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Literature summary for 1.4.3.4 extracted from
- Enzymologic characteristics of monoamine oxidase from liver of the skipjack tuna Katsuwonus pelamis (2013), J. Evol. Biochem. Physiol., 49, 562-569 .
No PubMed abstract available
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Acridine orange | irreversible inhibitor | Katsuwonus pelamis |  |
| Acriflavin | irreversible inhibitor | Katsuwonus pelamis | |
| additional information | the enzyme is not suppressed by 10 mM semicarbazide | Katsuwonus pelamis | |
| Proflavin | irreversible inhibitor | Katsuwonus pelamis | |
| pyronine G | irreversible inhibitor | Katsuwonus pelamis | |
| takrin | irreversible inhibitor | Katsuwonus pelamis | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.63 | - |
4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol | at pH 7.4 and 25°C | Katsuwonus pelamis | |
| 0.7 | - |
serotonin | at pH 7.4 and 25°C | Katsuwonus pelamis | |
| 4.71 | - |
dopamine | at pH 7.4 and 25°C | Katsuwonus pelamis | |
| 4.9 | - |
tryptamine | at pH 7.4 and 25°C | Katsuwonus pelamis | |
| 5.32 | - |
4-tyramine | at pH 7.4 and 25°C | Katsuwonus pelamis | |
| 6.43 | - |
N-methylhistamine | at pH 7.4 and 25°C | Katsuwonus pelamis | |
| 6.81 | - |
benzylamine | at pH 7.4 and 25°C | Katsuwonus pelamis | |
| 8.13 | - |
2-Phenylethylamine | at pH 7.4 and 25°C | Katsuwonus pelamis | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| mitochondrion | - |
Katsuwonus pelamis | 5739 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Katsuwonus pelamis | - |
skipjack tuna | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Katsuwonus pelamis | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 2-phenylethylamine + H2O + O2 | - |
Katsuwonus pelamis | 2-phenylethanal + NH3 + H2O2 | - |
? | |
| 4-tyramine + H2O + O2 | - |
Katsuwonus pelamis | (4-hydroxyphenyl)acetaldehyde + NH3 + H2O2 | - |
? | |
| benzylamine + H2O + O2 | - |
Katsuwonus pelamis | benzaldehyde + NH3 + H2O2 | - |
? | |
| dopamine + H2O + O2 | - |
Katsuwonus pelamis | (3,4-dihydroxyphenyl)acetaldehyde + NH3 + H2O2 | - |
? | |
| additional information | the enzyme does not deaminate histamine | Katsuwonus pelamis | ? | - |
? | |
| N-methylhistamine + H2O + O2 | - |
Katsuwonus pelamis | 1H-imidazol-4-ylacetaldehyde + methylamine + H2O2 | - |
? | |
| noradrenaline + H2O + O2 | - |
Katsuwonus pelamis | (2R)-(3,4-dihydroxyphenyl)(hydroxy)acetaldehyde + NH3 + H2O2 | - |
? | |
| serotonin + H2O + O2 | - |
Katsuwonus pelamis | (5-hydroxy-1H-indol-3-yl)acetaldehyde + NH3 + H2O2 | - |
? | |
| tryptamine + H2O + O2 | - |
Katsuwonus pelamis | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| MAO | - |
Katsuwonus pelamis |
| monoamine: O2-oxidoreductase: deaminating | - |
Katsuwonus pelamis |
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