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Literature summary for 1.4.3.21 extracted from

  • Bour, S.; Caspar-Bauguil, S.; Iffiu-Soltesz, Z.; Nibbelink, M.; Cousin, B.; Miiluniemi, M.; Salmi, M.; Stolen, C.; Jalkanen, S.; Casteilla, L.; Penicaud, L.; Valet, P.; Carpene, C.
    Semicarbazide-sensitive amine oxidase/vascular adhesion protein-1 deficiency reduces leukocyte infiltration into adipose tissue and favors fat deposition (2009), Am. J. Pathol., 174, 1075-1083.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.4.3.21

Protein Variants

Protein Variants Comment Organism
additional information construction of AOC3-KO mice which show white adipose tissue with lower CD45 mRNA levels and fewer CD45+ leukocytes and diminished infiltration by T cells, macrophages, natural killer, and natural killer T cells, the phenotype is not rescued by human SSAO/VAP-1 expression on adipocytes under the control of aP2, overview Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Mus musculus 16020
-

Organism

Organism UniProt Comment Textmining
Mus musculus
-
 female and male C57BL/6 mice, gene AOC3
-

Source Tissue

Source Tissue Comment Organism Textmining
adipocyte
-
 Mus musculus
-
endothelial cell
-
 Mus musculus
-
white adipose tissue
-
 Mus musculus
-

Synonyms

Synonyms Comment Organism
semicarbazide-sensitive amine oxidase
-
 Mus musculus
SSAO
-
 Mus musculus
SSAO/VAP-1
-
 Mus musculus
VAP-1
-
 Mus musculus
vascular adhesion protein-1
-
 Mus musculus

Expression

Organism Comment Expression
Mus musculus AOC3 knockout mice show white adipose tissue with lower CD45 mRNA levels and fewer CD45+ leukocytes and diminished infiltration by T cells, macrophages, natural killer, and natural killer T cells down

General Information

General Information Comment Organism
malfunction enzyme deficiency reduces leukocyte infiltration into adipose tissue and favors fat deposition Mus musculus
physiological function the enzyme is present on the endothelial cell surface where it is involved in leukocyte extravasation Mus musculus