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Literature summary for 1.6.5.9 extracted from

  • Kerscher, S.; Okun, J.; Brandt, U.
    A single external enzyme confers alternative NADH:ubiquinone oxidoreductase activity in Yarrowia lipolytica (1999), J. Cell Sci., 112, 2347-2354.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
additional information not inhibited by piericidin A. Addition of up to 10% (v/v) ethanol has no effect on NADH:NBQ oxidoreductase activity Yarrowia lipolytica

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.014
-
NADH pH and temperature not specified in the publication Yarrowia lipolytica

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrial membrane NDH2 is oriented towards the external face of the mitochondrial inner membrane Yarrowia lipolytica 31966
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
65800
-
calculated from amino acid sequence Yarrowia lipolytica

Organism

Organism UniProt Comment Textmining
Yarrowia lipolytica
-
-
-
Yarrowia lipolytica E 150
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information alternative NADH:ubiquinone oxidoreductase does not pump protons across the inner mitochondrial membrane Yarrowia lipolytica ?
-
?
additional information alternative NADH:ubiquinone oxidoreductase does not pump protons across the inner mitochondrial membrane Yarrowia lipolytica E 150 ?
-
?
NADH + H+ + 5-nonylubiquinone
-
Yarrowia lipolytica NAD+ + 5-nonylubiquinol
-
?
NADH + H+ + 5-nonylubiquinone
-
Yarrowia lipolytica E 150 NAD+ + 5-nonylubiquinol
-
?

Synonyms

Synonyms Comment Organism
alternative NADH:ubiquinone oxidoreductase
-
Yarrowia lipolytica
external NADH:ubiquinone oxidoreductase
-
Yarrowia lipolytica
NDH2
-
Yarrowia lipolytica

Cofactor

Cofactor Comment Organism Structure
NADH
-
Yarrowia lipolytica

General Information

General Information Comment Organism
malfunction strains carrying the deletion of NDH2 are completely viable Yarrowia lipolytica