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Literature summary for 1.7.1.13 extracted from

  • Swairjo, M.A.; Reddy, R.R.; Lee, B.; Van Lanen, S.G.; Brown, S.; de Crecy-Lagard, V.; Iwata-Reuyl, D.; Schimmel, P.
    Crystallization and preliminary x-ray characterization of the nitrile reductase QueF: a queuosine-biosynthesis enzyme (2005), Acta Crystallogr. Sect. F, F61, 945-948.
    View publication on PubMedView publication on EuropePMC

Crystallization (Commentary)

Crystallization (Comment) Organism
sitting-drop vapor-diffusion method, space group: P3(1)21. Unit-cell parameters: a = b = 93.52 A, c = 193.76 A Bacillus subtilis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
7-cyano-7-deazaguanine + 2 NADPH + 2 H+ Bacillus subtilis late step in biosynthesis of the modified tRNA nucleoside queuosine queuine + 2 NADP+
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?

Organism

Organism UniProt Comment Textmining
Bacillus subtilis O31678
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-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7-cyano-7-deazaguanine + 2 NADPH + 2 H+ late step in biosynthesis of the modified tRNA nucleoside queuosine Bacillus subtilis queuine + 2 NADP+
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?

Subunits

Subunits Comment Organism
decamer
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Bacillus subtilis

Synonyms

Synonyms Comment Organism
7-aminomethyl-7-carbaguanine:NADP+ oxidoreductase
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Bacillus subtilis
7-cyano-7-deazaguanine reductase
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Bacillus subtilis
preQ0 reductase
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Bacillus subtilis
preQ0oxidoreductase
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Bacillus subtilis
QueF
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Bacillus subtilis
YkvM
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Bacillus subtilis

Cofactor

Cofactor Comment Organism Structure
NADPH
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Bacillus subtilis