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Literature summary for 1.4.3.13 extracted from
- Repression of BCL2 by the tumor suppressor activity of the lysyl oxidase propeptide inhibits transformed phenotype of lung and pancreatic cancer cells (2007), Cancer Res., 67, 6278-6285.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in NCI-H1299, NIH-3T3 and PANC-1 cells | Mus musculus |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 32000 | - |
mature LOX, SDS-PAGE | Mus musculus |
| 50000 | - |
precursor Pro-LOX, SDS-PAGE | Mus musculus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| lung cancer cell | LOX gene expression is reduced in lung cancer cells | Mus musculus | - |
| pancreatic cancer cell | LOX gene expression is reduced in pancreatic cancer cells | Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| peptidyl-L-lysyl-peptide + O2 + H2O | - |
Mus musculus | peptidyl-allysyl-peptide + NH3 + H2O2 | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| LOX | - |
Mus musculus |
| lysyl oxidase | - |
Mus musculus |
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Release 2023.1 (January 2023)
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