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Literature summary for 1.6.2.4 extracted from

  • Song, W.; Yan, S.; Li, Y.; Feng, S.; Zhang, J.J.; Li, J.R.
    Functional characterization of squalene epoxidase and NADPH-cytochrome P450 reductase in Dioscorea zingiberensis (2019), Biochem. Biophys. Res. Commun., 509, 822-827 .
    View publication on PubMed
Search for more literature for 1.6.2.4

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Dioscorea zingiberensis

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0129
-
 NADPH pH 7.6, 25°C Dioscorea zingiberensis
0.0159
-
 ferricytochrome c pH 7.6, 25°C Dioscorea zingiberensis

Localization

Localization Comment Organism GeneOntology No. Textmining
endoplasmic reticulum
-
 Dioscorea zingiberensis 5783
-

Organism

Organism UniProt Comment Textmining
Dioscorea zingiberensis
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
flower the highest level of CPR expression is found in mature leaves followed by flowers, young leaves, rhizomes, and stems Dioscorea zingiberensis
-
leaf the highest level of CPR expression is found in mature leaves followed by flowers, young leaves, rhizomes, and stems Dioscorea zingiberensis
-
rhizome the highest level of CPR expression is found in mature leaves followed by flowers, young leaves, rhizomes, and stems Dioscorea zingiberensis
-
stem the highest level of CPR expression is found in mature leaves followed by flowers, young leaves, rhizomes, and stems Dioscorea zingiberensis
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2 ferricytochrome c + NADPH + H+
-
 Dioscorea zingiberensis 2 ferrocytochrome c + NADP+
-
 ?

General Information

General Information Comment Organism
physiological function squalene epoxidase catalyzes the epoxidation of squalene in coordination with NADPH-cytochrome P450 reductase CPR. When squalene epoxidase and CPR are incubated with the substrates squalene and NADPH, 2,3-oxidosqualene is formed as the product Dioscorea zingiberensis