Literature summary for 1.4.3.4 extracted from

MacKenzie, E.M.; Fassihi, A.; Davood, A.; Chen, Q.H.; Rauw, G.; Rauw, G.; Knaus, E.E.; Baker, G.B.
N-Propynyl analogs of beta-phenylethylidenehydrazines: synthesis and evaluation of effects on glycine, GABA, and monoamine oxidase (2008), Bioorg. Med. Chem., 16, 8254-8263.

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Inhibitors

Inhibitors	Comment	Organism	Structure
(-)-deprenyl	-	Rattus norvegicus
beta-phenylethylidenehydrazine	a neuroprotective drug, inhibits MAO-A by 26.7%; a neuroprotective drug, inhibits MAO-B by 14.9%	Rattus norvegicus
Pargyline	-	Rattus norvegicus
Phenelzine	weak inhibition of MAO-A	Rattus norvegicus
rasagiline	-	Rattus norvegicus
[(E)-N-(2-propynyl)-2-(phenyl)ethylidene]-hydrazine	synthesis and inhibition of MAO isozymes, overview; synthesis and inhibition of MAO isozymes, overview	Rattus norvegicus
[(E)-N-bis-(2-propynyl)-2-(phenyl)ethyidene]hydrazine	synthesis and inhibition of MAO isozymes, overview; synthesis and inhibition of MAO isozymes, overview	Rattus norvegicus
[(Z)-N-(2-propynyl)-2-(phenyl)ethylidene]-hydrazine	synthesis and inhibition of MAO isozymes, overview; synthesis and inhibition of MAO isozymes, overview	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	P19643	-	-
Rattus norvegicus	P21936	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	-	Rattus norvegicus	-

Synonyms

Synonyms	Comment	Organism
MAO-A	-	Rattus norvegicus
MAO-B	-	Rattus norvegicus

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Release 2023.1 (January 2023)