| 0.000005 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aS,7S)-1,4a,6a-trimethyl-2,5-dioxo-N-phenylhexadecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.000005 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 4-(4-benzoylphenoxy)benzoic acid | |
| 0.000005 | - |
pH not specified in the publication, temperature not specified in the publication | Rattus norvegicus | 4-[1-(6,6-dimethyl-6H-dibenzo[b,d]pyran-3-yl)methylindol-3-yl]-butyric acid | |
| 0.0000051 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | N-propyl-N-[(4aR,6aS,7S,11aR)-1,4a,6a,10-tetramethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]formamide | |
| 0.0000053 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 3-chloro-4-([1-(4-phenoxybenzyl)indolin-5-yl]oxy)benzoic acid | |
| 0.0000053 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 3-butyl-1-cyclopropyl-1-[(4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]urea | |
| 0.0000054 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aR)-1,4a,6a-trimethyl-7-(6-methylheptan-2-yl)-10-propyl-1,3,4,4a,4b,5,6,6a,7,8,9,9a,9b,11a-tetradecahydro-2H-indeno[5,4-f]quinolin-2-one | |
| 0.00000544 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | N-(4-methoxycyclohexyl)-2-methyl-N-[(4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]propanamide | |
| 0.0000055 | - |
pH not specified in the publication, temperature not specified in the publication | Rattus norvegicus | 3-chloro-4-(4-[N-(4-phenoxybenzyl)amino] phenoxy)benzoic acid | |
| 0.0000056 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aS,6aS,7S,11aS)-4a,6a-dimethyl-2-oxo-N-[2-(trifluoromethyl)phenyl]-2,3,4,4a,5,6,6a,7,8,9,9a,10,11,11a-tetradecahydro-1H-indeno[4,5-h]isoquinoline-7-carboxamide | |
| 0.0000057 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aR)-10-ethyl-1,4a,6a-trimethyl-7-(6-methylheptan-2-yl)hexadecahydro-2H-indeno[5,4-f]quinolin-2-one | |
| 0.0000057 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1S,9aR,11aS)-N,N-diethyl-5,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,7,9a,9b,10,11,11a-dodecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | |
| 0.0000058 | - |
pH not specified in the publication, temperature not specified in the publication | Rattus norvegicus | 5-(2-ethyl-3-[3-[(4-hexylundecyl)amino]benzoyl]-1H-pyrrol-1-yl)pentanoate | |
| 0.000006 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aS,7S)-N-(2-chlorophenyl)-1,4a,6a-trimethyl-2,5-dioxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.000006 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aS,7S)-N-[2,5-bis(trifluoromethyl)phenyl]-1,4a,6a-trimethyl-2,5-dioxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.000006 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,10bR)-4,10b-dimethyl-8-[(E)-2-phenylethenyl]-1,4,4a,5,6,10b-hexahydrobenzo[f]quinolin-3(2H)-one | |
| 0.000006 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,10bR)-8-[(E)-2-(isoquinolin-4-yl)ethenyl]-4,10b-dimethyl-1,4,4a,5,6,10b-hexahydrobenzo[f]quinolin-3(2H)-one | |
| 0.000006 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4-[[1-(dicyclohexylacetyl)piperidin-4-ylidene]methyl]phenyl)acetic acid | |
| 0.0000068 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1S,9aR,11aS)-N-[1-(4-chlorophenyl)cyclobutyl]-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | |
| 0.0000069 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | tricyclo[3.3.1.13,7]dec-2-yl (1S,9aR,11aS)-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxylate | |
| 0.000007 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aS,7S)-1,4a,6a-trimethyl-2,5-dioxo-N-[2-(trifluoromethyl)phenyl]-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.000007 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (17beta)-17-[di(propan-2-yl)carbamoyl]androsta-3,5-diene-3-carboxylic acid | |
| 0.000007 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (17beta)-17-[di(propan-2-yl)carbamoyl]androsta-2,4,6-triene-3-carboxylic acid | |
| 0.000007 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (17beta)-17-[di(propan-2-yl)carbamoyl]androsta-3,5,11-triene-3-carboxylic acid | |
| 0.000007 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4-[[1-(dicyclohexylacetyl)piperidin-4-ylidene]methyl]-3-fluorophenyl)acetic acid | |
| 0.0000076 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 8-chloro-4-methyl-4,4a,5,6-tetrahydro-3H-pyrido[1,2-a]quinolin-3-one | |
| 0.0000079 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1R,4R,9aR,11aR)-4,9a,11a-trimethyl-1-((R)-6-methylheptan-2-yl)-3,3a,3b,4,5,8,9,9a,9b,10,11,11a-dodecahydro-1H-cyclopenta[i]phenanthridin-7(2H)-one | |
| 0.000008 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aS,11aR)-1,4a,6a,10-tetramethyl-N-(2-methyl-4-oxopentan-3-yl)-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.000008 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,10bR)-8-chloro-4-methyl-1,4,4a,5,6,10b-hexahydrobenzo[f]quinolin-3(2H)-one | |
