Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | forward reaction stimulated by proton gradient from respiratory chain | Mus musculus | |
additional information | forward reaction stimulated by proton gradient from respiratory chain | Homo sapiens | |
additional information | forward reaction stimulated by proton gradient from respiratory chain | Caenorhabditis elegans |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrial inner membrane | - |
Mus musculus | 5743 | - |
mitochondrial inner membrane | - |
Homo sapiens | 5743 | - |
mitochondrial inner membrane | - |
Caenorhabditis elegans | 5743 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
NADH + NADP+ | Mus musculus | links hydride transfer between NAD(H) and NADP(H) to the translocation of protons across membrane, important for the oxidative stress defense | NAD+ + NADPH | - |
r | |
NADH + NADP+ | Homo sapiens | links hydride transfer between NAD(H) and NADP(H) to the translocation of protons across membrane, important for the oxidative stress defense | NAD+ + NADPH | - |
r | |
NADH + NADP+ | Caenorhabditis elegans | links hydride transfer between NAD(H) and NADP(H) to the translocation of protons across membrane, important for the oxidative stress defense | NAD+ + NADPH | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Caenorhabditis elegans | - |
- |
- |
Homo sapiens | - |
- |
- |
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adrenal gland | - |
Mus musculus | - |
bladder | - |
Mus musculus | - |
brain | - |
Mus musculus | - |
brain | - |
Homo sapiens | - |
caudate putamen | - |
Homo sapiens | - |
cerebellum | - |
Homo sapiens | - |
cerebral cortex | - |
Homo sapiens | - |
frontal lobe | - |
Homo sapiens | - |
gut | very strong expression | Caenorhabditis elegans | - |
heart | highest expression level | Mus musculus | - |
kidney | - |
Mus musculus | - |
liver | - |
Mus musculus | - |
lung | - |
Mus musculus | - |
medulla oblongata | - |
Homo sapiens | - |
additional information | ubiquitous enzyme present in virtually all animal tissues | Mus musculus | - |
occipital pole | - |
Homo sapiens | - |
ovary | - |
Mus musculus | - |
pancreas | - |
Mus musculus | - |
spinal cord | - |
Homo sapiens | - |
temporal lobe | - |
Homo sapiens | - |
testis | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
NADH + NADP+ | - |
Mus musculus | NAD+ + NADPH | - |
r | |
NADH + NADP+ | - |
Homo sapiens | NAD+ + NADPH | - |
r | |
NADH + NADP+ | - |
Caenorhabditis elegans | NAD+ + NADPH | - |
r | |
NADH + NADP+ | links hydride transfer between NAD(H) and NADP(H) to the translocation of protons across membrane, important for the oxidative stress defense | Mus musculus | NAD+ + NADPH | - |
r | |
NADH + NADP+ | links hydride transfer between NAD(H) and NADP(H) to the translocation of protons across membrane, important for the oxidative stress defense | Homo sapiens | NAD+ + NADPH | - |
r | |
NADH + NADP+ | links hydride transfer between NAD(H) and NADP(H) to the translocation of protons across membrane, important for the oxidative stress defense | Caenorhabditis elegans | NAD+ + NADPH | - |
r |
Synonyms | Comment | Organism |
---|---|---|
proton-translocating nicotinamide nucleotide transhydrogenase | - |
Mus musculus |
proton-translocating nicotinamide nucleotide transhydrogenase | - |
Homo sapiens |
proton-translocating nicotinamide nucleotide transhydrogenase | - |
Caenorhabditis elegans |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD(P)+ | - |
Mus musculus | |
NAD(P)+ | - |
Homo sapiens | |
NAD(P)+ | - |
Caenorhabditis elegans | |
NAD(P)H | - |
Mus musculus | |
NAD(P)H | - |
Homo sapiens | |
NAD(P)H | - |
Caenorhabditis elegans |