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Literature summary for 1.6.3.1 extracted from

  • Marcal, L.E.; Dias-da-Motta, P.M.; Rehder, J.; Mamoni, R.L.; Blotta, M.H.; Whitney, C.B.; Newburger, P.E.; Costa, F.F.; Saad, S.T.; Condino-Neto, A.
    Up-regulation of NADPH oxidase components and increased production of interferon-gamma by leukocytes from sickle cell disease patients (2008), Am. J. Hematol., 83, 41-45.
    View publication on PubMed

Application

Application Comment Organism
medicine monocytes from sickle cell disease patients show higher levels of NAD(P)H oxidase subunit gp91phox gene expression and p47phox phosphorylation, along with increased interferon-gamma release by lymphocytes Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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patients with sickle cell disease
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Source Tissue

Source Tissue Comment Organism Textmining
monocyte subunit gp91phox gene expression is significantly higher in monocytes from sickle cell disease patients compared with normal controls. Monocytes from patients show higher levels of p47phox phosphorylation compared with normal controls Homo sapiens
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