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Literature summary for 1.5.1.3 extracted from

  • Spina, M.; Cuccioloni, M.; Mozzicafreddo, M.; Montecchia, F.; Pucciarelli, S.; Eleuteri, A.M.; Fioretti, E.; Angeletti, M.
    Mechanism of inhibition of wt-dihydrofolate reductase from E. coli by tea epigallocatechin-gallate (2008), Proteins, 72, 240-251.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
epigallocatechin gallate bisubstrate inhibitor, binds both on substrate and cofactor site of dihydrofolate reductase. Detailed study on kinetics Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli
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