Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | A7RDN6 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adrenal gland | substantial expression cortex of adrenal gland | Mus musculus | - |
granulosa cell | substantial expression in granulosa | Mus musculus | - |
additional information | renalase is predominantly expressed in reproductive/steroidogenic systems, with particularly substantial expression in oocytes, granulosa, interstitial and luteal cells of ovary, spermatogenic cells of testis, and cortex of adrenal gland | Mus musculus | - |
oocyte | substantial expression in oocytes | Mus musculus | - |
ovary | substantial expression in interstitial and luteal cells of ovary. Expression increases in testes and ovaries as mice develop and is further enhanced in the ovaries of pregnant mice | Mus musculus | - |
testis | substantial expression spermatogenic cells of testis. Expression increases in testes and ovaries as mice develop | Mus musculus | - |
Organism | Comment | Expression |
---|---|---|
Mus musculus | gonadotropin-releasing hormone antagonist, cetrorelix, represses renalase expression in mice ovaries and testes | down |
Mus musculus | knockout of leptin, an effector and modulator of steroid hormones and reproduction, causes a dramatic increase of renalase expression in mice testes | up |