Literature summary for 1.6.99.1 extracted from

De-Faria, M.H.; do-Nascimento, J.L.M.; Paes-de-Carvalho, R.
Biochemical characterization of NADPH-diaphorase in the chick embryo retina: Stimulation by calcium ions and inhibition by arginine analogs (1995), Braz. J. Med. Biol. Res., 28, 252-255.

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Inhibitors

Inhibitors	Comment	Organism	Structure
EDTA	-	Gallus gallus
EGTA	-	Gallus gallus
L-N5-(1-iminoethyl)Orn	1 mM 63% inhibition	Gallus gallus
monomethyl-L-Arg acetate	1 mM, 14% inhibition	Gallus gallus
NG-nitro-L-Arg	3 mM, 53% inhibition	Gallus gallus
Ngamma-monomethyl-L-Arg	1 mM, 14% inhibition	Gallus gallus

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Ca2+	2 mM CaCl2, 48% stimulates. The effect is reversed by 1 mM EGTA or EDTA	Gallus gallus

Organism

Organism	UniProt	Comment	Textmining
Gallus gallus	-	diaphorase activity of nitric oxide synthase	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
embryo	retina	Gallus gallus	-
retina	from embryo	Gallus gallus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
NADPH + acceptor	acceptor: nitroblue tetrazolium hydrochloride	Gallus gallus	NADP+ + reduced acceptor	-	?

Synonyms

Synonyms	Comment	Organism
nitric oxide synthase	identical to	Gallus gallus

Cofactor

Cofactor	Comment	Organism	Structure
NADPH	-	Gallus gallus

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Release 2023.1 (January 2023)