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BRENDA support

Literature summary for 1.3.99.6 extracted from

  • Sheenan, P.M.; Rice, G.E.; Moses, E.K.; Brennecke, S.P.
    5beta-Dihydroprogesterone and steroid 5beta-reductase decrease in association with human parturition at term (2005), Mol. Hum. Reprod., 11, 495-501.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
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Source Tissue

Source Tissue Comment Organism Textmining
amnion lowest expression Homo sapiens
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blood from patients late in pregnancy, before term labour, during term labour and within the first 24 h postpartum Homo sapiens
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chorion
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Homo sapiens
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myometrium relative expression decreases significantly in association with labour by about 10fold Homo sapiens
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placenta most highly expressed, relative expression decreases significantly in association with labour by about 2fold Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
progesterone + NADPH + H+
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Homo sapiens 5beta-pregnane-3,20-dione + NADP+
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?

Synonyms

Synonyms Comment Organism
steroid 5beta-reductase
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Homo sapiens