| 0.0000081 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aS,7S,11aR)-N-[2,5-bis(trifluoromethyl)phenyl]-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.0000084 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aR)-1,4a,6a-trimethyl-7-(6-methylheptan-2-yl)-10-propyl-1,3,4,4a,4b,5,6,6a,7,8,9,9a,9b,11a-tetradecahydro-2H-indeno[5,4-f]quinolin-2-one | |
| 0.0000085 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 8-chloro-4,6-dimethyl-4,4a,5,6-tetrahydro-3H-pyrido[1,2-a]quinolin-3-one | |
| 0.0000088 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1S,9aR,11aS)-N-[2-tert-butyl-5-(trifluoromethyl)phenyl]-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | |
| 0.000009 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1S,9aR,11aS)-6-chloro-N,N-diethyl-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | |
| 0.000009 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1S,9aR,11aS)-9a,11a-dimethyl-N-(2-methylpropyl)-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | |
| 0.00000957 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | N-heptyl-N-[(4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]formamide | |
| 0.0000096 | - |
pH not specified in the publication, temperature not specified in the publication | Rattus norvegicus | 4-(2-[1-(4,4'-dipropylbenzhydryl)indole-5-carboxamido]phenoxy)butyric acid | |
| 0.0000098 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 4'-[2-[di(propan-2-yl)amino]-2-oxoethoxy]-3'-fluoro-5'-nitrobiphenyl-4-carboxylic acid | |
| 0.00001 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aS,7S)-N-(2-chlorophenyl)-1,4a,6a-trimethyl-2,5-dioxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.00001 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (3beta)-6,20-dioxopregna-4,16-dien-3-yl 3-iodopropanoate | |
| 0.00001 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,10bR)-8-(furan-2-yl)-4,10b-dimethyl-1,4,4a,5,6,10b-hexahydrobenzo[f]quinolin-3(2H)-one | |
| 0.00001 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 4-[4-(4-methylbenzoyl)phenoxy]benzoic acid | |
| 0.00001 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 4-(3-[[2,2-bis(4-chlorophenyl)-1,3-benzodioxol-5-yl]carbonyl]-2-methyl-1H-indol-1-yl)butanoic acid | |
| 0.00001 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 3-chloro-4-(4-[N-(4-phenoxybenzyl)amino]phenoxy)benzoic acid | |
| 0.0000103 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (5aR,9aR,11aS)-1-(3,3-dimethylbutanoyl)-9a,11a-dimethyl-1,2,3,3a,3b,4,5,5a,6,9a,9b,10,11,11a-tetradecahydro-7H-indolo[5,4-f]quinolin-7-one | |
| 0.0000105 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 2-methyl-N-phenyl-N-[(4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]propanamide | |
| 0.000011 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aS,7S)-1,4a,6a-trimethyl-2,5-dioxo-N-phenylhexadecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.000011 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,10bR)-4,8-dimethyl-1,4,4a,5,6,10b-hexahydrobenzo[f]quinolin-3(2H)-one | |
| 0.000011 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 4-[[1-(dicyclohexylacetyl)piperidin-4-ylidene]methyl]-3-fluorobenzoic acid | |
| 0.0000115 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 1-cyclopropyl-3-phenyl-1-[(4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]urea | |
| 0.000012 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1S,9aR,11aS)-N-tert-butyl-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | |
| 0.000012 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1S,9aR,11aR)-1-butyl-9a,11a-dimethyl-1,2,3,3a,3b,4,5,8,9,9a,9b,10,11,11a-tetradecahydro-7H-cyclopenta[i]phenanthridin-7-one | |
| 0.000013 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aS,7S)-4a,6a-dimethyl-2,5-dioxo-N-phenyl-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.000013 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1S,9aR,11aS)-N,N-diethyl-5,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,7,9a,9b,10,11,11a-dodecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | |
| 0.000013 | - |
pH not specified in the publication, temperature not specified in the publication | Rattus norvegicus | ethyl 4-[2-[([1-[bis(4-propylphenyl)methyl]-1H-benzimidazol-5-yl]carbonyl)amino]phenoxy]butanoate | |
| 0.000014 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aS,6aS,7S,11aS)-N-(biphenyl-3-yl)-4a,6a-dimethyl-2-oxo-2,3,4,4a,5,6,6a,7,8,9,9a,10,11,11a-tetradecahydro-1H-indeno[4,5-h]isoquinoline-7-carboxamide | |
| 0.000014 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | N-heptyl-N-[(4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]formamide | |
| 0.000014 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aS,11aR)-1,4a,6a,10-tetramethyl-2-oxo-N-(4,4,4-trifluoro-2-methyl-3-oxobutan-2-yl)-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.000014 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1S,9aS,11aS)-N,N-diethyl-8,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,7,9a,9b,10,11,11a-dodecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | |
