KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.4 | - |
L-lysine | enzyme from L3 larva, at pH 7.0, temperature not specified in the publication | Haemonchus contortus | |
0.5 | - |
L-lysine | enzyme from L3 larva, at pH 7.0, temperature not specified in the publication | Teladorsagia circumcincta | |
0.7 | - |
L-lysine | enzyme from adult, at pH 7.0, temperature not specified in the publication | Haemonchus contortus | |
0.9 | - |
L-lysine | enzyme from adult, at pH 7.0, temperature not specified in the publication | Teladorsagia circumcincta |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | 0.5 mM Ca+ used in assay conditions | Haemonchus contortus | |
Ca2+ | 0.5 mM Ca+ used in assay conditions | Teladorsagia circumcincta |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-lysine + 2-oxoglutarate + NADH + H+ | Haemonchus contortus | - |
N6-(L-1,3-dicarboxypropyl)-L-lysine + NAD+ + H2O | - |
? | |
L-lysine + 2-oxoglutarate + NADH + H+ | Teladorsagia circumcincta | - |
N6-(L-1,3-dicarboxypropyl)-L-lysine + NAD+ + H2O | - |
? | |
L-lysine + 2-oxoglutarate + NADPH + H+ | Haemonchus contortus | - |
N6-(L-1,3-dicarboxypropyl)-L-lysine + NADP+ + H2O | - |
? | |
L-lysine + 2-oxoglutarate + NADPH + H+ | Teladorsagia circumcincta | - |
N6-(L-1,3-dicarboxypropyl)-L-lysine + NADP+ + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Haemonchus contortus | - |
- |
- |
Teladorsagia circumcincta | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adult | - |
Haemonchus contortus | - |
adult | - |
Teladorsagia circumcincta | - |
larva | - |
Haemonchus contortus | - |
larva | - |
Teladorsagia circumcincta | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-lysine + 2-oxoglutarate + NADH + H+ | - |
Haemonchus contortus | N6-(L-1,3-dicarboxypropyl)-L-lysine + NAD+ + H2O | - |
? | |
L-lysine + 2-oxoglutarate + NADH + H+ | - |
Teladorsagia circumcincta | N6-(L-1,3-dicarboxypropyl)-L-lysine + NAD+ + H2O | - |
? | |
L-lysine + 2-oxoglutarate + NADPH + H+ | - |
Haemonchus contortus | N6-(L-1,3-dicarboxypropyl)-L-lysine + NADP+ + H2O | - |
? | |
L-lysine + 2-oxoglutarate + NADPH + H+ | - |
Teladorsagia circumcincta | N6-(L-1,3-dicarboxypropyl)-L-lysine + NADP+ + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
LKR | - |
Haemonchus contortus |
LKR | - |
Teladorsagia circumcincta |
lysine ketoglutarate reductase | - |
Haemonchus contortus |
lysine ketoglutarate reductase | - |
Teladorsagia circumcincta |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7 | - |
- |
Haemonchus contortus |
7 | - |
- |
Teladorsagia circumcincta |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | dual co-factor enzyme, not specific for either NAD+ or NADP+ | Haemonchus contortus | |
NAD+ | dual co-factor enzyme, not specific for either NAD+ or NADP+ | Teladorsagia circumcincta | |
NADP+ | dual co-factor enzyme, not specific for either NAD+ or NADP+ | Haemonchus contortus | |
NADP+ | dual co-factor enzyme, not specific for either NAD+ or NADP+ | Teladorsagia circumcincta |