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Literature summary for 1.4.3.13 extracted from

  • Smith, M.A.; Gonzalez, J.; Hussain, A.; Oldfield, R.N.; Johnston, K.A.; Lopez, K.M.
    Overexpression of soluble recombinant human lysyl oxidase by using solubility tags effects on activity and solubility (2016), Enzyme Res., 2016, 5098985 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
beta-aminopropionitrile complete inhibition at 0.5 mM Homo sapiens
phenylhydrazine
-
Homo sapiens

Metals/Ions

Metals/Ions Comment Organism Structure
Cu2+ dependent on Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
peptidyl-L-lysyl-peptide + O2 + H2O Homo sapiens
-
peptidyl-allysyl-peptide + NH3 + H2O2
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
Ni-NTA column chromatography Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1,5-diaminopentane + O2 + H2O
-
Homo sapiens ?
-
?
peptidyl-L-lysyl-peptide + O2 + H2O
-
Homo sapiens peptidyl-allysyl-peptide + NH3 + H2O2
-
?

Subunits

Subunits Comment Organism
? x * 29000, active mature enzyme, SDS-PAGE Homo sapiens
? x * 50000, pre-proenzyme, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
LOX
-
Homo sapiens
lysyl oxidase
-
Homo sapiens