| 0.000014 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (3beta)-6,20-dioxopregna-4,16-dien-3-yl 3-chloropropanoate | |
| 0.0000143 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 6,8-dimethyl-1,2,5,6-tetrahydro-3H-pyrido[1,2-a]quinolin-3-one | |
| 0.000015 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aS,7S)-4a,6a-dimethyl-2,5-dioxo-N-phenylhexadecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.000016 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aS,11aR)-1,4a,6a,10-tetramethyl-2-oxo-N-(4,4,4-trifluoro-3-oxobutan-2-yl)-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.0000169 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | N-octyl-N-[(4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]formamide | |
| 0.000017 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,10bR)-8-chloro-4,10b-dimethyl-1,4,4a,5,6,10b-hexahydrobenzo[f]quinolin-3(2H)-one | |
| 0.0000184 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | N-octyl-N-[(4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]formamide | |
| 0.00002 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | tricyclo[3.3.1.13,7]dec-2-yl (1S,9aR,11aS)-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxylate | |
| 0.00002 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 4,8-dimethyl-1,2,5,6-tetrahydro-3H-pyrido[1,2-a]quinolin-3-one | |
| 0.00002 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aS,6aS,7S,11aS)-4a,6a-dimethyl-2-oxo-N-phenyl-2,3,4,4a,5,6,6a,7,8,9,9a,10,11,11a-tetradecahydro-1H-indeno[4,5-h]isoquinoline-7-carboxamide | |
| 0.00002 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aS,7S)-N,4a,6a-trimethyl-2,5-dioxo-N-phenyl-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.00002 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aS,7S)-N-[2,5-bis(trifluoromethyl)phenyl]-1,4a,6a-trimethyl-2,5-dioxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.00002 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1S,9aR,11aS)-N-[bis(4-chlorophenyl)methyl]-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | |
| 0.00002 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1S,9aR,11aS)-N-(dicyclohexylmethyl)-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | |
| 0.000023 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | [4-(4-phenoxybenzoyl)phenyl]acetic acid | |
| 0.000023 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 4-[3-([(2R)-2-methyl-2-[4-(2-methylpropyl)phenyl]-1,3-benzodioxol-5-yl]carbonyl)-1H-indol-1-yl]butanoic acid | |
| 0.0000235 | - |
pH not specified in the publication, temperature not specified in the publication | Rattus norvegicus | (16alpha,17beta)-17-hydroxy-16-methylandrost-4-en-3-one | |
| 0.0000242 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 3-butyl-1-cyclopropyl-1-[(4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinolin-7-yl]urea | |
| 0.0000246 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aS,6aS,7S,11aS)-4a,6a-dimethyl-2-oxo-N-phenyl-2,3,4,4a,5,6,6a,7,8,9,9a,10,11,11a-tetradecahydro-1H-indeno[4,5-h]isoquinoline-7-carboxamide | |
| 0.000025 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 4-[3-([(2R)-2-methyl-2-[4-(2-methylpropyl)phenyl]-1,3-benzodioxol-5-yl]carbonyl)-1H-indol-1-yl]butanoic acid | |
| 0.0000252 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aS,6aS,7S,11aS)-4a,6a-dimethyl-7-[methyl(phenyl)carbamoyl]-2-oxo-2,3,4,4a,5,6,6a,7,8,9,9a,10,11,11a-tetradecahydro-1H-indeno[4,5-h]isoquinolinium | |
| 0.000026 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (17beta)-17-[di(propan-2-yl)carbamoyl]-4-fluoroandrost-3-ene-3-carboxylic acid | |
| 0.000027 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | [4-[4-(4-bromophenoxy)benzoyl]phenyl]acetic acid | |
| 0.0000273 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 1-cyclopropyl-3-ethyl-1-[(4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]urea | |
| 0.00003 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | epristeride | |
| 0.00003 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aS,7S)-1,4a,6a-trimethyl-2,5-dioxo-N-phenyl-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.00003 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1S,9aR,11aS)-N-(diphenylmethyl)-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | |
| 0.00003 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (17beta)-17-[di(propan-2-yl)carbamoyl]androst-3-ene-3-carboxylic acid | |
| 0.00003 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 8-chloro-4-methyl-1,4,5,6-tetrahydrobenzo[f]quinolin-3(2H)-one | |
| 0.0000315 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 3-cyclohexyl-1-cyclopropyl-1-[(4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]urea | |
| 0.000032 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (17beta)-17-[di(propan-2-yl)carbamoyl]-6-fluoroandrosta-3,5-diene-3-carboxylic acid | |
