Inhibitors | Comment | Organism | Structure |
---|---|---|---|
beta-aminopropionitrile | - |
Danio rerio | |
Disulfiram | a dithiocarbamate and Cu2+-chelator, inhibits the enzyme and causes teratogenic effects, malformations, distorted notochord development, and shortened anterior to posterior axis in zebrafish, overview | Danio rerio | |
thiram | a dithiocarbamate and Cu2+-chelator, inhibits the enzyme and causes teratogenic effects, malformations, distorted notochord development, and shortened anterior to posterior axis in zebrafish, overview | Danio rerio |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Cu2+ | dependent on | Danio rerio |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Danio rerio | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
embryo | - |
Danio rerio | - |
Synonyms | Comment | Organism |
---|---|---|
LOX | - |
Danio rerio |
lysyl oxidase | - |
Danio rerio |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8.2 | - |
assay at | Danio rerio |
General Information | Comment | Organism |
---|---|---|
additional information | partial knockdown of three LOX genes, lox,loxl1 and loxl5b, sensitizes the developing embryo to dithiocarbamate exposure | Danio rerio |