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Literature summary for 1.6.3.1 extracted from
- Characterisation of electron currents generated by the human neutrophil NADPH oxidase (2008), Biochem. Biophys. Res. Commun., 368, 656-661.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| diphenyleneiodonium | inhibition of NAD(P)H oxidase abolishes depolarisation of the neutrophil plasma membrane by electron current | Homo sapiens |  |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| membrane | the electron current depolarises the neutrophil plasma membrane at a rate of 2.3 V per s and this depolarisation is opposed when voltage-gated proton channels are activated. 3 mM ZnCl2 depolarises the membrane potential to +97.8 mV , and this depolarisation is abolished after NADPH oxidase inhibition | Homo sapiens | 16020 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| neutrophil | - |
Homo sapiens | - |
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Release 2023.1 (January 2023)
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