Protein Variants | Comment | Organism |
---|---|---|
additional information | construction of a deletion mutant by targeted mutagenesis, the mutant mice lacking the enzyme activity dies soon after parturition exhibiting cardivascular instability with ruptured arterial aneurysms and diaphragmatic rupture due to fragmented elastic fiber architecture in the aorta, overview, the homozygous mutants show about 60% reduced activity in lung and aorta compared to the wild-type mice | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Mus musculus | enzyme is responsible for the cross-linking of collagen and elastin, and is required for vascular and diaphragmatic development during embryogenesis | ? | - |
? | |
peptidyl-L-lysyl-peptide + O2 + H2O | Mus musculus | - |
peptidyl-allysyl-peptide + NH3 + H2O2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | enzyme is responsible for the cross-linking of collagen and elastin, and is required for vascular and diaphragmatic development during embryogenesis | Mus musculus | ? | - |
? | |
peptidyl-L-lysyl-peptide + O2 + H2O | - |
Mus musculus | peptidyl-allysyl-peptide + NH3 + H2O2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
LOX | - |
Mus musculus |
lysyl oxidase | - |
Mus musculus |