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Literature summary for 1.4.3.13 extracted from

  • Contente, S.; Yeh, T.J.; Friedman, R.M.
    Tumor suppressive effect of lysyl oxidase proenzyme (2009), Biochim. Biophys. Acta, 1793, 1272-1278.
    View publication on PubMed
Search for more literature for 1.4.3.13

Cloned(Commentary)

Cloned (Comment) Organism
expression of mature enzyme, proenzyme, and of isolated propeptide in Escherichia coli strain BL21-A1 Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm proenzyme Mus musculus 5737
-
extracellular mature enzyme Mus musculus
-
-
additional information the enzyme is secreted as inactive enzyme of about 50 kDa and processed to a mature about 30 kDa enzyme Mus musculus
-
-
nucleus proenzyme Mus musculus 5634
-

Organism

Organism UniProt Comment Textmining
Mus musculus
-
 Swiss mice and FVB/N mice
-

Posttranslational Modification

Posttranslational Modification Comment Organism
proteolytic modification the enzyme is secereted as inactive enzyme of about 50 kDa and processed into a mature about 30 kDa enzyme and a 18 kDa propeptide Mus musculus

Source Tissue

Source Tissue Comment Organism Textmining
fibroblast
-
 Mus musculus
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NIH-3T3 cell
-
 Mus musculus
-

Synonyms

Synonyms Comment Organism
LOX
-
 Mus musculus
lysyl oxidase
-
 Mus musculus

General Information

General Information Comment Organism
physiological function lysyl oxidase acts as both a matrix modifying enzyme and an oncogene suppressor Mus musculus