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Literature summary for 1.4.3.3 extracted from

  • Miyoshi, Y.; Hamase, K.; Tojo, Y.; Mita, M.; Konno, R.; Zaitsu, K.
    Determination of D-serine and D-alanine in the tissues and physiological fluids of mice with various D-amino-acid oxidase activities using two-dimensional high-performance liquid chromatography with fluorescence detection (2009), J. Chromatogr. B, 877, 2506-2512.
    View publication on PubMed
Search for more literature for 1.4.3.3

Protein Variants

Protein Variants Comment Organism
additional information comparison of D-Ser and D-Ala contents in different tissues in wild-type DAO+/+ mice with knockout mice DAO-/- and heterozygous DAO+/- mice, detailed overview Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus P18894
-
-

Source Tissue

Source Tissue Comment Organism Textmining
cerebellum
-
 Mus musculus
-
cerebral cortex
-
 Mus musculus
-
hippocampus
-
 Mus musculus
-
hypothalamus
-
 Mus musculus
-
kidney
-
 Mus musculus
-
liver
-
 Mus musculus
-
medulla oblongata
-
 Mus musculus
-
olfactory bulb
-
 Mus musculus
-
pancreas
-
 Mus musculus
-
pituitary gland
-
 Mus musculus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
 comparison of D-Ser and D-Ala contents in different tissues in wild-type DAO+/+ mice with knockout mice DAO-/- and heterozygous DAO+/- mice, detailed overview Mus musculus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-alanine + H2O + O2 the D-amino acid is a modulator of the N-methyl-D-aspartate receptor mediated neurotransmission Mus musculus pyruvate + NH3 + H2O2
-
 ?
D-serine + H2O + O2 the D-amino acid is a modulator of the N-methyl-D-aspartate receptor mediated neurotransmission Mus musculus 2-oxo-3-hydroxypropionate + NH3 + H2O2
-
 ?