| 0.000033 | - |
pH not specified in the publication, temperature not specified in the publication | Rattus norvegicus | (4aR,6aS,7S,11aR)-N-(diphenylmethyl)-1,4a,6a-trimethyl-2,5-dioxohexadecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.000033 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 6-bromo-3,20-dioxopregna-4,6-dien-17-yl acetate | |
| 0.000035 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (17beta)-17-[di(propan-2-yl)carbamoyl]-4-methylandrosta-3,5-diene-3-carboxylic acid | |
| 0.000035 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,10bR)-8-fluoro-4-methyl-1,4,4a,5,6,10b-hexahydrobenzo[f]quinolin-3(2H)-one | |
| 0.000035 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,10bR)-8-bromo-4-methyl-1,4,4a,5,6,10b-hexahydrobenzo[f]quinolin-3(2H)-one | |
| 0.000036 | - |
pH not specified in the publication, temperature not specified in the publication | Rattus norvegicus | (4aR,6aS,11aR)-N-(2-cyanopropan-2-yl)-1,4a,6a,10-tetramethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.000036 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (22R,S)-N-(1,1,1-trifluoro-2-phenylprop-2-yl)-3-oxo-4-aza-5-androst-1-ene-17-carboxamide | |
| 0.0000379 | - |
pH not specified in the publication, temperature not specified in the publication | Rattus norvegicus | 4-[2-(6-[[bis(4-fluorophenyl)methyl]carbamoyl]-1-benzofuran-2-yl)phenoxy]butanoic acid | |
| 0.000039 | - |
pH not specified in the publication, temperature not specified in the publication | Rattus norvegicus | (4aR,6aS,7S,11aR)-N-(diphenylmethyl)-4a,6a-dimethyl-2,5-dioxohexadecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.00004 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1S,9aR,11aS)-N,N-diethyl-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | |
| 0.00004 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 4-[3-(4-[(1R)-1-[4-(2-methylpropyl)phenyl]ethoxy]benzoyl)-1H-indol-1-yl]butanoic acid | |
| 0.0000401 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (5aR,9aR,11aS)-1-(3,3-dimethylbutanoyl)-9a,11a-dimethylhexadecahydro-7H-indolo[5,4-f]quinolin-7-one | |
| 0.000041 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aS,7S,11aR)-N-cyclohexyl-N-(cyclohexylacetyl)-1,4a,6a-trimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.000041 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 17beta-N-(2,5-bis(trifluoromethyl)-phenyl)-3-oxo-4-aza-5alpha-androst-1-ene-17-carboxamide | |
| 0.000045 | - |
pH not specified in the publication, temperature not specified in the publication | Rattus norvegicus | 4-cyanoprogesterone | |
| 0.000046 | - |
pH not specified in the publication, temperature not specified in the publication | Rattus norvegicus | 3-chloro-4-([1-(4-phenoxybenzyl)indolin-5-yl]oxy)benzoic acid | |
| 0.000049 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 8-chloro-1,2,5,6-tetrahydro-3H-pyrido[1,2-a]quinolin-3-one | |
| 0.00005 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 4-[2-(6-[[bis(4-fluorophenyl)methyl]carbamoyl]-1-benzofuran-2-yl)phenoxy]butanoic acid | |
| 0.00005 | - |
pH not specified in the publication, temperature not specified in the publication | Rattus norvegicus | (4aR,5S,6aS,11aR)-N-(diphenylmethyl)-5-hydroxy-4a,6a,10-trimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.00005 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 4-cyanoprogesterone | |
| 0.00005 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aS,7S)-N,1,4a,6a-tetramethyl-2,5-dioxo-N-phenyl-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.00005 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (17beta)-17-[di(propan-2-yl)carbamoyl]estra-3,5-diene-3-carboxylic acid | |
| 0.000051 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | N-[1,1,1-trifluoro-2-oxobut-3-yl]-3-oxo-4-aza-5-androst-1-ene-17-carboxamide | |
| 0.000051 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1S,9aR,11aS)-6-chloro-N,N-diethyl-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | |
| 0.000052 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (9aR,11aS)-1-(3,3-dimethylbutanoyl)-6,9a,11a-trimethyl-1,2,3,3a,3b,4,6,8,9,9a,9b,10,11,11a-tetradecahydro-7H-indolo[5,4-f]quinolin-7-one | |
| 0.000053 | - |
pH not specified in the publication, temperature not specified in the publication | Rattus norvegicus | (4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-N-(3-methylbutanoyl)-2-oxo-N-(propan-2-yl)hexadecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.000055 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-N-(3-methylbutanoyl)-2-oxo-N-(propan-2-yl)hexadecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.000055 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aS,7S,11aR)-N-(3,3-dimethylpentanoyl)-1,4a,6a-trimethyl-N-(2-methylbutan-2-yl)-2-oxohexadecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.000058 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 8-chloro-1,2,5,6,7,8,9,10-octahydro-3H-pyrido[1,2-a]quinolin-3-one | |
