Literature summary for 1.4.3.14 extracted from

Krupyanko, V.; Medentsev, A.; Lukasheva, E.; Arinbasarova, A.
Kinetic characteristics of L-lysine alpha-oxidase from Trichoderma cf. aureoviride Rifai VKM F-4268D Substrate specificity and allosteric effects (2017), Biochem. Biophys. Rep., 9, 9-12 .

No PubMed abstract available

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Inhibitors

Inhibitors	Comment	Organism	Structure
1,4-diaminobutane	-	Trichoderma aureoviride
6-aminocaproic acid	most effective inhibitor	Trichoderma aureoviride
alpha-keto-zeta-aminocaproic acid	-	Trichoderma aureoviride
L-2,7-diaminoheptanoic acid	-	Trichoderma aureoviride
L-alanine	-	Trichoderma aureoviride
L-leucine	-	Trichoderma aureoviride

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.01015	-	L-lysine	at pH 7.5 and 37°C	Trichoderma aureoviride

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
L-lysine + O2 + H2O	Trichoderma aureoviride	-	6-amino-2-oxohexanoate + NH3 + H2O2	-	?

Organism

Organism	UniProt	Comment	Textmining
Trichoderma aureoviride	-	Rifai VKM F-4268D	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2,6-diaminopimelate + O2 + H2O	22% activity compared to L-lysine	Trichoderma aureoviride	?	-	?
L-arginine + O2 + H2O	12.8% activity compared to L-lysine	Trichoderma aureoviride	5-guanidino-2-oxopentanoate + NH3 + H2O2	-	?
L-lysine + O2 + H2O	-	Trichoderma aureoviride	6-amino-2-oxohexanoate + NH3 + H2O2	-	?
L-ornithine + O2 + H2O	8.3% activity compared to L-lysine	Trichoderma aureoviride	5-amino-2-oxopentanoic acid + NH3 + H2O2	-	?
additional information	no activity with N-2-trifluoroacetyl-L-lysine, 6-aminocaproic acid, 1,4-diaminobutane, L-alanine, L-leucine, L-glutamic acid, L-2,7-diamino heptanoic acid, L-glutamine, and D-lysine	Trichoderma aureoviride	?	-	?

Synonyms

Synonyms	Comment	Organism
L-lysine alpha-oxidase	-	Trichoderma aureoviride
LysOx	-	Trichoderma aureoviride

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Release 2023.1 (January 2023)