Application | Comment | Organism |
---|---|---|
medicine | L-pipecolic acid is formed by the catabolism of lysine in humans, and its accumulation is one of the first biochemical abnormalities detected in the Zellweger syndrome | Homo sapiens |
medicine | the L-pipecolate pathway for degradation of lysine is the principal one in the brain | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
expressed as a chimera between maltose-binding protein and L-pipecolic acid oxidase | Homo sapiens |
expressed in Escherichia coli BL21 | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-pipecolate + O2 | Homo sapiens | - |
2,3,4,5-tetrahydropyridine-2-carboxylate + H2O2 | the product reacts with water to form 2-aminoadipate 6-semialdehyde | ? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-pipecolate + O2 | - |
Homo sapiens | 2,3,4,5-tetrahydropyridine-2-carboxylate + H2O2 | the product reacts with water to form 2-aminoadipate 6-semialdehyde | ? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8.7 | - |
assay at | Homo sapiens |