| 0.000059 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,10bR)-8-(furan-2-yl)-4,10b-dimethyl-1,4,4a,5,6,10b-hexahydrobenzo[f]quinolin-3(2H)-one | |
| 0.00006 | - |
pH not specified in the publication, temperature not specified in the publication | Rattus norvegicus | N-[1,1,1-trifluoro-2-oxobut-3-yl]-3-oxo-4-aza-5-androst-1-ene-17-carboxamide | |
| 0.00006 | - |
pH not specified in the publication, temperature not specified in the publication | Rattus norvegicus | 4-[[1-(dicyclohexylacetyl)piperidin-4-ylidene]methyl]benzoic acid | |
| 0.00006 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | [4-(biphenyl-4-yloxy)phenyl]acetic acid | |
| 0.00006 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 8-bromo-4-methyl-1,4,5,6-tetrahydrobenzo[f]quinolin-3(2H)-one | |
| 0.00006 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,10bR)-8-chloro-1,4,4a,5,6,10b-hexahydrobenzo[f]quinolin-3(2H)-one | |
| 0.000067 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 4-(1-benzyl-1H-indol-5-yl)benzoic acid | |
| 0.000071 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 4'-[2-[di(propan-2-yl)amino]-2-oxoethoxy]-3',5'-di(propan-2-yl)biphenyl-4-carboxylic acid | |
| 0.000073 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 3-chloro-4-([1-(4-phenoxybenzoyl)-1H-indol-5-yl]oxy)benzoic acid | |
| 0.000073 | - |
pH not specified in the publication, temperature not specified in the publication | Rattus norvegicus | 3-chloro-4-[(1-(4-phenoxybenzoyl)-1H-indol-5-yl]oxy)benzoic acid | |
| 0.000074 | - |
pH not specified in the publication, temperature not specified in the publication | Rattus norvegicus | (4aR,6aS,7S,11aR)-N-(diphenylmethyl)-4a,6a-dimethyl-2,5-dioxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.000074 | - |
pH not specified in the publication, temperature not specified in the publication | Rattus norvegicus | (4aR,5S,6aS,11aR)-N-(diphenylmethyl)-5-hydroxy-1,4a,6a,10-tetramethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.00008 | - |
pH not specified in the publication, temperature not specified in the publication | Rattus norvegicus | 4-[[1-(dicyclohexylacetyl)piperidin-4-ylidene]methyl]benzoic acid | |
| 0.000083 | - |
pH not specified in the publication, temperature not specified in the publication | Rattus norvegicus | (4aR,6aS,7S,11aR)-N-cyclohexyl-N-(cyclohexylacetyl)-1,4a,6a-trimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.000097 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1S,9aR,11aS)-6-bromo-N,N-diethyl-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | |
| 0.0001 | - |
above, pH not specified in the publication, temperature not specified in the publication | Homo sapiens | N-propyl-N-[(4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]formamide | |
| 0.0001 | - |
above, pH not specified in the publication, temperature not specified in the publication | Homo sapiens | N-pentyl-N-[(4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]formamide | |
| 0.0001 | - |
above, pH not specified in the publication, temperature not specified in the publication | Homo sapiens | N-(3-methylbutyl)-N-[(4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]formamide | |
| 0.0001 | - |
above, pH not specified in the publication, temperature not specified in the publication | Homo sapiens | N-(3,3-dimethylbutyl)-N-[(4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]formamide | |
| 0.000107 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 1-methyl-5-[4-[(E)-2-phenylethenyl]phenyl]piperidin-2-one | |
| 0.00012 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aS,6aS,7S,11aS)-N,N-di(1H-indol-1-yl)-4a,6a-dimethyl-2-oxo-2,3,4,4a,5,6,6a,7,8,9,9a,10,11,11a-tetradecahydro-1H-indeno[4,5-h]isoquinoline-7-carboxamide | |
| 0.00012 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aS,7S)-N,1,4a,6a-tetramethyl-2,5-dioxo-N-phenyl-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.000125 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aR)-1,4a,6a,10-tetramethyl-7-(6-methylheptan-2-yl)-1,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-2H-indeno[5,4-f]quinolin-2-one | |
| 0.000137 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 4,8-dimethyl-1,2,5,6-tetrahydro-3H-pyrido[1,2-a]quinolin-3-one | |
| 0.000147 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aR)-1,4a,6a,10-tetramethyl-7-(6-methylheptan-2-yl)-1,3,4,4a,4b,5,6,6a,7,8,9,9a,9b,10-tetradecahydro-2H-indeno[5,4-f]quinolin-2-one | |
| 0.00015 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | methyl(1S,9aR,11aS)-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxylate | |
| 0.000152 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 7-[(E)-2-phenylethenyl]-9,10-dihydrophenanthrene-2-carboxylic acid | |
