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Literature summary for extracted from

  • Macho, A.; Boutrot, F.; Rathjen, J.; Zipfel, C.
    Aspartate oxidase plays an important role in Arabidopsis stomatal immunity (2012), Plant Physiol., 159, 1845-1856.
    View publication on PubMedView publication on EuropePMC


Localization Comment Organism GeneOntology No. Textmining
Arabidopsis thaliana 9507

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-aspartate + O2 Arabidopsis thaliana
alpha-iminosuccinate + H2O2


Organism UniProt Comment Textmining
Arabidopsis thaliana
ecotype Col-0

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-aspartate + O2
Arabidopsis thaliana alpha-iminosuccinate + H2O2


Synonyms Comment Organism
Arabidopsis thaliana


Cofactor Comment Organism Structure
Arabidopsis thaliana

General Information

General Information Comment Organism
malfunction although the enzyme mutation dramatically affects NADPH oxidase RBOHD function, it does not affect functions carried out by other members of the RBOH family, such as RBOHC and RBOHF Arabidopsis thaliana
metabolism the enzyme catalyzes the first irreversible step in the de novo biosynthesis of NAD+ Arabidopsis thaliana
additional information full enzyme activity is not required for flg22-induced responses that are NADPH oxidase RBOHD-independent Arabidopsis thaliana
physiological function the enzyme is required for the reactive oxygen species burst mediated by the NADPH oxidase RBOHD triggered by the perception of several unrelated pathogen-associated molecular patterns. The enzyme is also required for RBOHD-dependent stomatal closure. The enzyme is required for stomatal immunity against the bacterium Pseudomonas syringa Arabidopsis thaliana