Inhibitors | Comment | Organism | Structure |
---|---|---|---|
3,4-dimethyl-7-(2-phenoxyethoxy)-2H-chromen-2-one | pIC50 for MAO-A: 4.99; pIC50 for MAO-B: 7.57 | Rattus norvegicus | |
3,4-dimethyl-7-(2-phenylethyl)-2H-chromen-2-one | pIC50 for MAO-A: 5.15; pIC50 for MAO-B: 6.34 | Rattus norvegicus | |
3,4-dimethyl-7-phenoxy-2H-chromen-2-one | pIC50 for MAO-A: 4.5; pIC50 for MAO-B: 5.49 | Rattus norvegicus | |
7-(2-hydroxy-2-phenylethyloxy)-3,4-dimethyl-2H-chromen-2-one | - |
Rattus norvegicus | |
7-(3-chlorobenzyloxy)-3-methyl-2H-chromen-2-one | pIC50 for MAO-A: 4.9; pIC50 for MAO-B: 8.29 | Rattus norvegicus | |
7-(3-phenylprop-2-en-1-yloxy)-3,4-dimethyl-2H-chromen-2-one | pIC50 for MAO-A: 4.5; pIC50 for MAO-B: 6.95 | Rattus norvegicus | |
7-(benzenesulfonylmethoxy)-3,4-dimethyl-2H-chromen-2-one | pIC50 for MAO-A: 5.55; pIC50 for MAO-B: 6.06 | Rattus norvegicus | |
7-benzenesulfonyloxy-2H-chromen-2-one | pIC50 for MAO-A: 6.35; pIC50 for MAO-B: 4.26 | Rattus norvegicus | |
7-benzyloxy-3-methyl-2H-chromen-2-one | pIC50 for MAO-A: 5.26; pIC50 for MAO-B: 8.18 | Rattus norvegicus | |
7-benzylsulfonyl-3,4-dimethyl-2H-chromen-2-one | pIC50 for MAO-A: 4.73; pIC50 for MAO-B: 5.56 | Rattus norvegicus | |
7-benzylthio-3,4-dimethyl-2H-chromen-2-one | pIC50 for MAO-A: 5.0; pIC50 for MAO-B: 7.4 | Rattus norvegicus | |
benzoic acid (2H-2-oxochromen-7-yl)methyl ester | pIC50 for MAO-A: 5.02; pIC50 for MAO-B: 5.62 | Rattus norvegicus | |
N-(3,4-dimethyl-2H-2-oxochromen-7-yl)-N,4-dimethylbenzensulfonamide | pIC50 for MAO-A: 5.34; pIC50 for MAO-B: 4.5 | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Rattus norvegicus | 5739 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | P19643 | - |
- |
Rattus norvegicus | P21396 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
kynuramine + H2O + O2 | - |
Rattus norvegicus | 3-(2-aminophenyl)-3-oxopropanal + NH3 + H2O2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
MAO-A | - |
Rattus norvegicus |
MAO-B | - |
Rattus norvegicus |