Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.5.1.17 extracted from

  • Fields, J.H.A.; Storey, K.B.
    Tissue-specific alanopine dehydrogenase from the gill and strombine dehydrogenase from the foot muscle of the cherrystone clam Mercenaria mercenaria (1987), J. Exp. Mar. Biol. Ecol., 105, 175-185.
No PubMed abstract available
Search for more literature for 1.5.1.17

Inhibitors

Inhibitors Comment Organism Structure
D-lactate weak Mercenaria mercenaria
L-lactate weak Mercenaria mercenaria
meso-Alanopine weak Mercenaria mercenaria
succinate weak Mercenaria mercenaria

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.38
-
 pyruvate
-
 Mercenaria mercenaria
2.5
-
 2-oxobutyrate
-
 Mercenaria mercenaria
11.9
-
 glyoxylate
-
 Mercenaria mercenaria
15
-
 L-2-aminobutyrate
-
 Mercenaria mercenaria
15.1
-
 L-Ala
-
 Mercenaria mercenaria
20
-
 L-Val
-
 Mercenaria mercenaria
23
-
 L-Cys
-
 Mercenaria mercenaria
28
-
 L-Ala
-
 Mercenaria mercenaria
110
-
 L-Thr
-
 Mercenaria mercenaria
247
-
 L-Ser
-
 Mercenaria mercenaria
291
-
 Gly
-
 Mercenaria mercenaria

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mercenaria mercenaria the enzyme functions as the terminal dehydrogenase of glycolysis and has a role in maintaining energy production under the stresses of environmental or functional anoxia ?
-
 ?

Organism

Organism UniProt Comment Textmining
Mercenaria mercenaria
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial Mercenaria mercenaria

Source Tissue

Source Tissue Comment Organism Textmining
gill
-
 Mercenaria mercenaria
-
mantle
-
 Mercenaria mercenaria
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Gly + pyruvate + NADH at 69% of the activity with L-Ala Mercenaria mercenaria Strombine + NAD+ + H2O
-
 ?
L-2-Aminobutyrate + pyruvate + NADH at 94% of the activity with L-Ala Mercenaria mercenaria ?
-
 ?
L-Ala + 2-oxobutanoate + NADH at 22% the activity with pyruvate Mercenaria mercenaria ?
-
 ?
L-Ala + glyoxylate + NADH at 44% the activity with pyruvate Mercenaria mercenaria ?
-
 ?
L-Ala + pyruvate + NADH
-
 Mercenaria mercenaria 2,2'-Iminodipropanoate + NAD+ + H2O
-
 ?
L-Cys + pyruvate + NADH at 90% of the activity with L-Ala Mercenaria mercenaria ?
-
 ?
L-Ser + pyruvate + NADH at 90% of the activity with L-Ala Mercenaria mercenaria ?
-
 ?
L-Thr + pyruvate + NADH at 62% of the activity with L-Ala Mercenaria mercenaria ?
-
 ?
L-Val + pyruvate + NADH at 65% of the activity with L-Ala Mercenaria mercenaria ?
-
 ?
additional information the enzyme functions as the terminal dehydrogenase of glycolysis and has a role in maintaining energy production under the stresses of environmental or functional anoxia Mercenaria mercenaria ?
-
 ?

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Mercenaria mercenaria
NADH
-
 Mercenaria mercenaria