Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P21397 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | MAOA activity and gene expression is upregulated in different brain areas of Alzheimer's disease patients, including the pineal gland. Alzheimer's disease patients carrying long MAOA-VNTR genotype (consisting of 3.5- or 4-repeat alleles) show higher MAOA gene expression and activity than the short-genotyped Alzheimer's disease patients (i.e., 3-repeat allele). MAOA-VNTR affects the activity and gene expression of MAOA in the brain of Alzheimer's disease patients, and is involved in the changes of monoamine metabolism | Homo sapiens | - |
pineal gland | MAOA activity and gene expression is upregulated in different brain areas of Alzheimer's disease patients, including the pineal gland. Increased pineal MAOA activity might contribute to the reduced pineal melatonin production in Alzheimer's disease. Alzheimer's disease patients carrying long MAOA-VNTR genotype (consisting of 3.5- or 4-repeat alleles) show higher MAOA gene expression and activity than the short-genotyped Alzheimer's disease patients (i.e., 3-repeat allele). MAOA-VNTR affects the activity and gene expression of MAOA in the brain of Alzheimer's disease patients, and is involved in the changes of monoamine metabolism | Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
MAOA | - |
Homo sapiens |
monoamine oxidase A | - |
Homo sapiens |