| 0.000154 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aS,7S,11aR)-4a,6a-dimethyl-2-oxo-N-(4,4,4-trifluoro-3-oxobutan-2-yl)-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.000174 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (5aR,9aR,11aS)-1-(3,3-dimethylbutanoyl)-6,9a,11a-trimethyl-1,2,3,3a,3b,4,5,5a,6,9a,9b,10,11,11a-tetradecahydro-7H-indolo[5,4-f]quinolin-7-one | |
| 0.000176 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 8-methyl-1,2,5,6-tetrahydro-3H-pyrido[1,2-a]quinolin-3-one | |
| 0.00018 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1S,9aR,11aS)-N,N-diethyl-5,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | |
| 0.000183 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,10bR)-8-chloro-4,10b-dimethyl-1,4,4a,5,6,10b-hexahydrobenzo[f]quinoline-3(2H)-thione | |
| 0.000192 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (17beta)-N-tert-butyl-4-chloro-3-oxoandrost-4-ene-17-carboxamide | |
| 0.0002 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 6-[4-(N,N-diisopropylamino-carbonyl)phenyl]naphthalene-2-carboxylic acid | |
| 0.000204 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 8-chloro-1-methyl-1,2,5,6-tetrahydro-3H-pyrido[1,2-a]quinolin-3-one | |
| 0.00021 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aS,7S)-1,4a,6a-trimethyl-2,5-dioxo-N-phenyl-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.000212 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aS,7S,11aR)-N-cyclohexyl-N-(cyclohexylacetyl)-1,4a,6a-trimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.000212 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aS,7S,11aR)-N-(3,3-dimethylpentanoyl)-1,4a,6a-trimethyl-N-(2-methylbutan-2-yl)-2-oxohexadecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.000218 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aR)-1,4a,6a-trimethyl-7-(6-methylheptan-2-yl)hexadecahydro-2H-indeno[5,4-f]quinolin-2-one | |
| 0.000227 | - |
pH not specified in the publication, temperature not specified in the publication | Rattus norvegicus | (4aR,6aS,7S,11aR)-4a,6a-dimethyl-N-(3-methylbutanoyl)-2-oxo-N-(propan-2-yl)hexadecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.000247 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (7aS,8S,12aR)-8-[benzyl(phenyl)amino]-7a-methyl-5a,6,7,7a,8,9,10,10a,10b,11,12,12a-dodecahydrocyclopenta[f]pyrido[1,2-a]quinolin-2(1H)-one | |
| 0.000262 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aS,11aR)-N-(2-cyanopropan-2-yl)-1,4a,6a,10-tetramethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.000279 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (7aS,8S,12aR)-7a-methyl-8-(phenylamino)-5a,6,7,7a,8,9,10,10a,10b,11,12,12a-dodecahydrocyclopenta[f]pyrido[1,2-a]quinolin-2(1H)-one | |
| 0.00029 | - |
pH not specified in the publication, temperature not specified in the publication | Rattus norvegicus | 4-[[1-(2-propylpentanoyl)piperidin-4-ylidene]methyl]benzoic acid | |
| 0.000298 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aR)-4a,6a,10-trimethyl-7-(6-methylheptan-2-yl)-1,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-2H-indeno[5,4-f]quinolin-2-one | |
| 0.0003 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (21E)-21-(hydroxyimino)pregn-4-en-3-one | |
| 0.0003 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 17beta-(N-tert-butylcarbamoyl)-4-aza-5alpha-androst-1-en-3-one | |
| 0.0003 | - |
type I 5alpha-reductase, pH not specified in the publication, temperature not specified in the publication | Homo sapiens | finasteride | |
| 0.000302 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 1-methyl-5-[4-[(E)-phenyldiazenyl]phenyl]piperidin-2-one | |
| 0.000318 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (7aR,9aS,10S)-N,N-diethyl-7a,9a-dimethyl-5-oxo-1,2,3,5,6,7,7a,7b,8,9,9a,10,11,12,12a,12b-hexadecahydrobenzo[b]indeno[5,4-d]azepine-10-carboxamide | |
| 0.00033 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aR)-10-ethyl-1,4a,6a-trimethyl-7-(6-methylheptan-2-yl)hexadecahydro-2H-indeno[5,4-f]quinolin-2-one | |
| 0.00034 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 4-[2-(6-[[bis(4-fluorophenyl)methyl]carbamoyl]-1-benzofuran-2-yl)phenoxy]butanoic acid | |
| 0.00034 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 7-[(E)-2-phenylethenyl]-9,10-dihydrophenanthrene-2-carboxylic acid | |
| 0.00035 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aS,6aS,7S,11aS)-4a,6a-dimethyl-7-[methyl(phenyl)carbamoyl]-2-oxo-2,3,4,4a,5,6,6a,7,8,9,9a,10,11,11a-tetradecahydro-1H-indeno[4,5-h]isoquinolinium | |
| 0.00037 | - |
pH not specified in the publication, temperature not specified in the publication | Rattus norvegicus | 4-[[1-(diphenylacetyl)piperidin-4-ylidene]methyl]benzoic acid | |
| 0.000377 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (10bR)-8-chloro-4,10b-dimethyl-1,4,6,10b-tetrahydrobenzo[f]quinoline-3(2H)-thione | |
| 0.00038 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 4-[4-(tricyclo[3.3.1.13,7]dec-2-ylcarbamoyl)phenoxy]benzoic acid | |
