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Literature summary for 1.5.8.2 extracted from

  • C๖lfen, H.; Harding, S.E.; Wilson, E.K.; Packman, L.C.; Scrutton, N.S.
    Homodimeric and expanded behaviour of trimethylamine dehydrogenase in solution at different temperatures (1996), Biophys. J., 24, 159-164.
No PubMed abstract available

Metals/Ions

Metals/Ions Comment Organism Structure
Fe 4Fe-4S-center Methylophilus methylotrophus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
163000
-
gel filtration Methylophilus methylotrophus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
trimethylamine + H2O + electron transferring flavoprotein Methylophilus methylotrophus
-
dimethylamine + formaldehyde + reduced electron transferring flavoprotein
-
?
trimethylamine + H2O + electron transferring flavoprotein Methylophilus methylotrophus W3A1
-
dimethylamine + formaldehyde + reduced electron transferring flavoprotein
-
?

Organism

Organism UniProt Comment Textmining
Methylophilus methylotrophus
-
-
-
Methylophilus methylotrophus W3A1
-
-
-

Purification (Commentary)

Purification (Comment) Organism
to homogeneity, chromatography steps Methylophilus methylotrophus

Source Tissue

Source Tissue Comment Organism Textmining
cell culture
-
Methylophilus methylotrophus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
trimethylamine + H2O + electron transferring flavoprotein
-
Methylophilus methylotrophus dimethylamine + formaldehyde + reduced electron transferring flavoprotein
-
?
trimethylamine + H2O + electron transferring flavoprotein
-
Methylophilus methylotrophus W3A1 dimethylamine + formaldehyde + reduced electron transferring flavoprotein
-
?

Subunits

Subunits Comment Organism
dimer consistent with molecular mass calculation from X-ray data Methylophilus methylotrophus

Cofactor

Cofactor Comment Organism Structure
FMN
-
Methylophilus methylotrophus