Cloned (Comment) | Organism |
---|---|
AGAO is overexpressed recombinantly as a C-terminal Strep-tagII fusion protein | Arthrobacter globiformis |
Crystallization (Comment) | Organism |
---|---|
complexes of amine oxidase with the inhibitors benzylhydrazine and tranylcypromine are refined at 1.86 and 1.65 A resolution, respectively. Both inhibitors form covalent adducts with the 2,4,5-trihydroxyphenylalanine quinone cofactor. Tyrosine residue 296, proposed to act as a gate to the AGAO active site, is in its open conformation | Arthrobacter globiformis |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
benzylhydrazine | - |
Arthrobacter globiformis | |
tranylcypromine | - |
Arthrobacter globiformis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Arthrobacter globiformis | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
AGAO | - |
Arthrobacter globiformis |
Amine oxidase | - |
Arthrobacter globiformis |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
2,4,5-trihydroxyphenylalanine quinone | - |
Arthrobacter globiformis |