| 0.000381 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-N-(3-methylbutanoyl)-2-oxo-N-(propan-2-yl)hexadecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.000381 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aS,7S,11aR)-4a,6a-dimethyl-N-(3-methylbutanoyl)-2-oxo-N-(propan-2-yl)hexadecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.000387 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (17beta)-4-bromo-N-tert-butyl-3-oxoandrost-4-ene-17-carboxamide | |
| 0.00041 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aS,7S)-4a,6a-dimethyl-2,5-dioxo-N-phenylhexadecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.00042 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aS,7S)-N,4a,6a-trimethyl-2,5-dioxo-N-phenyl-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.000437 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (17beta)-N-tert-butyl-3-oxo-4-sulfanylandrost-4-ene-17-carboxamide | |
| 0.000459 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 8-chloro-4,4a,5,6-tetrahydro-3H-pyrido[1,2-a]quinolin-3-one | |
| 0.00046 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (8a,9b,10x,14x)-N-tert-butyl-3-oxoestr-4-ene-17-carboxamide | |
| 0.00046 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 8-chloro-1,4,5,6-tetrahydrobenzo[f]quinolin-3(2H)-one | |
| 0.000477 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (5aR,9aR,11aS)-1-(3,3-dimethylbutanoyl)-6,9a,11a-trimethyl-1,2,3,3a,3b,4,5,5a,6,9a,9b,10,11,11a-tetradecahydro-7H-indolo[5,4-f]quinolin-7-one | |
| 0.00049 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 2-oxo-8-(prop-2-en-1-yl)-2H-chromen-7-yl benzoate | |
| 0.00054 | - |
pH not specified in the publication, temperature not specified in the publication | Rattus norvegicus | 4-[[1-(biphenyl-4-ylcarbamoyl)piperidin-4-ylidene]methyl]benzoic acid | |
| 0.000579 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 1-methyl-5-[4-[(E)-phenyldiazenyl]phenyl]piperidin-2-one | |
| 0.00058 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (20E)-20-(hydroxyimino)pregn-4-en-3-one | |
| 0.000582 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 2-methyl-N-phenyl-N-[(4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]propanamide | |
| 0.000617 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 1-methyl-5-[4-[(E)-2-phenylethenyl]phenyl]piperidin-2-one | |
| 0.00068 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 6-[4-[di(propan-2-yl)carbamoyl]phenyl]-3,4-dihydronaphthalene-2-carboxylic acid | |
| 0.00069 | - |
pH not specified in the publication, temperature not specified in the publication | Rattus norvegicus | 4-[[1-(biphenyl-4-ylcarbamoyl)piperidin-4-ylidene]methyl]benzoic acid | |
| 0.000709 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (17beta)-N-tert-butyl-3-oxo-4-sulfanylandrost-4-ene-17-carboxamide | |
| 0.00075 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 6-[3-(N,N-dicyclohexylaminocarbonyl)phenyl]-3,4-dihydro-naphthalene-2-carboxylic acid | |
| 0.00075 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (1S,9aR,11aS)-N,N-diethyl-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | |
| 0.000765 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (5aR,9aR,11aS)-1-(3,3-dimethylbutanoyl)-9a,11a-dimethyl-1,2,3,3a,3b,4,5,5a,6,9a,9b,10,11,11a-tetradecahydro-7H-indolo[5,4-f]quinolin-7-one | |
| 0.00081 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 6-[3-(N,N-dicyclohexylaminocarbonyl)phenyl]-3,4-dihydro-naphthalene-2-carboxylic acid | |
| 0.00084 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 4-(3-(4-(N-methylacetamido)phenyl) pentan-3-yl) phenyldibenzylcarbamate | |
| 0.000913 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (7aS,8S,12aR)-8-[benzyl(phenyl)amino]-7a-methyl-5a,6,7,7a,8,9,10,10a,10b,11,12,12a-dodecahydrocyclopenta[f]pyrido[1,2-a]quinolin-2(1H)-one | |
| 0.000981 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (17beta)-4-bromo-N-tert-butyl-3-oxoandrost-4-ene-17-carboxamide | |
| 0.00099 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 8-allyl-7-hydroxycoumarin | |
| 0.001 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aS,6aS,7S,11aS)-4a,6a-dimethyl-2-oxo-N,N-diphenyl-2,3,4,4a,5,6,6a,7,8,9,9a,10,11,11a-tetradecahydro-1H-indeno[4,5-h]isoquinoline-7-carboxamide | |
| 0.001 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (17beta)-N-tert-butyl-4-chloro-3-oxoandrost-4-ene-17-carboxamide | |
| 0.001 | - |
about, pH not specified in the publication, temperature not specified in the publication | Homo sapiens | N-pentyl-N-[(4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]butanamide | |
| 0.001 | - |
about, pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 5-bromo-N-pentyl-N-[(4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]pentanamide | |
| 0.001 | - |
about, pH not specified in the publication, temperature not specified in the publication | Homo sapiens | N-(4-methoxycyclohexyl)-2-methyl-N-[(4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinolin-7-yl]propanamide | |
