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Literature summary for 1.6.2.2 extracted from

  • Amdahl, M.B.; Petersen, E.E.; Bocian, K.; Kaliszuk, S.J.; DeMartino, A.W.; Tiwari, S.; Sparacino-Watkins, C.E.; Corti, P.; Rose, J.J.; Gladwin, M.T.; Fago, A.; Tejero, J.
    The zebrafish cytochrome b5/cytochrome b5 reductase/NADH system efficiently reduces cytoglobins 1 and 2 conserved activity of cytochrome b5/cytochrome b5 reductases during vertebrate evolution (2019), Biochemistry, 58, 3212-3223 .
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Danio rerio Q6NYE6
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ferricytochrome b5 + cytoglobin 1
-
Danio rerio ferrocytochrome b5 + ?
-
?
ferricytochrome b5 + cytoglobin 2
-
Danio rerio ferrocytochrome b5 + ?
-
?
ferricytochrome b5 + globin x
-
Danio rerio ferrocytochrome b5 + ?
-
?

General Information

General Information Comment Organism
metabolism the zebrafish cytochrome b5 reductase reduces zebrafish heme proteins cytoglobin 1 and 2 in presence of the two zebrafish cytochrome b5 isoforms. The reducing system also supports reduction of globin X, a conserved globin in fish and amphibians. The P50 for oxygen is 0.5 Torr for cytoglobin 1 and 4.4 Torr for cytoglobin 2 at 25°C Danio rerio