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Literature summary for 1.6.1.2 extracted from
- Converting NADH to NAD+ by nicotinamide nucleotide transhydrogenase as a novel strategy against mitochondrial pathologies during aging (2009), Biogerontology, 10, 531-534.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | NNT expression is 2.8fold downregulated in the vastus lateralis muscle of calorie restricted rhesus monkeys | Macaca mulatta |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| mitochondrial inner membrane | - |
Mus musculus | 5743 | - |
| mitochondrial inner membrane | - |
Caenorhabditis elegans | 5743 | - |
| mitochondrial inner membrane | - |
Macaca mulatta | 5743 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Caenorhabditis elegans | - |
- |
- |
| Macaca mulatta | - |
- |
- |
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| muscle | - |
Macaca mulatta | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| NADP+ + NADH | - |
Mus musculus | NADPH + NAD+ | - |
r |  |
| NADP+ + NADH | - |
Caenorhabditis elegans | NADPH + NAD+ | - |
r | |
| NADP+ + NADH | - |
Macaca mulatta | NADPH + NAD+ | - |
r | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| nicotinamide nucleotide transhydrogenase | - |
Mus musculus |
| nicotinamide nucleotide transhydrogenase | - |
Caenorhabditis elegans |
| nicotinamide nucleotide transhydrogenase | - |
Macaca mulatta |
| NNT | - |
Mus musculus |
| NNT | - |
Caenorhabditis elegans |
| NNT | - |
Macaca mulatta |
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Release 2023.1 (January 2023)
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