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Literature summary for 1.5.1.23 extracted from
- Tauropine dehydrogenase from the starfish Asterina pectinifera (echinodermata: asteroidea): presence of opine production pathway in a deuterostome invertebrate (1998), Comp. Biochem. Physiol. B, 121, 323-332.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| tauropine | - |
Patiria pectinifera |  |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| additional information | - |
additional information | effect of cosubstrate concentration on the Km-value of tauropine and pyruvate | Patiria pectinifera | |
| 0.054 | - |
NADH | - |
Patiria pectinifera | |
| 0.068 | - |
pyruvate | NAD+ | Patiria pectinifera | |
| 0.46 | - |
pyruvate | - |
Patiria pectinifera | |
| 2.64 | - |
tauropine | - |
Patiria pectinifera | |
| 21.3 | - |
taurine | - |
Patiria pectinifera | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 41300 | - |
1 * 41300, SDS-PAGE | Patiria pectinifera |
| 42400 | - |
gel filtration | Patiria pectinifera |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Patiria pectinifera | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Patiria pectinifera |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| body wall | - |
Patiria pectinifera | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 551.8 | - |
- |
Patiria pectinifera |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Homotaurine + pyruvate + NADH | at 32.1% of the activity with taurine | Patiria pectinifera | ? | - |
? | |
| Hypotaurine + pyruvate + NADH | at 21.2% of the activity with taurine | Patiria pectinifera | N2-(1-Carboxyethyl)aminoethanesulfinic acid + NAD+ + H2O | - |
? | |
| Taurine + 2-oxobutanoate + NADH | at 4.4% of the activity with pyruvate | Patiria pectinifera | ? | - |
? | |
| Taurine + glyoxylate + NADH | at 6.8% of the activity with pyruvate | Patiria pectinifera | ? | - |
? | |
| taurine + oxaloacetate + NADH | at 78.1% of the activity with pyruvate | Patiria pectinifera | ? | - |
? | |
| Taurine + pyruvate + NADH | - |
Patiria pectinifera | Tauropine + NAD+ + H2O | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| monomer | 1 * 41300, SDS-PAGE | Patiria pectinifera |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 6 | - |
tauropine formation | Patiria pectinifera |
| 8.7 | 9.2 | tauropone oxidation | Patiria pectinifera |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 5.1 | 7.2 | 50% of maximal activity at pH 5.1 and at pH 7.2, tauropine formation | Patiria pectinifera |
| 8.7 | 9.2 | 50% of maximal activity at pH 8.7 and at pH 9.2, tauropine oxidation | Patiria pectinifera |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NADH | - |
Patiria pectinifera | |
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Release 2023.1 (January 2023)
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