| 0.001134 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (8a,9b,10x,14x)-N-tert-butyl-3-oxoestr-4-ene-17-carboxamide | |
| 0.001218 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aS,7S,11aR)-4a,6a-dimethyl-N-(3-methylbutanoyl)-2-oxo-N-(propan-2-yl)hexadecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.001218 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-N-(3-methylbutanoyl)-2-oxo-N-(propan-2-yl)-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.0013 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,10bR)-8-[(E)-2-(isoquinolin-4-yl)ethenyl]-4,10b-dimethyl-1,4,4a,5,6,10b-hexahydrobenzo[f]quinolin-3(2H)-one | |
| 0.0013 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 7-[(3-methylbut-2-en-1-yl)oxy]-2H-chromen-2-one | |
| 0.0014 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,10bR)-4,10b-dimethyl-8-[(E)-2-phenylethenyl]-1,4,4a,5,6,10b-hexahydrobenzo[f]quinolin-3(2H)-one | |
| 0.001553 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-N-(3-methylbutanoyl)-2-oxo-N-(propan-2-yl)-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.001553 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,6aS,7S,11aR)-4a,6a-dimethyl-N-(3-methylbutanoyl)-2-oxo-N-(propan-2-yl)-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.001554 | - |
pH not specified in the publication, temperature not specified in the publication | Rattus norvegicus | (4aR,6aS,7S,11aR)-4a,6a-dimethyl-N-(3-methylbutanoyl)-2-oxo-N-(propan-2-yl)-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.001611 | - |
pH not specified in the publication, temperature not specified in the publication | Rattus norvegicus | (4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-N-(3-methylbutanoyl)-2-oxo-N-(propan-2-yl)-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide | |
| 0.00163 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (20E)-20-(hydroxyimino)pregn-4-en-3-one | |
| 0.00169 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 5-(4-chlorophenyl)-1-methylpiperidin-2-one | |
| 0.00195 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (21E)-21-(hydroxyimino)pregn-4-en-3-one | |
| 0.002 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (7aS,8S,12aR)-7a-methyl-8-(phenylamino)-5a,6,7,7a,8,9,10,10a,10b,11,12,12a-dodecahydrocyclopenta[f]pyrido[1,2-a]quinolin-2(1H)-one | |
| 0.0022 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (5aR,9aR,11aS)-1-(3,3-dimethylbutanoyl)-9a,11a-dimethylhexadecahydro-7H-indolo[5,4-f]quinolin-7-one | |
| 0.002477 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 1-methyl-5-phenylpiperidin-2-one | |
| 0.00336 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 5-(4-chlorophenyl)-1-methylpiperidine-2-thione | |
| 0.00344 | - |
pH not specified in the publication, temperature not specified in the publication | Rattus norvegicus | 4-[[1-(diphenylacetyl)piperidin-4-ylidene]methyl]benzoic acid | |
| 0.004 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (6aS,8S,10aS,12aS)-8-hydroxy-1,10a,12a-trimethylhexadecahydronaphtho[2,1-f]quinolin-2(1H)-one | |
| 0.0046 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | estra-4,9(11)-diene-3,17-dione | |
| 0.00513 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 4,4a,5,6,7,8,9,10-octahydro-3H-pyrido[1,2-a]quinolin-3-one | |
| 0.0063 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 4-(3-[[2,2-bis(4-chlorophenyl)-1,3-benzodioxol-5-yl]carbonyl]-2-methyl-1H-indol-1-yl)butanoic acid | |
| 0.0065 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 1,4,5,6-tetrahydrobenzo[f]quinolin-3(2H)-one | |
| 0.007 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (9aR,11aS)-1-(3,3-dimethylbutanoyl)-6,9a,11a-trimethyl-1,2,3,3a,3b,4,6,8,9,9a,9b,10,11,11a-tetradecahydro-7H-indolo[5,4-f]quinolin-7-one | |
| 0.01 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (4aR,10bR)-8-chloro-4-methyl-1,4,4a,5,6,10b-hexahydrobenzo[f]quinolin-3(2H)-one | |
| 0.012 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (6aR,7S,9aR,11aS)-7-hydroxy-1,9a,11a-trimethylhexadecahydro-2H-indeno[5,4-f]quinolin-2-one | |
| 0.0123 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 5-(4-chlorophenyl)-1-methylpiperidin-2-one | |
| 0.015 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (6aS,10aS,12aS)-1,10a,12a-trimethylhexadecahydronaphtho[2,1-f]quinoline-2,8-dione | |
| 0.02 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 8-chloro-1,2,5,6,6a,7,8,9,10,10a-decahydro-3H-pyrido[1,2-a]quinolin-3-one | |
| 0.04 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (8R,9aS,11aS)-1,9a,11a-trimethyl-2-oxo-N,N-di(propan-2-yl)hexadecahydro-1H-indeno[5,4-f]quinoline-8-carboxamide | |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | a third type of 5alpha-reductase enzyme type III occurs in hormone-refractory prostate cancer cells | Homo sapiens |
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Release 2023.1 (January 2023)
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