Literature summary for 1.4.3.4 extracted from

Binda, C.; Hubalek, F.; Li, M.; Edmondson, D.E.; Mattevi, A.
Crystal structure of human monoamine oxidase B, a drug target enzyme monotopically inserted into the mitochondrial outer membrane (2004), FEBS Lett., 564, 225-228.

Search for more literature for 1.4.3.4

Application

Application	Comment	Organism
medicine	the enzyme is a valuable target for many neurological disorders	Homo sapiens

Crystallization (Commentary)

Crystallization (Comment)	Organism
-	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
mitochondrial membrane	outer, membrane may have a role in controlling substrate binding, C-terminal transmembrane helix protrudes from each monomer and anchors the protein to the membrane, several apolar loops exposed on the protein surface are located in proximity of the C-terminal helix, providing additional membrane-binding interactions	Homo sapiens	31966	-
mitochondrion	outer membrane	Homo sapiens	5739	-

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P27338	-	-

Subunits

Subunits	Comment	Organism
dimer	C-terminal transmembrane helix protruding from each monomer and anchoring the protein to the membrane	Homo sapiens

Synonyms

Synonyms	Comment	Organism
MAO B	-	Homo sapiens
monoamine oxidase B	-	Homo sapiens

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Release 2023.1 (January 2023)