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Literature summary for 1.5.3.1 extracted from
- Steady-state kinetics and spectral properties of Corynebacterium sarcosine oxidase (1983), Biochim. Biophys. Acta, 742, 630-646 .
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| acetic acid | - |
Corynebacterium sp. U-96 |  |
| Ag+ | marked inhibition at 1 mM | Corynebacterium sp. U-96 | |
| Cd2+ | marked inhibition at 1 mM | Corynebacterium sp. U-96 | |
| Cu2+ | marked inhibition at 1 mM | Corynebacterium sp. U-96 | |
| glycine | - |
Corynebacterium sp. U-96 | |
| Hg2+ | - |
Corynebacterium sp. U-96 | |
| iodoacetic acid | - |
Corynebacterium sp. U-96 | |
| Methoxyacetic acid | - |
Corynebacterium sp. U-96 | |
| Pb2+ | marked inhibition at 1 mM | Corynebacterium sp. U-96 | |
| propionic acid | - |
Corynebacterium sp. U-96 | |
| Zn2+ | marked inhibition at 1 mM | Corynebacterium sp. U-96 | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.25 | - |
O2 | at pH 8.0 and 30°C | Corynebacterium sp. U-96 | |
| 21 | - |
sarcosine | at pH 8.0 and 30°C | Corynebacterium sp. U-96 | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| sarcosine + H2O + O2 | Corynebacterium sp. U-96 | - |
glycine + formaldehyde + H2O2 | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Corynebacterium sp. U-96 | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| sarcosine + H2O + O2 | - |
Corynebacterium sp. U-96 | glycine + formaldehyde + H2O2 | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| sarcosine : oxygen oxidoreductase (demethylating) | - |
Corynebacterium sp. U-96 |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| FAD | - |
Corynebacterium sp. U-96 | |
IC50 Value
| IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
|---|---|---|---|---|---|
| 25 | - |
at pH 8.0 and 30°C | Corynebacterium sp. U-96 | acetic acid | |
| 35 | - |
at pH 8.0 and 30°C | Corynebacterium sp. U-96 | propionic acid | |
| 35 | - |
at pH 8.0 and 30°C | Corynebacterium sp. U-96 | Methoxyacetic acid | |
| 200 | - |
IC50 above 200 mM, at pH 8.0 and 30°C | Corynebacterium sp. U-96 | glycine | |
| 200 | - |
IC50 equal or less 200 mM, at pH 8.0 and 30°C | Corynebacterium sp. U-96 | iodoacetic acid | |
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