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Literature summary for 1.6.5.2 extracted from

  • Newsome, J.J.; Hassani, M.; Swann, E.; Bibby, J.M.; Beall, H.D.; Moody, C.J.
    Benzofuran-, benzothiophene-, indazole- and benzisoxazole-quinones excellent substrates for NAD(P)H quinone oxidoreductase 1 (2013), Bioorg. Med. Chem., 21, 2999-3009 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.6.5.2

Cloned(Commentary)

Cloned (Comment) Organism
-
 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P15559
-
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
38.1
-
 substrate 3-(hydroxymethyl)-5-methoxy-1-methyl-1H-indazole-4,7-dione, pH 7.4, 22°C Homo sapiens
53.9
-
 substrate methyl 5-methoxy-4,7-dioxo-4,7-dihydro-1-benzothiophene-2-carboxylate, pH 7.4, 22°C Homo sapiens
63.8
-
 substrate 5-methoxy-4,7-dioxo-4,7-dihydro-1-benzothiophene-2-carboxylic acid, pH 7.4, 22°C Homo sapiens
80.8
-
 substrate 2-(1-hydroxyethyl)-5-methoxy-3-methyl-1-benzofuran-4,7-dione, pH 7.4, 22°C Homo sapiens
87.9
-
 substrate 3-(1-hydroxyethyl)-5-methoxy-2-methyl-1-benzofuran-4,7-dione, pH 7.4, 22°C Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-(1-hydroxyethyl)-5-methoxy-3-methyl-1-benzofuran-4,7-dione + NADH + H+
-
 Homo sapiens 2-(1-hydroxyethyl)-5-methoxy-3-methyl-1-benzofuran-4,7-diol + NAD+
-
 ?
3-(1-hydroxyethyl)-5-methoxy-2-methyl-1-benzofuran-4,7-dione + NADH + H+
-
 Homo sapiens 3-(1-hydroxyethyl)-5-methoxy-2-methyl-1-benzofuran-4,7-diol + NAD+
-
 ?
3-(hydroxymethyl)-5-methoxy-1-methyl-1H-indazole-4,7-dione + NADH + H+
-
 Homo sapiens 3-(hydroxymethyl)-5-methoxy-1-methyl-1H-indazole-4,7-diol + NAD+
-
 ?
5-methoxy-4,7-dioxo-4,7-dihydro-1-benzothiophene-2-carboxylic acid + NADH + H+
-
 Homo sapiens 4,7-dihydroxy-5-methoxy-1-benzothiophene-2-carboxylic acid + NAD+
-
 ?
methyl 5-methoxy-4,7-dioxo-4,7-dihydro-1-benzothiophene-2-carboxylate + NADH + H+
-
 Homo sapiens methyl 4,7-dihydroxy-5-methoxy-1-benzothiophene-2-carboxylate + NAD+
-
 ?