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Literature summary for 1.6.2.4 extracted from

  • Wang, Y.; Gray, J.P.; Mishin, V.; Heck, D.E.; Laskin, D.L.; Laskin, J.D.
    Role of cytochrome P450 reductase in nitrofurantoin-induced redox cycling and cytotoxicity (2008), Free Radic. Biol. Med., 44, 1169-1179.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
medicine nitrofurantoin-induced redox cycling and subsequent generation of reactive oxygen intermediates are not sufficient to mediate cytotoxicity. Cytochrome P450 reductase is not a determinant of sensitivity to redox-active chemotherapeutic agents Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
recombinant
-

Synonyms

Synonyms Comment Organism
cytochrome P450 reductase
-
Rattus norvegicus