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Literature summary for 1.7.1.10 extracted from

  • Bernheim, M.L.C.
    The reduction of hydroxylamine and some aryl hydroxamates by liver mitochondria from mammals and birds (1972), Enzymologia, 43, 167-176.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
Bromelain
-
Rattus norvegicus
butanol
-
Rattus norvegicus
CaCl2 reactivation by washing Rattus norvegicus
deoxycholic acid
-
Rattus norvegicus
Duponol C
-
Rattus norvegicus
ethanol
-
Rattus norvegicus
KCl reactivation by washing Rattus norvegicus
Murine phospholipase
-
Rattus norvegicus
N-Methyl hydroxylamine
-
Rattus norvegicus
NaCl reactivation by washing Rattus norvegicus
papain
-
Rattus norvegicus
phosphate
-
Rattus norvegicus
Propanol
-
Rattus norvegicus
Sodium arsenate
-
Rattus norvegicus
Subtilopeptidase A
-
Rattus norvegicus
Trypsin
-
Rattus norvegicus
Uranyl acetate ATP, ADP, sodium diphosphate restores activity Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane firmly attached to mitochondrial membrane Rattus norvegicus 16020
-
mitochondrion
-
Mus musculus 5739
-
mitochondrion
-
Sus scrofa 5739
-
mitochondrion
-
Oryctolagus cuniculus 5739
-
mitochondrion
-
Ovis aries 5739
-
mitochondrion
-
Didelphidae 5739
-
mitochondrion firmly attached to membrane Rattus norvegicus 5739
-

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-
Canis lupus familiaris
-
-
-
Cavia porcellus
-
-
-
Cricetinae
-
-
-
Didelphidae
-
very low activity
-
Gallus gallus
-
-
-
Mus musculus
-
-
-
no activity in Amphibia
-
-
-
no activity in fish
-
-
-
no activity in reptilia
-
-
-
Oryctolagus cuniculus
-
-
-
Ovis aries
-
-
-
Pigeon
-
-
-
Rattus norvegicus
-
-
-
Sus scrofa
-
-
-

Reaction

Reaction Comment Organism Reaction ID
NH3 + NAD+ + H2O = hydroxylamine + NADH + H+ also acts on hydroxamates Gallus gallus
NH3 + NAD+ + H2O = hydroxylamine + NADH + H+ also acts on hydroxamates Cavia porcellus
NH3 + NAD+ + H2O = hydroxylamine + NADH + H+ also acts on hydroxamates Mus musculus
NH3 + NAD+ + H2O = hydroxylamine + NADH + H+ also acts on hydroxamates Rattus norvegicus
NH3 + NAD+ + H2O = hydroxylamine + NADH + H+ also acts on hydroxamates Bos taurus
NH3 + NAD+ + H2O = hydroxylamine + NADH + H+ also acts on hydroxamates Oryctolagus cuniculus
NH3 + NAD+ + H2O = hydroxylamine + NADH + H+ also acts on hydroxamates Ovis aries
NH3 + NAD+ + H2O = hydroxylamine + NADH + H+ also acts on hydroxamates Pigeon
NH3 + NAD+ + H2O = hydroxylamine + NADH + H+ also acts on hydroxamates Canis lupus familiaris
NH3 + NAD+ + H2O = hydroxylamine + NADH + H+ also acts on hydroxamates Didelphidae
NH3 + NAD+ + H2O = hydroxylamine + NADH + H+ also acts on hydroxamates Cricetinae

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Mus musculus
-
liver
-
Rattus norvegicus
-
liver
-
Sus scrofa
-
liver
-
Oryctolagus cuniculus
-
liver
-
Ovis aries
-
liver
-
Canis lupus familiaris
-
liver
-
Didelphidae
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
anthranillic hydroxamate + NADH + H+ activity in liver mitochondria Gallus gallus anthranilamide + NAD+ + H2O
-
?
anthranillic hydroxamate + NADH + H+ activity in liver mitochondria Cavia porcellus anthranilamide + NAD+ + H2O
-
?
anthranillic hydroxamate + NADH + H+ activity in liver mitochondria Mus musculus anthranilamide + NAD+ + H2O
-
?
anthranillic hydroxamate + NADH + H+ activity in liver mitochondria Rattus norvegicus anthranilamide + NAD+ + H2O
-
?
anthranillic hydroxamate + NADH + H+ activity in liver mitochondria Bos taurus anthranilamide + NAD+ + H2O
-
?
anthranillic hydroxamate + NADH + H+ activity in liver mitochondria Oryctolagus cuniculus anthranilamide + NAD+ + H2O
-
?
anthranillic hydroxamate + NADH + H+ activity in liver mitochondria Ovis aries anthranilamide + NAD+ + H2O
-
?
anthranillic hydroxamate + NADH + H+ activity in liver mitochondria Pigeon anthranilamide + NAD+ + H2O
-
?
anthranillic hydroxamate + NADH + H+ activity in liver mitochondria Canis lupus familiaris anthranilamide + NAD+ + H2O
-
?
anthranillic hydroxamate + NADH + H+ activity in liver mitochondria Didelphidae anthranilamide + NAD+ + H2O
-
?
anthranillic hydroxamate + NADH + H+ activity in liver mitochondria Cricetinae anthranilamide + NAD+ + H2O
-
?
hydroxylamine + NADH
-
Gallus gallus NH3 + NAD+ + H2O
-
?
hydroxylamine + NADH
-
Cavia porcellus NH3 + NAD+ + H2O
-
?
hydroxylamine + NADH
-
Mus musculus NH3 + NAD+ + H2O
-
?
hydroxylamine + NADH
-
Sus scrofa NH3 + NAD+ + H2O
-
?
hydroxylamine + NADH
-
Bos taurus NH3 + NAD+ + H2O
-
?
hydroxylamine + NADH
-
Oryctolagus cuniculus NH3 + NAD+ + H2O
-
?
hydroxylamine + NADH
-
Ovis aries NH3 + NAD+ + H2O
-
?
hydroxylamine + NADH
-
Pigeon NH3 + NAD+ + H2O
-
?
hydroxylamine + NADH
-
Canis lupus familiaris NH3 + NAD+ + H2O
-
?
hydroxylamine + NADH
-
Didelphidae NH3 + NAD+ + H2O
-
?
hydroxylamine + NADH
-
Cricetinae NH3 + NAD+ + H2O
-
?
hydroxylamine + NADH very low activity with phenylhydroxylamine Rattus norvegicus NH3 + NAD+ + H2O
-
?
hydroxylamine + NADH no reduction of N,N-diethyl or O-methyl compounds Rattus norvegicus NH3 + NAD+ + H2O
-
?
N-methylhydroxylamine + NADH
-
Rattus norvegicus methylamine + NAD+ + H2O
-
?
N-methylhydroxylamine + NADH
-
Sus scrofa methylamine + NAD+ + H2O
-
?
phenylhydroxylamine + NADH
-
Rattus norvegicus phenylamine + NAD+ + H2O
-
?
phenylhydroxylamine + NADH
-
Sus scrofa phenylamine + NAD+ + H2O
-
?

Cofactor

Cofactor Comment Organism Structure
NADH
-
Gallus gallus
NADH
-
Cavia porcellus
NADH
-
Mus musculus
NADH
-
Rattus norvegicus
NADH
-
Sus scrofa
NADH
-
Bos taurus
NADH
-
Oryctolagus cuniculus
NADH
-
Ovis aries
NADH
-
Pigeon
NADH
-
Canis lupus familiaris
NADH
-
Didelphidae
NADH
-
Cricetinae